Impact of Myo-Inositol-Chiro Inositol Combination on the improvement of Polycystic Ovary Syndrome Condition by Zuhair Assi Hussein, Maysaa Jalal Majeed, Lubna Amer Al-Anbari

“…In the study, 50 obese women without PCOS, and 50 obese women with PCOS were enrolled, and they were then treated with 2000 mg of myo-inositol (MI) and 50 mg of D-chiro inositol (DCI) in a 40:1 ratio for 3 months while having their vital signs and laboratory tests checked both before and after the treatment. We examined fasting glucose, insulin, ILP5, PDE9 inhibitor, free testosterone, dehydroepiandrosterone, the homeostatic model assessment index, and pretreatment and posttreatment. …”
Get full text

Predictors for Gingival Index in Middle-Aged Asian Indians with Type 2 Diabetes from South India: A Cross-Sectional Observational Study by S. Jai Karthik, Shajith Anoop, R. Suresh Kumar, M. V. Usha Rani

“…Dental examinations for pocket depth (PD) and clinical attachment level (CAL) were performed and gingival index was calculated. Fasting venous blood samples were analysed for measures of glycaemia and cholesterol. …”
Get full text

Superior bioavailability of EPA and DHA from a L-lysine salt formulation: a randomized, three-way crossover study by Christiane Schön, Antje Micka, Vishnupriya Gourineni, Roberta Bosi

“…ΔCmax and Tmax also favored Lys-FFA over EE. Discussion: Under fasting conditions, the absorption of EPA and DHA from EE is limited due to the need for enzymatic cleavage before absorption. …”
Get full text

The Determinants of Adolescent Glycolipid Metabolism Disorder: A Cohort Study by Xiao-Hua Liang, Lun Xiao, Jing-Yu Chen, Ping Qu, Xian Tang, Yuwei Wang

“…Subjects with an urban residence, no pubertal development, dyslipidemia in 2014, higher family income, and higher parental education had significantly elevated fasting insulin (FI) or homeostasis model assessment of insulin resistance (HOMA-IR) levels; subjects with female sex, no pubertal development, dyslipidemia in 2014, obesity, gestational hypertension, maternal weight gain above Institute of Medicine guidelines, and single parents had increased triglyceride or triglyceride/high-density lipoprotein (HDL). …”
Get full text

Impact of Endurance Exercise Training on Biomarkers of Aortic Endothelial Damage in Diabetic Rats by Mahtab Fouladi, Maryam Mahmoudabady, Zahra Gholamnezhad, Sadegh Shabab, Saeed Niazmand, Hossein Salmani

“…After 6 weeks, biochemical parameters in serum and oxidative stress markers and mRNA expression of endothelial nitric oxide synthase (eNOS), lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1), and intercellular adhesion molecule-1 (ICAM-1) in aorta tissue were assessed. Serum levels of fasting blood sugar (FBS), triglyceride (TG), total cholesterol (TC), low-density lipoprotein (LDL), TG/HDL, TC/HDL, and LDL/HDL ratios were significantly reduced in all treatment groups compared to the diabetes group. …”
Get full text

Multiomics Integrated Analysis Identifies SLC24A2 as a Potential Link between Type 2 Diabetes and Cancer by Qin Bian, Haijun Li, Xiaoyi Wang, Tingting Liang, Kai Zhang

“…SLC24A2 was first identified as a key gene strongly associated with fasting plasma glucose (FPG). Then, overlapped differentially expressed genes (DEGs) between T2D verse control and SLC24A2-high verse SLC24A2-low were extracted and imported into weighted correlation network analysis. …”
Get full text

Prevalence and factors associated with non-alcoholic fatty liver disease among women with polycystic ovary syndrome by Maria Elisa Franciscatto, Juliana Bosso Taniguchi, Raquel Wohlenberg, Isadora Luísa Riedi, Karen Oppermann

“…The NAFLD group had higher weight (p=0.003), BMI (p=0.001), waist circumference (p≤0.001), fasting glucose (p=0.021), HbA1C% (p=0.028), triglycerides (p=0.023), AST (p=0.004), ALT (p=0.001), higher prevalence of MS (p=0.004), and lower levels of HDL cholesterol (p=0.043). …”
Get full text

Risk factors and preventive measures for abnormal blood pressure during hemodialysis filtration for patients with sepsis by Zhang Chunfang, Lin Tingting, Xia Yu, Zhang Daowei

“…Multivariate logistic regression analysis revealed that age, blood calcium, fasting plasma glucose, intact parathyroid hormone, ultrafiltration volume, and ultrafiltration rate were independent risk factors, whereas albumin was a protective factor for ABP during HDF (p < 0.05). …”
Get full text

Results of a Randomized, Open-Label, Clinical Trial Investigating the Effects of Supplementation with Heracleum persicum Extract as an Adjunctive Therapy for Dyslipidemia by Yunes Panahi, Bahram Pishgoo, Fatemeh Beiraghdar, Zahra Mohammadi Araghi, Amirhossein Sahebkar, Ehsan Abolhasani

“…In comparison with baseline values, no significant change was observed in weight and BMI, as well as serum levels of creatinine, blood urea nitrogen, and fasting blood sugar in either of the groups (p > 0.05). …”
Get full text

Determination of Irisin, Body Mass Index, and Other Biochemical Parameters in a Sample of Iraqi Type II Diabetic Patients by Takwa Al Koloob Ali Chachan, Huda Farhan, Shatha Hamed

“…Irisin seems to have a significant negative connection [P-value<0.001] with body mass index, fasting blood sugar, glycated hemoglobin, insulin, and homeostasis model assessment of insulin resistance. …”
Get full text

Comparison of Asymptomatic Brain Lesions Between Thalassemia Major and Sickle Cell Anemia Patients by Derya Yavuz Demiray, Özge Eriş Davut, Gönül Oktay

“…Variables including age, years of education, presence and type of MRI-detected ischemia, smoking status, hemoglobin, hematocrit, platelet count, ferritin levels, vitamin B12 levels, fasting blood sugar, splenectomy status, chelation therapy, and hydroxyurea treatment were compared between the two groups. …”
Get full text

Visceral Adipose Tissue Inflammation and Vascular Complications in a Rat Model with Severe Dyslipidemia: Sex Differences and PAI-1 Tissue Involvement by Irena Markova, Martina Hüttl, Natalie Gayova, Denisa Miklankova, Kristyna Cerna, Martina Kavanova, Petra Skaroupkova, Sona Cacanyiova, Hana Malinska

“…Using male and female hereditary hypertriglyceridemic (HHTg) rats—a nonobese prediabetic model featuring dyslipidemia, hepatic steatosis, and insulin resistance—we found that HHTg females exhibited more pronounced hypertriglyceridemia than males, while HHTg males had higher non-fasting glucose levels. Additionally, HHTg females had higher platelet counts, larger platelet volumes, and lower antithrombin inhibitory activity. …”
Get full text

Engaging Primary Care Professionals and People at Risk of Type 2 Diabetes in the Design of PREDIABETEXT, a Multifaceted Digital Intervention Aimed at Preventing Type 2 Diabetes: A... by Maria Jesús Serrano-Ripoll, Rocío Zamanillo-Campos, Sofía Mira Martínez, Maria Antònia Fiol-deRoque, Narges Malih, Escarlata Angullo-Martínez, Ignacio Ricci-Cabello

“…Methods: in this qualitative study, we purposefully recruited 15 healthcare professionals (doctors and nurses) working in primary healthcare centers in Mallorca (Spain), and 15 of their patients at risk of T2DM (HbA1c 6–6.4%, and/or fasting plasma glucose 110–125 mg/dL). We collected the data through semi-structured phone interviews, using an interview guide aimed at gathering participants’ views about the two PREDIABETEXT proposed co-interventions (educational intervention targeted at professionals and delivered as an online training course, and behavioral intervention targeted at individuals at risk of T2DM and delivered using SMS short text messages). …”
Get full text

A Cross-Sectional Study Demonstrating Increased Serum Amyloid A Related Inflammation in High-Density Lipoproteins from Subjects with Type 1 Diabetes Mellitus and How This Associati... by Jane McEneny, Jane-Ann Daniels, Anne McGowan, Anjuli Gunness, Kevin Moore, Michael Stevenson, Ian S. Young, James Gibney

“…Normally high-density lipoproteins (HDL) protect against atherosclerosis; however, in the presence of serum amyloid-A- (SAA-) related inflammation this property may be reduced. Fasting blood was obtained from fifty subjects with T1DM, together with fifty age, gender and BMI matched control subjects. …”
Get full text

The prevention opportunities of retinopathy in diabetic patients – position paper endorsed by the Polish Lipid Association by Maciej Banach, Stanisław Surma, Grzegorz Dzida, Jacek Jóźwiak, Bogusław Okopień, Jacek Rysz, Konrad Szosland, Andrzej Grzybowski

“…Thus, given the obesity (the prevalence of 30% in Poland) and diabetes (10% which is predicted to be doubled in next 25 years) epidemic, we should look for the effective methods not only to optimize fasting blood glucose and haemoglobin A1C, but also atherogenic dyslipidaemia and their complications, including retinopathy. …”
Get full text

Blood metabolomic profile in patients with type 2 diabetes mellitus with diabetic peripheral neuropathic pain by Hung‐Chou Kuo, Chia‐Ni Lin, Sung‐Sheng Tsai, Chiung‐Mei Chen, Rong‐Kuo Lyu, Chun‐Che Chu, Long‐Sun Ro, Ming‐Feng Liao, Hong‐Shiu Chang, Yi‐Ching Weng, Jawl‐Shan Hwang

“…DPNP patients showed elevated fasting blood glucose, glutamate, PC aa C36:1, lysoPC a C18:1, and lysoPC a C18:2, while low‐density lipoprotein cholesterol, phenylalanine, and tryptophan were reduced. …”
Get full text

Burden of type 2 diabetes and its relationship with human development index in Asian countries: Global Burden of Disease Study in 2019 by Seyed Ahmadreza Alinaghian, Shokoufeh Hamidzadeh, Afsaneh Badrizadeh, Zaher Khazaei, Amirhossein Souri, Victoria Momenabadi, Elham Goodarzi

“…According to the results, air pollution, high fasting plasma glucose, and dietary risks are the main risk factors associated with the burden of type 2 diabetes in women and men, respectively. …”
Get full text

Resveratrol enhances post-injury muscle regeneration by regulating antioxidant and mitochondrial biogenesis by Xiaoli Qin, Wenjing Niu, Kai Zhao, Yawen Luo, Wenfang Wang, Yang He, Fuyu Yang, Binghai Cao, Min Du, Huawei Su

“…RES treatment significantly increased the ratio of tibialis anterior muscle mass to body weight, alongside reduced fasting glucose levels. Following cardiotoxin-induced injury, RES treatment improved muscle regeneration, characterized by greater formation of new fibers and better structural repair compared to the control. …”
Get full text

The Risk Factors for Diabetic Retinopathy in a Chinese Population: A Cross-Sectional Study by Qingmin Sun, Yali Jing, Bingjie Zhang, Tianwei Gu, Ran Meng, Jie Sun, Dalong Zhu, Yaping Wang

“…The patients in the DR group not only had significantly higher hemoglobin A1c (HbA1c), fasting plasma glucose (FPG), urinary microalbumin-creatinine ratio (ACR), and systolic blood pressure but also had higher follicle-stimulating hormone (FSH), luteinizing hormone (LH), and sex hormone-binding globulin (SHBG) levels compared to those in the non-DR group. …”
Get full text

Distribution of Abdominal Obesity and Fitness Level in Overweight and Obese Korean Adults by Sue Kim, Ji-Young Kim, Duk-Chul Lee, Hye-Sun Lee, Ji-Won Lee, Justin Y. Jeon

“…Through stepwise multiple regression analyses after adjustment for age, sex, BMI, lifestyle factors, mean blood pressure, fasting glucose, HOMA-IR, lipid profiles, and hsCRP, recovery heart rate was identified as an independent variable associated with VAT (β=0.204, P<0.001) and VAT/SAT ratio (β=0.163, P=0.008) but not with SAT (β=0.097, P=0.111). …”
Get full text