A protocol for loading Calcein-AM into extracellular vesicles from mammalian cells for clear visualization with a fluorescence microscope coupled to a deconvolution system. by María-Angélica Calderón-Peláez, Jaime E Castellanos, Myriam L Velandia-Romero

“…Extracellular vesicles (EVs) are membrane-bound structures produced and released into the extracellular space by all types of cells. …”
Get full text

Fused extracellular vesicles from M2 macrophages and human umbilical cord mesenchymal stem cells for the targeted regulation of macrophage pyroptosis in periprosthetic osteolysis by Qimeng Liu, Tianliang Ma, Zheyu Zhang, Jiangyu Nan, Guanzhi Liu, Yute Yang, Yihe Hu, Jie Xie

Subjects: Get full text

Composition Analysis of Airborne Microbiota in Outdoor and Indoor Based on Dust Separated by Micro-sized and Nano-sized by Jinho Yang, Ji-Hoon Seo, Young-Koo Jee, Yoon-Keun Kim, Jong-Ryeul Sohn

Subjects: Get full text

Extracellular Vesicles Derived from Human Umbilical Mesenchymal Stem Cells Transfected with miR-7704 Improved Damaged Cartilage and Reduced Matrix Metallopeptidase 13 by Kun-Chi Wu, Hui-I Yang, Yu-Hsun Chang, Raymond Yuh-Shyan Chiang, Dah-Ching Ding

Subjects: “…extracellular vesicles…”
Get full text

Small Extracellular Vesicles Derived from Human Umbilical Cord Mesenchymal Stem Cells Enhanced Proangiogenic Potential of Cardiac Fibroblasts via Angiopoietin-Like 4 by Jiejie Li, Xin Xu, Suyan Fei, Ren Wang, Hua Wang, Wei Zhu, Yuanyuan Zhao

“…Previous studies have suggested that cardiac fibroblasts (CFs) play a crucial role in angiogenesis after myocardial injury. Small extracellular vesicles (sEVs) derived from human umbilical cord mesenchymal stem cells (hucMSCs) promote fibroblast-to-myofibroblast differentiation in inflammatory environment and have cardioprotective effects. …”
Get full text

Hypoxia-Elicited Mesenchymal Stem Cell-Derived Small Extracellular Vesicles Alleviate Myocardial Infarction by Promoting Angiogenesis through the miR-214/Sufu Pathway by Lianbo Shao, Yihuan Chen, Jingjing Li, Jingfan Chao, Ziying Yang, Yinglong Ding, Han Shen, Yueqiu Chen, Zhenya Shen

“…In our study, we preconditioned human umbilical cord mesenchymal stem cells (huMSCs) with hypoxia and isolated the small extracellular vesicles (sEVs) to promote cardiac repair. We also investigated the potential mechanisms. …”
Get full text

Folic acid-modified ginger-derived extracellular vesicles for targeted treatment of rheumatoid arthritis by remodeling immune microenvironment via the PI3K-AKT pathway by Ruina Han, Dongyang Zhou, Ning Ji, Zhifeng Yin, Jian Wang, Qin Zhang, Hao Zhang, Jinlong Liu, Xinru Liu, Han Liu, Qinglin Han, Jiacan Su

Subjects: “…Plant-derived extracellular vesicles…”
Get full text

Global research landscape and emerging trends of non-coding RNAs in prostate cancer: a bibliometric analysis by Yu-Liang Zhou, Yu-Liang Zhou, Wen-Liang Yao, Wen-Liang Yao, Sheng-Hui Chen, Sheng-Hui Chen, Peng Wang, Peng Wang, Jing-Wen Fu, Jing-Wen Fu, Jia-Qin Zhao, Jia-Qin Zhao, Jia-Yi Zhang, Jia-Yi Zhang

Subjects: Get full text

Retracted: Adipose-Derived Mesenchymal Stem Cell-Derived Extracellular Vesicles Rescue Tendon Injury in Rat via the miR-19 a/IGFBP3 Axis by Stem Cells International

Get full text

Stabilizing milk-derived extracellular vesicles (mEVs) through lyophilization: a novel trehalose and tryptophan formulation for maintaining structure and Bioactivity during long-term storage by Alan B. Dogan, Spencer R. Marsh, Rachel J. Tschetter, Claire E. Beard, Md R. Amin, L. Jane Jourdan, Robert G. Gourdie

Subjects: Get full text

Extracellular Vesicles Released from Neprilysin Gene-Modified Human Umbilical Cord-Derived Mesenchymal Stem Cell Enhance Therapeutic Effects in an Alzheimer’s Disease Animal Model by HyeJu Jeong, Ok Joon Kim, Seung-Hun Oh, Sanghoon Lee, Han A. Reum Lee, Kee Ook Lee, Boo-Yong Lee, Nam Keun Kim

“…After stem cell injection, stem cells were not found. Extracellular vesicles (EVs) were equally observed in the hippocampus in the naïve and NEP-enhanced hUC-MSC groups. …”
Get full text

Clinical-grade extracellular vesicles derived from umbilical cord mesenchymal stromal cells: preclinical development and first-in-human intra-articular validation as therapeutics for knee osteoarthritis by Aliosha I. Figueroa-Valdés, Patricia Luz-Crawford, Yeimi Herrera-Luna, Nicolás Georges-Calderón, Cynthia García, Hugo E. Tobar, María Jesús Araya, José Matas, Darío Donoso-Meneses, Catalina de la Fuente, Jimena Cuenca, Eliseo Parra, Fernando Lillo, Cristóbal Varela, María Ignacia Cádiz, Rolando Vernal, Alexander Ortloff, Gino Nardocci, Verónica Castañeda, Catalina Adasme-Vidal, Maximiliano Kunze-Küllmer, Yessia Hidalgo, Francisco Espinoza, Maroun Khoury, Francisca Alcayaga-Miranda

Subjects: “…Small extracellular vesicles…”
Get full text

Exosomes in oral squamous cell carcinoma: functions, challenges, and potential applications by Bo Zhao, Bo Zhao, Zuntai Li, Ronghua Li

Subjects: “…extracellular vesicles…”
Get full text

Attempts to preserve and visualize protein corona on the surface of biological nanoparticles in blood serum using photomodification by Julia E. Poletaeva, Anastasiya V. Tupitsyna, Alina E. Grigor’eva, Ilya S. Dovydenko, Elena I. Ryabchikova

Subjects: Get full text

TNF-α Enhances the Therapeutic Effects of MenSC-Derived Small Extracellular Vesicles on Inflammatory Bowel Disease through Macrophage Polarization by miR-24-3p by Huikang Xu, Jiamin Fu, Lijun Chen, Sining Zhou, Yangxin Fang, Qi Zhang, Xin Chen, Li Yuan, Yifei Li, Zhenyu Xu, Charlie Xiang

“…Human menstrual blood-derived mesenchymal stem cells (MenSCs) and their secreted small extracellular vesicles (EVs) had been proven to relieve inflammation, tissue damage, and fibrosis in various organs. …”
Get full text

Bone marrow mesenchymal stem cell-derived extracellular vesicles alleviate diabetes-exacerbated atherosclerosis via AMPK/mTOR pathway-mediated autophagy-related macrophage polarization by Libo Liu, Ziyu An, Huan Zhang, Xueqi Wan, Xin Zhao, Xueyao Yang, Jinfan Tian, Xiantao Song

Subjects: “…Bone marrow mesenchymal stem cell-derived extracellular vesicles…”
Get full text

Human endometrial stem cell-derived small extracellular vesicles enhance neurite outgrowth and peripheral nerve regeneration through activating the PI3K/AKT signaling pathway by Mojdeh Salehi Namini, Nima Beheshtizadeh, Somayeh Ebrahimi-Barough, Jafar Ai

“…Abstract Nowadays, extracellular vesicles (EVs) such as exosomes participate in cell-cell communication and gain attention as a new approach for cell-free therapies. …”
Get full text

Extracellular vesicles in seminal plasma of Sahiwal cattle bulls carry a differential abundance of sperm fertility-associated proteins for augmenting the functional quality of low-fertile bull spermatozoa by Ankit Pal, Seema Karanwal, Mir Ahmad Habib, Fanny Josan, Vikrant Gaur, Aditya Patel, Muskaan Garg, Mukesh Bhakat, Tirtha K. Datta, Rakesh Kumar

Subjects: Get full text

Small Extracellular Vesicles Secreted by iPSC-Derived MSCs Ameliorate Pulmonary Inflammation and Lung Injury Induced by Sepsis through Delivery of miR-125b-5p by Wei Peng, Yun Yang, Jiaquan Chen, Zeyao Xu, Yuanlei Lou, Qi Li, Ning Zhao, Kejian Qian, Fen Liu

“…Sepsis-induced acute lung injury is a common critical illness in intensive care units with no effective treatment is currently available. Small extracellular vesicles, secreted by mesenchymal stem cells (MSCs), derived from human-induced pluripotent stem cells (iMSC-sEV), possess striking advantages when incorporated MSCs and iPSCs, which are considered extremely promising cell-free therapeutic agents. …”
Get full text

Identifying plasma exosome antigens as a potential diagnostic biomarker for tuberculosis disease by Yan Jiang, Li Yan, Baoru Zhou, Jianming Hong, Huixing Tan, Xiaonan Li, Yong Wang

Subjects: Get full text