Macrophages in sepsis-induced acute lung injury: exosomal modulation and therapeutic potential by Kaiying Lv, Qun Liang

“…Exosomes, small extracellular vesicles released by various cells, carry bioactive molecules that influence macrophage polarization and immune responses. …”
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Emerging role of exosomes in cancer therapy: progress and challenges by Jiale Li, Jiachong Wang, Zigui Chen

“…Abstract This review highlights recent progress in exosome-based drug delivery for cancer therapy, covering exosome biogenesis, cargo selection mechanisms, and their application across multiple cancer types. As small extracellular vesicles, exosomes exhibit high biocompatibility and low immunogenicity, making them ideal drug delivery vehicles capable of efficiently targeting cancer cells, minimizing off-target damage and side effects. …”
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The Role of Mesenchymal Stem Cell Secretome (Extracellular Microvesicles and Exosomes) in Animals’ Musculoskeletal and Neurologic-Related Disorders by Alefe Luiz Caliani Carrera, Bruno Watanabe Minto, Patrícia Malard, Hilana dos Santos Sena Brunel

“…The use of those cells, as well as recent advances related to the use of their extracellular vesicles, demonstrates a great opportunity to enhance therapeutic methods and ensure more life quality for patients, which can be in clinical or surgical treatments. …”
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Determination of Protein Amount in Nanosized Synthetic Liposomes by Surface Effect Raman Spectroscopy (SERS) by Şeyma Parlatan

“…Accurate characterization of synthetic liposomes is essential since they give information about the vesicu-lar structures in bodily fluids such as extracellular vesicles. The characterization tasks are generally the determination of the sizes of the liposomes and the profiling of the liposomes' content. …”
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The Crosstalk between Ovarian Cancer Stem Cell Niche and the Tumor Microenvironment by Manuel Varas-Godoy, Gregory Rice, Sebastián E. Illanes

“…This interaction can be mediated by cytokines, growth factors, lipids, and/or extracellular vesicles released in the CSC niche. In this review, we will discuss how the interaction between ovarian CSCs and the tumor microenvironment can contribute to the maintenance of the CSC niche and consequently to tumor progression in ovarian cancer.…”
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Advance of Mesenchymal Stem Cells in Chronic End-Stage Liver Disease Control by Yun Gao, Xiushan Yin, Xiaomeng Ren

“…MSCs can secrete a large number of cytokines, chemokines, immunomodulatory molecules, and hepatotrophic factors, as well as produce extracellular vesicles. They alleviate liver diseases by differentiating to hepatocyte-like cells, immunomodulation, homing to the injured site, regulating cell ferroptosis, regulating cell autophagy, paracrine effects, and MSC-mitochondrial transfer. …”
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A New Paradigm in Cardiac Regeneration: The Mesenchymal Stem Cell Secretome by Clara Gallina, Valentina Turinetto, Claudia Giachino

“…We provide insights into the possible employment of the MSCs secretome and their released extracellular vesicles as novel approaches for cardiac regeneration that would have certain advantages over injection of living cells.…”
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Insights into Cancer-Associated Thrombosis Leading Towards Ischemic Stroke by Surajit Hansda, Hiranmoy Das

“…Atherosclerosis, extracellular vesicles (EVs), and signaling biomolecules can also affect CAS. …”
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Golgi-restored vesicular replenishment retards bone aging and empowers aging bone regeneration by Peisheng Liu, Hao Guo, Xiaoyao Huang, Anqi Liu, Ting Zhu, Chenxi Zheng, Fei Fu, Kaichao Zhang, Shijie Li, Xinyan Luo, Jiongyi Tian, Yan Jin, Kun Xuan, Bingdong Sui

“…Interestingly, replenishment of cell aggregates-derived extracellular vesicles (CA-EVs) rescues Golgi dysfunction and empowers senescent MSCs through the Golgi regulatory protein Syntaxin 5. …”
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Brain injury biomarkers and applications in neurological diseases by Han Zhang, Jing Wang, Yang Qu, Yi Yang, Zhen-Ni Guo, Yanjie Yin

“…In this review, we described biomarkers for neuronal cell body injury (neuron-specific enolase, ubiquitin C-terminal hydrolase-L1, αII-spectrin), axonal injury (neurofilament proteins, tau), astrocyte injury (S100β, glial fibrillary acidic protein), demyelination (myelin basic protein), autoantibodies, and other emerging biomarkers (extracellular vesicles, microRNAs). We aimed to summarize the applications of these biomarkers and their related interests and limits in the diagnosis and prognosis for neurological diseases, including traumatic brain injury, status epilepticus, stroke, Alzheimer’s disease, and infection. …”
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Micro-channels array device fabricated via two photon lithography for cell migration studies in Neuroblastoma metastatic disseminationAll original data are available at: . by Sara Micheli, Caterina Piunti, Elisa Varaschin, Marianna Peditto, Maria Luz Suarez, Marco Sorgato, Elisa Cimetta

“…Pre-exposure of MSCs to NB-derived extracellular vesicles (EVs) significantly increased their motility towards tumor cells. …”
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Neuropilin1-dependent paracrine signaling of cancer cells mediated by miRNA exosomal cargo by Claudia Palazzo, Roberta Mastrantonio, Noemi Gioelli, Erika Testa, Francesco Recco, Donatella Lucchetti, Giulia Villari, Alessio D’Alessio, Alessandro Sgambato, Flavio Mignone, Guido Serini, Maria Teresa Viscomi, Luca Tamagnone

“…Notably, diffusible forms of NRP1 in the extracellular space have been reported, but their functional role is poorly understood. Methods Extracellular vesicles (EV) were isolated from conditioned media of diverse cancer cells. …”
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Exosomes in Oral Diseases: Mechanisms and Therapeutic Applications by Miao Q, Li S, Lyu W, Zhang J, Han Y

“…Qiandai Miao, Shaoqing Li, Weijia Lyu, Jianxia Zhang, Yan Han Department of Stomatology, China Academy of Chinese Medical Sciences, Xiyuan Hospital, Beijing, 100091, People’s Republic of ChinaCorrespondence: Yan Han, Email hy1352111@163.comAbstract: Exosomes, small extracellular vesicles secreted by various cells, play crucial roles in the pathogenesis and treatment of oral diseases. …”
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Recent progress in prompt molecular detection of liquid biopsy using Cas enzymes: innovative approaches for cancer diagnosis and analysis by Zahra Farshchian Yazdi, Shahrzad Roshannezhad, Samaneh Sharif, Mohammad Reza Abbaszadegan

“…Analyzing the nucleic acid content of liquid biopsy samples, which include Circulating Tumor Cells (CTCs), Circulating Tumor DNA (ctDNA), Circulating Cell-Free RNA (cfRNA), and tumor extracellular vesicles, provides a noninvasive method for cancer detection and monitoring. …”
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Exosomes, their sources, and possible uses in cancer therapy in the era of personalized medicine by Tomas Zemanek, Lubos Danisovic, Andreas Nicodemou

“…Exosomes, a primary type of extracellular vesicles, can transport diverse intracellular molecules to nearby or distant cells and organs, facilitating numerous biological functions. …”
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Noble Metal Nanoparticle‐Based Aptasensors: A Powerful Tool for Exosomal Detection by Jingyu Sun, Wei Hu, Nuo Xu, Jonathan Makris, Felicia Spadavecchia, Hongjun Wang

“…In this review, the progress will summarized in exosomes as a biomarker for diseases and the recent advances in the use of noble metal nanoparticle/aptamer‐based sensors for analysis of exosomes and other extracellular vesicles.…”
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Exosome-Like Vesicles as New Mediators and Therapeutic Targets for Treating Insulin Resistance and β-Cell Mass Failure in Type 2 Diabetes Mellitus by Qian Ge, Xin Xin Xie, Xiaoqiu Xiao, Xi Li

“…Exosome-like vesicles (ELVs), the smallest class of extracellular vesicles released from cells, function in cellular crosstalk and therefore profoundly affect physiologic responses and pathologic progression. …”
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Myocardial Regeneration via Progenitor Cell-Derived Exosomes by Janita A. Maring, Christien M. Beez, Volkmar Falk, Martina Seifert, Christof Stamm

“…Recently, a subset of small extracellular vesicles (EVs), commonly referred to as “exosomes,” was shown to confer cardioprotective and regenerative signals at a magnitude similar to that of their donor cells. …”
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<i>Akkermansia muciniphila</i>: A Potential Target for the Prevention of Diabetes by Kairu He, Feiyu An, Henan Zhang, Danli Yan, Tong Li, Junrui Wu, Rina Wu

“…Thus, <i>A. muciniphil</i> and its components, including the outer membrane protein Amuc_1100, <i>A. muciniphila</i>-derived extracellular vesicles (AmEVs), and the secreted proteins P9 and Amuc_1409, are systematically summarized with respect to mechanisms of action in diabetes mellitus. …”
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Diagnostic and Prognostic Significance of Exosomes and Their Components in Patients With Cancers by Zinnat Ara Moni, Zahid Hasan, Md. Shaheen Alam, Nitai Roy, Farhadul Islam

“…ABSTRACT Background Cancer is the second leading cause of human mortality worldwide. Extracellular vesicles (EVs) from liquid biopsy samples are used in early cancer detection, characterization, and surveillance. …”
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