Phenotypic and Functional Changes of Endothelial and Smooth Muscle Cells in Thoracic Aortic Aneurysms by Anna Malashicheva, Daria Kostina, Aleksandra Kostina, Olga Irtyuga, Irina Voronkina, Larisa Smagina, Elena Ignatieva, Natalia Gavriliuk, Vladimir Uspensky, Olga Moiseeva, Jarle Vaage, Anna Kostareva

“…Cellular proliferation, migration, and synthesis of extracellular matrix proteins are attenuated in the cells of the patients. …”
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Novel Artificial Biofilm Equivalent for Denture Surfaces: A Pilot Study by Jan-Philipp Kunze, Klaus Boening, Heike Meissner, Katarzyna Kresse-Walczak

“…The microbial population of the dental biofilm is embedded in an extracellular matrix that contains organic polymers such as polysaccharides. …”
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The comprehensive assessment of epigenetics changes during skin development by Li Lei, Ling Jiang, Yibo Hu, Menglu Chen, Jinhua Huang, Jing Chen, Qinghai Zeng

“…Epigenetic effectors such as IGF2BP2, GATA2, GATA3, CPA4 and CDK1 were significantly correlated with extracellular matrix organization, and VEGFA, CDK1 and PRKCB with skin immune function. …”
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Engineering a Biocompatible Scaffold with Either Micrometre or Nanometre Scale Surface Topography for Promoting Protein Adsorption and Cellular Response by Xuan Le, Gérrard Eddy Jai Poinern, Nurshahidah Ali, Cassandra M. Berry, Derek Fawcett

“…The nanometre-structured surface features tend to resemble the extracellular matrix, the natural environment in which cells live, communicate, and work together. …”
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The Role of Decorin in Autoimmune and Inflammatory Diseases by Yuanji Dong, Jixin Zhong, Lingli Dong

“…Decorin is an extracellular matrix protein that belongs to the family of small leucine-rich proteoglycans. …”
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Role of Matrix Metalloproteinases in Angiogenesis and Its Implications in Asthma by Khuloud Bajbouj, Rakhee K. Ramakrishnan, Qutayba Hamid

“…In addition to facilitating extracellular matrix turnover, these proteolytic enzymes cleave bioactive molecules, thereby regulating cell signaling. …”
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Novel Nanomaterials Enable Biomimetic Models of the Tumor Microenvironment by Marshall Hunter Joyce, Shane Allen, Laura Suggs, Amy Brock

“…In the complex tumor microenvironment, chemical and mechanical signals from tumor cells, stromal cells, and the surrounding extracellular matrix influence all aspects of disease progression and response to treatment. …”
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Alpha Lipoic Acid Modulated High Glucose-Induced Rat Mesangial Cell Dysfunction via mTOR/p70S6K/4E-BP1 Pathway by Chuan Lv, Can Wu, Yue-hong Zhou, Ying Shao, Guan Wang, Qiu-yue Wang

“…The aim of this study was to investigate whether alpha lipoic acid (LA) regulates high glucose-induced mesangial cell proliferation and extracellular matrix production via mTOR/p70S6K/4E-BP1 signaling. …”
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Cellular Origins of Regenerating Nodules and Malignancy in the FAH Model of Liver Injury after Bone Marrow Cell Transplantation by Pei-Rong Wang, Yi Li

“…There was higher expression of extracellular matrix proteins and more inflammatory cells in liver tumor nodules than in regenerating normal liver nodules. …”
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Timp2 loss-of-function mutation and TIMP2 treatment in a murine model of NSCLC: Modulation of immunosuppression and oncogenic signaling by David Peeney, Sarvesh Kumar, Tej Pratap Singh, Yueqin Liu, Sandra M. Jensen, Ananda Chowdhury, Sasha Coates-Park, Joshua Rich, Sadeechya Gurung, Yu Fan, Daoud Meerzaman, William G. Stetler-Stevenson

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Electrospun Nanostructured Fibers of Collagen-Biomimetic Apatite on Titanium Alloy by Michele Iafisco, Ismaela Foltran, Simona Sabbatini, Giorgio Tosi, Norberto Roveri

“…., bone implant contact) can be obtained by the application of a material that mimics the bone extracellular matrix. To this aim, this work describes a new method to produce nanostructured collagen-apatite composites on titanium alloy substrate, by combining electrospinning and biomimetic mineralization. …”
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Fibrin and Collagen Differentially but Synergistically Regulate Sprout Angiogenesis of Human Dermal Microvascular Endothelial Cells in 3-Dimensional Matrix by Xiaodong Feng, Marcia G. Tonnesen, Shaker A. Mousa, Richard A. F. Clark

“…Angiogenesis is a highly regulated event involving complex, dynamic interactions between microvascular endothelial cells and extracellular matrix (ECM) proteins. Alteration of ECM composition and architecture is a hallmark feature of wound clot and tumor stroma. …”
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Polymeric Scaffolds in Tissue Engineering Application: A Review by Brahatheeswaran Dhandayuthapani, Yasuhiko Yoshida, Toru Maekawa, D. Sakthi Kumar

“…In recent years, considerable interest has been given to biologically active scaffolds which are based on similar analogs of the extracellular matrix that have induced synthesis of tissues and organs. …”
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LPS Counter Regulates RNA Expression of Extracellular Proteases and Their Inhibitors in Murine Macrophages by Andreas Hald, Birgitte Rønø, Leif R. Lund, Kristoffer L. Egerod

“…Regardless of the exact situation, macrophage activation and migration are intimately connected to extracellular matrix degradation. This process is accomplished by multiple proteolytic enzymes, including serine proteases and members of the matrix metalloproteinase family. …”
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Genetic analysis of pathways regulated by the von Hippel-Lindau tumor suppressor in Caenorhabditis elegans. by Tammie Bishop, Kah Weng Lau, Andrew C R Epstein, Stuart K Kim, Min Jiang, Delia O'Rourke, Christopher W Pugh, Jonathan M Gleadle, Martin S Taylor, Jonathan Hodgkin, Peter J Ratcliffe

“…Genomic clustering, predicted functional similarities, and a common pattern of dysregulation in both vhl-1 worms and a set of mutants (dpy-18, let-268, gon-1, mig-17, and unc-6), with different defects in extracellular matrix formation, suggest that dysregulation of these genes reflects a discrete HIF-1-independent function of VHL-1 that is connected with extracellular matrix function.…”
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Biochemistry of Bacterial Biofilm: Insights into Antibiotic Resistance Mechanisms and Therapeutic Intervention by Kashish Azeem, Sadaf Fatima, Asghar Ali, Ayesha Ubaid, Fohad Mabood Husain, Mohammad Abid

“…Biofilms, composed of structured communities of bacteria embedded in a self-produced extracellular matrix, pose a significant challenge due to their heightened resistance to antibiotics and immune responses. …”
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Plasma and Aorta Biochemistry and MMPs Activities in Female Rabbit Fed Methionine Enriched Diet and Their Offspring by Khira Othmani Mecif, Souhila Aouichat Bouguerra, Yasmina Benazzoug

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Soft X-ray tomography reveals variations in B. subtilis biofilm structure upon tasA deletion by Anthoula Chatzimpinou, Anne Diehl, A. Tobias Harhoff, Kristina Driller, Bieke Vanslembrouck, Jian-Hua Chen, Kristaps Kairišs, Valentina Loconte, Mark A. Le Gros, Carolyn Larabell, Kürşad Turgay, Hartmut Oschkinat, Venera Weinhardt

“…Abstract Bacterial biofilms are complex cell communities within a self-produced extracellular matrix, crucial in various fields but challenging to analyze in 3D. …”
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Magnesium Oxide Nanoparticles Reinforced Electrospun Alginate-Based Nanofibrous Scaffolds with Improved Physical Properties by R. T. De Silva, M. M. M. G. P. G. Mantilaka, K. L. Goh, S. P. Ratnayake, G. A. J. Amaratunga, K. M. Nalin de Silva

“…Mechanically robust alginate-based nanofibrous scaffolds were successfully fabricated by electrospinning method to mimic the natural extracellular matrix structure which benefits development and regeneration of tissues. …”
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RNAI-MEDIATED SILENCING OF MATRIX METALLOPROTEINASE 1 IN EPIDERMAL KERATINOCYTES INFLUENCES THE BIOLOGICAL EFFECTS OF INTERLEUKIN 17A by J. A. Mogulevtseva, A. V. Mezentsev, S. A. Bruskin

“…MMPs change the composition and other properties of the extracellular matrix. These changes facilitate tissue remodeling and promote the development of psoriatic plaques. …”
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