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Topical Osmoprotectant for the Management of Postrefractive Surgery-Induced Dry Eye Symptoms: A Randomised Controlled Double-Blind Trial
Published 2018-01-01“…Background. Dry eye disease (DED) is one of the most common complications following refractive surgery. …”
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102
Design of Highly Adhesive Urchin‐Like Gold Nanostructures for Effective Topical Drug Administration and Symptomatic Relief of Corneal Dryness
Published 2025-02-01“…Topical instillation of cyclosporin A (an anti‐inflammatory drug) is clinically recommended as the first‐line treatment for dry eye disease. Nevertheless, it suffers from poor ocular drug retention and cannot comprehensively address corneal dryness‐related symptoms such as oxidative stress, angiogenesis, and neurodegeneration. …”
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103
Corneal Epithelial Thickness Mapping: A Major Review
Published 2024-01-01“…Alterations in ETM in systemic and ocular conditions such as eyelid abnormalities and dry eye disease and the effects of contact lenses, topical medications, and cataract surgery on the ETM profile are discussed.…”
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104
The Application of Terahertz Technology in Corneas and Corneal Diseases: A Systematic Review
Published 2025-01-01“…This systematic review provides an overview of the characteristics of THz waves, the safety profile of THz technology in the field of ophthalmology, and its clinical applications, including the objective evaluation of the corneal hydration, tear film, dry eye disease, corneal endothelium, corneal elasticity, and scarring. …”
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105
Relationship of Retinal Vessel Caliber with Age-Related Macular Degeneration
Published 2022-01-01“…A retrospective secondary analysis of 1172 fundus photographs and clinical data from the prospective Age-Related Eye Disease Study (AREDS). Central retinal artery equivalent (CRAE), central retinal vein equivalent (CRVE), and arteriole-to-venule ratio (AVR) were measured using the Parr–Hubbard–Knudtson formula. …”
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106
An Ensemble Based Machine Learning Classification for Automated Glaucoma Detection
Published 2024-12-01“…Glaucoma is an irredeemable eye disease that causes sight degeneration and is the fourth leading cause of vision impairment as per the World Report on Vision 2019. …”
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107
Study on the mechanism of plant metabolites to intervene oxidative stress in diabetic retinopathy
Published 2025-02-01“…Diabetic retinopathy is the main microvascular complication of diabetes and the first blinding eye disease in the working-age population. Oxidative stress is an important pathogenesis of diabetic retinopathy. …”
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108
Reduced Expression of VAMP8 in Lacrimal Gland Affected by Chronic Graft-versus-Host Disease
Published 2017-01-01“…Collectively, the reduction of VAMP8 expression in the cGVHD-affected LG can be involved in the pathogenic processes of cGVHD-induced dry eye disease.…”
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109
Analysis of macular retinal thickness in polyarteritis nodosa using spectral domain optical coherence tomography
Published 2025-01-01“…Methods A total of 24 PAN patients who had been for 3 years or more and underwent SD-OCT were recruited from the UK Biobank, with exclusions for diabetes, eye disease, or abnormal CFP findings. Only the right eyes were included, with each PAN patient paired one-to-one with a control matched for age, sex, and ethnicity. …”
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110
Annual versus biannual azithromycin mass drug administration for the elimination of infectious trachoma in Africa: protocol for a systematic review and meta-analysis using data fro...
Published 2025-02-01“…Introduction Trachoma is an infectious eye disease caused by Chlamydia trachomatis and the leading infectious cause of blindness worldwide. …”
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111
Long-term Results of Topical Insulin Treatment for Persistent Corneal Epithelial Defects
Published 2024-12-01“…Results: Neurotrophic keratitis was the most common cause of persistent epithelial defects (58.8%), and within this category, herpetic eye disease was the main comorbidity (44.4%). The mean follow-up time was 17.91 months. …”
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112
MD-Unet for tobacco leaf disease spot segmentation based on multi-scale residual dilated convolutions
Published 2025-01-01“…To address the limitations of traditional methods, such as weak generalization and sensitivity to noise in segmenting tobacco leaf lesions, this study focused on four tobacco diseases: angular leaf spot, brown spot, wildfire disease, and frog eye disease. Building upon the Unet architecture, we developed the Multi-scale Residual Dilated Segmentation Model (MD-Unet) by enhancing the feature extraction module and integrating attention mechanisms. …”
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113
Short-Term Effects of a Novel Eye Mask Producing Heat and Vibration for the Treatment of Meibomian Gland Dysfunction: A Pilot Study
Published 2021-01-01“…To investigate the short-term effects on tear film parameters and ocular symptoms of a novel eye mask producing heat and vibration developed for the treatment of dry eye disease owing to meibomian gland dysfunction (MGD). …”
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114
A Korean Patient With Leber Congenital Amaurosis and a Homozygous RPE65 Variant Originating From a Paternal Uniparental Isodisomy
Published 2025-01-01“…ABSTRACT Background Leber congenital amaurosis (LCA), the most severe form of inherited retinal dystrophy, is a rare, heterogeneous, genetic eye disease associated with severe congenital visual impairment. …”
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115
Comparative Evaluation of Tear Film and Corneal Surface in Chronic Smokers and Non Smokers: A Cross-sectional Study
Published 2025-01-01“…Tobacco smoke is a well-documented ocular irritant that exacerbates Dry Eye Disease (DED) and its associated symptoms. Aim: To compare tear film and corneal surface parameters in chronic smokers and non smokers. …”
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116
Change in Ocular Surface Staining during Eyelid Warming Is Related to Tear Cytokine Levels
Published 2022-01-01“…To investigate the changes in the tear cytokine profile of patients with meibomian gland dysfunction (MGD) treated with eyelid warming and to correlate these changes with clinical parameters for dry eye disease (DED). Methods. Seventy patients with MGD were included and treated with the warming of eyelids. …”
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117
Extracellular MMP-9-Based Assessment of Ocular Surface Inflammation in Patients with Primary Open-Angle Glaucoma
Published 2019-01-01“…Objective assessment of dry eye disease (DED) severity and ocular inflammation using the InflammaDry® test for extracellular matrix metalloproteinase-9 (MMP-9) and the impact of antiglaucoma eye drops in people with primary open-angle glaucoma (POAG). …”
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118
Anatomical and Visual Outcomes after LASIK Performed in Myopic Eyes with the WaveLight® Refractive Suite (Alcon® Laboratories Inc., USA)
Published 2020-01-01“…Besides, we can assume that the patients’ quality of vision depends more on the postoperative dry eye disease generated by the laser than on the induced HOAs.…”
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119
Unveiling molecular insights: in silico exploration of TLR4 antagonist for management of dry eye syndrome
Published 2024-05-01“…Background Dry eye disease is the most commonplace multifractional ocular complication, which has already affected millions of people in the world. …”
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120
TACSTD2 in gelatinous drop-like corneal dystrophy: variant functional analysis and expression in the cornea after limbal stem cell transplantation
Published 2024-07-01“…Abstract Gelatinous drop-like corneal dystrophy (GDLD) is a rare autosomal recessive eye disease. GDLD is characterized by the loss of barrier function in corneal epithelial cells (CECs) and amyloid deposition due to pathogenic variants in the TACSTD2 gene. …”
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