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Integrative Bioinformatics Analysis to Identify Key Ferroptosis-Related Genes and Immune Infiltration in Aortic Aneurysm and Dissection: Implication of PTGS2
Published 2025-01-01“…All these FRGs were significantly increased in patients with aortic aneurysm. …”
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Bioinformatic analysis of ferroptosis related biomarkers and potential therapeutic targets in vitiligo
Published 2025-01-01“…We identified 31 differentially expressed FRGs (DE-FRGs), with 21 genes upregulated and 10 downregulated. …”
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Correlation between Ferroptosis-Related Gene Signature and Immune Landscape, Prognosis in Breast Cancer
Published 2022-01-01“…The expressions of the six FRGs were verified with real-time quantitative polymerase chain reaction and immunohistochemistry in the Human Protein Atlas. …”
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To Develop Biomarkers for Diabetic Nephropathy Based on Genes Related to Fibrosis and Propionate Metabolism and Their Functional Validation
Published 2024-01-01“…Second, the intersection of DN-DEGs, PM-DEGs, and FRGs was taken to yield intersected genes. Random forest (RF) and recursive feature elimination (RFE) analyses of the intersected genes were performed to sift out biomarkers. …”
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A Novel Ferroptosis-Related Gene Signature for Prognosis Prediction in Ewing Sarcoma
Published 2022-01-01“…Here, 148 differentially expressed FRGs (DEFRGs) were identified between normal and ES tissue. …”
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Targeting ferroptosis for improved radiotherapy outcomes in HPV‐negative head and neck squamous cell carcinoma
Published 2025-02-01“…This ferroptosis‐related gene signature (FRGS) was a significant predictor of overall survival and recurrence‐free survival in HPV‐negative HNSCC patients who received RT. …”
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Dicoumarol sensitizes hepatocellular carcinoma cells to ferroptosis induced by imidazole ketone erastin
Published 2025-02-01“…Differentially expressed genes were identified and intersected with the ferroptosis-related genes (FRGs) listed in the FerrDb database, yielding the identification of 13 distinct FRGs.ResultsA ferroptosis signature index model (Risk Score) was developed to predict HCC prognosis. …”
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Exploring the Kidney-Brain Crosstalk: Biomarkers for Early Detection of Kidney Injury-Related Alzheimer’s Disease
Published 2025-01-01“…Subsequently, bioinformatics and machine learning techniques were used to identify biomarkers for KI-associated ferroptosis-related genes (FRGs) in AD, which were validated in following experiments. …”
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