Ocular manifestations and treatment safety in hepatitis C patients undergoing direct-acting antiviral therapy: a prospective cohort study by Guilherme Thomé de Carvalho, Carlos Eduardo Brandão Mello, Kelma Macedo Pohlmann Simões, Mário Martins dos Santos Motta, Max Kopti Fakoury, Bruno Vasconcelos Coimbra, Laura Gomes Nunes Melo, Flávio Mac Cord Medina

“…All patients achieved sustained virological response, and a notable improvement in fibrosis degree post-treatment was observed. No ocular complications attributable to direct-acting antiviral therapy were reported during the study. …”
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Heme alters biofilm formation in Mycobacterium abscessus by Hadia Aftab, Jessica Samudio, Grace Wang, Lily Le, Rajesh K. Soni, Rebecca K. Donegan

“…ABSTRACT Mycobacterium abscessus (Mabs) is commonly found in the cystic fibrosis (CF) lung. During infection, Mabs can form biofilms in the lung which reduce both the ability of the immune response to clear infection and the effectiveness of antibiotic therapy. …”
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Higher risk of carotid plaque among lean individuals with non-alcoholic fatty liver disease: A retrospective study. by Jiangfeng Xue, Lun Zhao, Liang Shao, Huiwang Zhang, Yewei Feng, Ping Shuai

“…Age, gender, systolic blood pressure, low-density lipoprotein cholesterol, fasting blood glucose, and Fibrosis-4 index (FIB-4) were identified as independent risk factors with cutoff values lower than the normal upper limits. …”
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Treatment of Nonalcoholic Steatohepatitis in Adults: Present and Future by S. Gitto, G. Vitale, E. Villa, P. Andreone

“…Nevertheless, vitamin E has no proven effect on fibrosis and on long-term morbidity and mortality and pioglitazone has a negative impact on weight. …”
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Serum Activins and Follistatin during the Treatment of Chronic Hepatitis C Genotypes 1 and 4 and Their Correlations with Viral Load and Liver Enzymes: A Preliminary Report by Bassem Refaat, Adel Galal El-Shemi, Ahmed Mohamed Ashshi, Adnan AlZanbagi

“…Serum candidate proteins were measured using ELISA and liver fibrosis was assessed by AST platelet ratio index (APRI). …”
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Ultrasonographic evaluation of the thorax in dogs with tick paralysis by Erdem Gülersoy, Canberk Balıkçı, İsmail Günal, Adem Şahan, Esma Kısmet

“…The presence of pulmonary nodule and fibrosis might be due to bronchopneumonia and aspiration pneumonia due to regurgitation. …”
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Quercetin Inhibits Pyroptosis in Diabetic Cardiomyopathy through the Nrf2 Pathway by Zhang Wei, Zhou Jing, Kang Pinfang, Shi Chao, Qian Shaohuan

“…We evaluated the protective effects of quercetin against diabetic cardiomyopathy by analyzing the expression of pyroptosis pathway proteins, myocardial cell apoptosis rate, degree of myocardial fibrosis, and serum inflammatory indices in the hearts of model rats with diabetes. …”
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Iris from Iridectomy Used as Spacer underneath the Scleral Flap: The Iridenflip Trabeculectomy Technique by Veva De Groot, Liselotte Aerts, Stefan Kiekens, Tanja Coeckelbergh, Marie-José Tassignon

“…We describe a modified trabeculectomy technique in which the iris is used to prevent fibrosis of the scleral flap. Material and Methods. …”
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IgG4-Related Sclerosing Cholangitis Involving the Intrahepatic Bile Ducts Diagnosed with Liver Biopsy by Malene Theilmann Thinesen, Ove B. Schaffalitzky de Muckadell, Sönke Detlefsen

“…IgG4-related disease is characterized by lymphoplasmacytic inflammation and fibrosis, often leading to mass-forming lesions in different organs. …”
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MFG-E8 Knockout Aggravated Nonalcoholic Steatohepatitis by Promoting the Activation of TLR4/NF-κB Signaling in Mice by Jun Hu, Hui Du, Yinglin Yuan, Peipei Guo, Junxia Yang, Xinru Yin, Jin Liu, Shengwang Wu, Jingyuan Wan, Xia Gong

“…Nonalcoholic steatohepatitis (NASH) is the common liver disease characterized by hepatic steatosis, inflammation, and fibrosis; there are no approved drugs to treat this disease because of incomplete understanding of pathophysiological mechanisms of NASH. …”
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Syndecan-4 is More Sensitive in Detecting Hypertensive Left Ventricular Diastolic Dysfunction in 2K2C Rats by Wenyue Dai, Yanqiu Liu, Fengjuan Yao, Wei Li, Jia Liu, Cuiling Li, Donghong Liu

“…In the earlier 4 weeks, only SDC-4 and cardiac fibrosis were significantly increased in 2K2C hypertensive rats in comparison with normotensive rats. …”
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“Etiology and CT pattern in patients with interstial lung disease”: shift in the trends? by Abhishek Samdesi, Alamelu Haran, Navya Chinnaswamy Narayanaswamy

“…Second most common etiology was Idiopathic Pulmonary Fibrosis (IPF) (n=15, 14.42%). The UIP pattern was observed in 59.32% patients with CTD-ILD (n = 35) and in 100% patients with the IPF. …”
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Nonalcoholic Fatty Liver Disease in Canadian First Nations and Non-First Nations Patients by Julia Uhanova, Gerald Minuk, Federico Lopez Ficher, Natasha Chandok

“…Noninvasive tests of fibrosis (APRI and NAFLD fibrosis scores) were also similar in the two cohorts. …”
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Reduced tracheal stenosing effect of nintedanib in a patient with scarred posttraumatic tracheal stenosis and airflow limitation - a case report by Stefanie Klampfleitner, Andreas Fertl, Ositha Prinz, Martin Doerfler-Schalm, Dieter Munker, Markus O. Henke

“…Introduction: Nintedanib is a tyrosine kinase inhibitor and has been approved for the treatment of idiopathic pulmonary fibrosis (IPF) since 2020. In Clinical trials, the antifibrotic effect of nintedanib was shown. …”
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Benidipine Protects Kidney through Inhibiting ROCK1 Activity and Reducing the Epithelium-Mesenchymal Transdifferentiation in Type 1 Diabetic Rats by Ganlin Wu, Meirong Xu, Kui Xu, Yilan Hu

“…In conclusion, benidipine reduces the epithelium-mesenchymal transdifferentiation and renal interstitial fibrosis in diabetic kidney by inhibiting ROCK1 activity.…”
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Prevalence and features of allergic bronchopulmonary aspergillosis, United States, 2016-2022. by Kaitlin Benedict, Jeremy A W Gold, Mitsuru Toda, Joy Hsu

“…To estimate national ABPA prevalence among patients with asthma or cystic fibrosis, characterize ABPA testing practices, and describe ABPA clinical features, treatment, and 6-month outcomes. …”
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Efficacy and safety of the Russian protease inhibitor narlaprevir at treatment-naive and earlier treated noncirrhotic patients with the 1st genotype chronic hepatitis C (PIONEER st... by M. V. Mayevskaya, V. T. Ivashkin, O. O. Znoyko, Ye. A. Klimova, D. T. Abdurakhmanov, I. G. Bakulin, P. O. Bogomolov, E. Z. Burnevich, M. Yu. Galushko, N. I. Geyvandova, K. V. Zhdanov, Ye. V. Esaulenko, S. N. Kizhlo, D. Yu. Konstantinov, N. I. Mironova, V. G. Morozov, Ye. A. Strebkova, I. G. Nikitin, M. F. Osipenko, V. D. Pasechnikov, O. I. Sagalova, I. M. Khayertynova, V. P. Chulanov, A. A. Yakovlev, I. A. Vasyutin, Ye. P. Tarkhova, E. N. Krasavina, M. Yu. Samsonov

“…In treatment-naïve patients from the main group SVR24 was achieved in 90.8% at initial METAVIR F0-F2 liver fibrosis stage and in 75% at F3 liver fibrosis stage. …”
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Serum Lactate Dehydrogenase Is a Novel Predictor for the Severity in the Patients With MAFLD: A Cross-Sectional Study in Hefei, China by Yu L, Bao S, Zhu F, Xu Y, Zu F, Liu Y, Jiang R, Chen S, Chen W

“…Logistic regression showed that LDH was significantly and positively correlated with MAFLD, B.MASH, MASH, at-risk MASH, fibrosis grade ≥ 1, fibrosis grade ≥ 2 and fibrosis grade ≥ 3.Conclusion: Increased LDH levels were significantly and independently associated with the presence and severity of metabolic syndrome and MAFLD, indicating that LDH could be used as a novel biomarker and clinical predictor of severity of metabolic syndrome and MAFLD.Keywords: lactate dehydrogenase, obesity, metabolic syndrome, inflammation, metabolic associated fatty liver disease, (MAFLD)…”
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The Antifibrosis Effects of Peroxisome Proliferator-Activated Receptor δ on Rat Corneal Wound Healing after Excimer Laser Keratectomy by Yun Gu, Xuan Li, Tiangeng He, Zhixin Jiang, Peng Hao, Xin Tang

“…Corneal stromal fibrosis characterized by myofibroblasts and abnormal extracellular matrix (ECM) is usually the result of inappropriate wound healing. …”
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Immunopathology of Airway Surface Liquid Dehydration Disease by Brandon W. Lewis, Sonika Patial, Yogesh Saini

“…Defective MCC is often associated with airway mucoobstruction, increased occurrence of respiratory infections, and progressive decrease in lung function in mucoobstructive lung diseases including cystic fibrosis (CF). In this disease, a mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene results in dehydration of the airway surface liquid (ASL) layer. …”
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