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661
A Cytokine That Is Involved in Immune Responses in Chronic Hepatitis B Virus Patients
Published 2024-01-01“…Conclusion: The investigation comes to the conclusion that IL-17 levels increase as liver disease severity increases, suggesting that it is involved in the development of fibrosis and the progression of the disease. Gaining insight into the function of IL-17 may help develop more effective therapies for CHB and LC patients. …”
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663
Major Histocompatibility Class II Pathway Is Not Required for the Development of Nonalcoholic Fatty Liver Disease in Mice
Published 2013-01-01“…The CCl4 treatment significantly induced genes related to the fibrosis formation in wild-type mice, whereas this was lower in MHCIIΔ/Δ mice. …”
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664
Choice of Allograft in Patients Requiring Intestinal Transplantation: A Critical Review
Published 2017-01-01“…Thus, patients with cirrhosis or advanced fibrosis should receive a combined allograft, while patients with lower grades of liver fibrosis can usually safely undergo ITx. …”
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665
Assessment and follow-up of interstitial lung disease
Published 2021-01-01“…Screening guidelines based on expert opinion are available for idiopathic pulmonary fibrosis (IPF) and non-IPF ILDs (sarcoidosis, hypersensitivity pneumonitis, and systemic sclerosis). …”
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666
Type 2 Diabetes Mellitus, a Sequel of Untreated Childhood Onset Growth Hormone Deficiency Developing in a 17-Year-Old Patient
Published 2018-01-01“…We present a 17-year-old nonobese female with untreated childhood onset growth hormone deficiency (CO-GHD) who developed type 2 diabetes mellitus (T2DM) and steatohepatitis with bridging fibrosis. Based on height z-score of – 3.1 and a history of radiation therapy as treatment for a medulloblastoma at 7 years of age, GHD was quite likely. …”
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667
Corrosive induced esophageal and gastric injury: Histopathological evaluation of surgically resected specimens over a decade in a tertiary care center
Published 2024-04-01“…Conclusion: Caustic ingestion leads to mucosal ulceration, transmural inflammation, and transmural fibrosis which might be the reason for refractory stricture in such patients.…”
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668
A combination of ursodeoxycholic acid and Allium sativum prevents liver cirrhosis in cholestatic rats
Published 2025-03-01“…Cholestasis causes liver cirrhosis due to chronic total obstruction, in which accumulated bile acids induce liver inflammation and fibrosis. Inflammatory conditions are associated with hypoalbuminemia, and changes in albumin levels indicate the patient's clinical condition. …”
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669
Combined Effects of PPARγ Agonists and Epidermal Growth Factor Receptor Inhibitors in Human Proximal Tubule Cells
Published 2013-01-01“…Our data suggests that combination of an EGFR inhibitor and a PPARγ agonist mitigates high-glucose-induced fibrosis and inflammation and reverses the upregulation of transporters and channels involved in sodium and water retention in human proximal tubule cells. …”
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670
Post Covid-19 Syndromes, The Time line of Covid
Published 2023-01-01“…Persistent post-Covid syndrome (PPCS), Myocarditis. Lung Fibrosis. …”
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671
Validation of the Chronic Liver Disease Questionnaire for MASH (CLDQ-MASH)
Published 2025-03-01“…In a subsample of subjects with 1-year follow-up, the instrument was responsive to changes in Enhanced Liver Fibrosis® scores and liver stiffness measurements (p <0.05 for four to six domains). …”
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672
Spironolactone Protects against Diabetic Cardiomyopathy in Streptozotocin-Induced Diabetic Rats
Published 2018-01-01“…Compared to the STZ + NS group, cardiac oxidative stress, fibrosis, inflammation, and mitochondrial dysfunction were improved by SPR treatment. …”
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673
miRNAs and Hematological Markers in Non-Alcoholic Fatty Liver Disease—A New Diagnostic Path?
Published 2025-01-01“…Therefore, we decided to explore relationships between selected types of microRNAs (miRNAs), serological markers of liver fibrosis and hematological parameters in the course of non-alcoholic fatty liver disease (NAFLD). …”
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674
miRNA-221: A Potential Biomarker of Progressive Liver Injury in Chronic Liver Disease (CLD) due to Hepatitis B Virus (HBV) and Nonalcoholic Fatty Liver Disease (NAFLD)
Published 2024-01-01“…Conclusion: miRNA-221 may be used as a potential plasma biomarker for early prediction of fibrosis progression in CLD patients.…”
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675
Characterization of liver, adipose, and fecal microbiome in obese patients with MASLD: links with disease severity and metabolic dysfunction parameters
Published 2025-01-01“…Brevibacterium is enriched in adipose tissues of patients with liver fibrosis. Conclusion Together, these results provide further insight into the microbial factors that may be driving disease severity. …”
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676
Can Spinal Bupivacaine Analgesia Treatment Make a Difference on Urinary Bladder Healing According to the Intramuscular Pethidine Analgesia Treatment in Rats?
Published 2007-01-01“…Specimens, particularly the incised region of the bladder, were evaluated for inflammation and fibrosis. Grading scales were used for this purpose. …”
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677
Analytical and Clinical Evaluation of a Chemiluminescent Immunoassay to Detect Serum Chitinase-3-like Protein 1 in HBV-Related Liver Diseases
Published 2024-01-01“…Correlation analysis revealed a significant association between CHI3L1 and alpha-fetoprotein (AFP) levels, the fibrosis-4 (FIB-4) index, and the aspartate aminotransferase-to-platelet ratio index (APRI). …”
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678
Upregulated FoxO1 promotes arrhythmogenesis in mice with heart failure and preserved ejection fraction
Published 2025-01-01“…Abstract Myocardial fibrosis leads to cardiac dysfunction and arrhythmias in heart failure with preserved ejection fraction (HFpEF), but the underlying mechanisms remain poorly understood. …”
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679
Metalloproteinases and their Inhibitors under the Course of Immunostimulation by CPG-ODN and Specific Antigen Inhalation in Equine Asthma
Published 2019-01-01“…CpG-ODN inhalation may be an effective therapy in the prevention of pulmonary fibrosis formation in equine asthma.…”
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680
Application of Nanomaterial-Mediated Ferroptosis Regulation in Kidney Disease
Published 2025-02-01“…Jiamin Zhu,1,* Zhen Zhang,1,2,* Yanhui Chu,1,* Zhongyin Xie,1 Dongmei Zeng,1 Lijiao Jin,1 Luxin Li1 1Heilongjiang Key Laboratory of Anti-Fibrosis Biotherapy, Mudanjiang Medical University, Mudanjiang, People’s Republic of China; 2School of First Clinical Medical College, Mudanjiang Medical University, Mudanjiang, People’s Republic of China*These authors contributed equally to this workCorrespondence: Luxin Li, Heilongjiang Key Laboratory of Anti-Fibrosis Biotherapy, Mudanjiang Medical University, Mudanjiang, 157000, People’s Republic of China, Tel +86 13763617174, Email liluxin@mdjmu.edu.cnAbstract: Kidney diseases are a significant global cause of death and disability, resulting from the destruction of kidney structure and function due to an imbalance between the death of renal parenchymal cells and the proliferation or recruitment of maladaptive cells, caused by various pathogenic factors. …”
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