Impact of Extracellular Matrix-Related Genes on the Tumor Microenvironment and Prognostic Indicators in Esophageal Cancer: A Comprehensive Analytical Study by Yinghong Wu, Wenjie Hu, Zhihong Jia, Qiying Zhu, Jinghui Xu, Liang Peng, Renjie Wang

“…Recent studies underscore the extracellular matrix (ECM) role in cancer progression, but the full impact of ECM-related genes on patient outcomes remains unclear. …”
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FIRM image analysis: A machine learning workflow for quantifying extracellular matrix components from electron microscopy images. by Nicholas T Gigliotti, Justin Lee, Emily H Mang, Giancarlo R Zambrano, Mitra L Taheri

“…The extracellular matrix (ECM) is a complex network of biomolecules that plays an integral role in the structure, processes, and signaling mechanisms of cells and tissues. …”
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Hydrostatic Pressure Modulates Intervertebral Disc Cell Survival and Extracellular Matrix Homeostasis via Regulating Hippo-YAP/TAZ Pathway by Yiyang Wang, Baoshuai Bai, Yanzhu Hu, Haoming Wang, Ningyuan Liu, Yibo Li, Pei Li, Guangdong Zhou, Qiang Zhou

“…Results revealed that low-loading dynamic hydrostatic pressure was beneficial for cell survival and extracellular matrix (ECM) homeostasis in notochordal NP and fibrocartilaginous inner AF via upregulating N-cadherin (N-CDH) and integrin β1. …”
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Human embryonic stem cells cultured on hydrogels grafted with extracellular matrix protein‐derived peptides with polyethylene glycol joint nanosegments by Abdullah A. Alarfaj, Abdurahman H. Hirad, Murugan A. Munusamy, S. Suresh Kumar, Akon Higuchi

“…Abstract Human pluripotent stem cells (hPSCs) can be proliferated on completely synthetic materials under xeno‐free cultivation conditions using biomaterials grafted with extracellular matrix protein (ECM)‐derived peptides. However, cell culture biomaterials grafted with ECM‐derived peptides must be prepared using a high concentration of peptide reaction solution (e.g. 1000 μg/ml), whereas the ECM concentration of the ECM‐coated surface for hPSC culture is typically 5 μg/ml. …”
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Collagen turnover biomarkers to predict outcome of patients with biliary cancer by Leonard Kaps, Muhammed A. Genc, Markus Moehler, Stephan Grabbe, Jörn M. Schattenberg, Detlef Schuppan, Rasmus Sund Pedersen, Morten A. Karsdal, Philipp Mildenberger, Annett Maderer, Nicholas Willumsen

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Skip Regulates TGF-β1-Induced Extracellular Matrix Degrading Proteases Expression in Human PC-3 Prostate Cancer Cells by Victor Villar, Jelena Kocic, Juan F. Santibanez

“…Thus, SKIP is implicated in the regulation of extracellular matrix degradation and can therefore be suggested as a novel therapeutic target in prostate cancer treatment.…”
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Optimizations of Placenta Extracellular Matrix‐Loaded Silk Fibroin/Alginate 3D‐Printed Scaffolds Structurally and Functionally for Bone Tissue Engineering by Zahra Bashiri, Zahra Khosrowpour, Ali Moghaddaszadeh, Davod Jafari, Sanaz Alizadeh, Hajar Nasiri, Houman Parsaei, Zahra Keshtkaran, Meghdad Abdollahpour‐Alitappeh, Farshad Bargrizaneh, Behzad Rezaei, Sara Simorgh, Mazaher Gholipourmalekabadi

“…ABSTRACT Recent interest has been focused on extracellular matrix (ECM)–based scaffolds totreat critical‐sized bone injuries. …”
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Gut microbiome diversity as adjuvant marker for immune function by Mahdaleny, Febriana Catur Iswanti

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Nephronectin Is Required for Vascularization in Zebrafish and Sufficient to Promote Mammalian Vessel‐Like Structures in Hydrogels for Tissue Engineering by Chinmoy Patra, Amey Rayrikar, Ganesh Wagh, Florian Kleefeldt, Kaveh Roshanbinfar, Florian Cop, Iva Nikolic, Mirko H. H. Schmidt, Amparo Acker‐Palmer, Süleyman Ergün, Felix B. Engel

Subjects: “…extracellular matrix…”
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lncRNA DLEU1 Modulates Proliferation, Inflammation, and Extracellular Matrix Degradation of Chondrocytes through Regulating miR-671-5p by Xiangkun Wu, Shuai Yin, Lihua Yan, Yongxi Liu, Lilin Shang, Jun Liu

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The PI3K/Akt Signaling Pathway Mediates the High Glucose-Induced Expression of Extracellular Matrix Molecules in Human Retinal Pigment Epithelial Cells by Dong Qin, Guo-ming Zhang, Xun Xu, Li-ya Wang

“…Prolonged hyperglycemia is an important risk factor of the pathogenesis of diabetic retinopathy (DR). Extracellular matrix molecules, such as fibronectin, collagen IV, and laminin, are associated with fibrotic membranes. …”
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Combining extracellular matrix proteome and phosphoproteome of chickpea and meta‐analysis reveal novel proteoforms and evolutionary significance of clade‐specific wall‐associated events in plant by Kanika Narula, Arunima Sinha, Pooja Choudhary, Sudip Ghosh, Eman Elagamey, Archana Sharma, Atreyee Sengupta, Niranjan Chakraborty, Subhra Chakraborty

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Edaravone dexborneol alleviates pericyte-mediated fibrosis depositing extracellular matrix through TGF-β1/IL-11 in cerebral small vessel disease by Qingrui Duan, Zhiyang Liu, Yuxuan Xing, Haifeng Huang, Lin Zhu, Jiaxuan Liu, Peikun He, Guixian Ma, Yuhu Zhang, Kun Nie, Yuyuan Gao, Lijuan Wang

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Golgin Subfamily A Member 5 Is Essential for Production of Extracellular Matrix Proteins during TGF-β1-Induced Periodontal Ligament-Fibroblastic Differentiation by Hyun-Jin Kim, Seong-Min Kim, Min-Jeong Choi, Young-Joo Jang

“…When the TGF-β1 signaling pathway was blocked or GOLGA5 was depleted by siRNA, the levels of extracellular matrix (ECM) proteins, such as type I collagen and fibronectin, decreased in PDL-fibroblastic progenitors. …”
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Effectiveness of Voytik-Harbin Protocol in Fabrication of Ram’s Testicular-Derived Hydrogel and Its Impact on Mouse In Vitro Spermatogenesis by Leila Rashki Ghaleno, Tohid Rezaei Topraggaleh, Leila Montazeri, Abdolhossein Shahverdi, Mojtaba Rezazadeh Valojerdi

Subjects: “…decellularized extracellular matrix…”
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High Glucose-Induced Oxidative Stress Mediates Apoptosis and Extracellular Matrix Metabolic Imbalances Possibly via p38 MAPK Activation in Rat Nucleus Pulposus Cells by Xiaofei Cheng, Bin Ni, Feng Zhang, Ying Hu, Jie Zhao

“…To investigate whether high glucose-induced oxidative stress is implicated in apoptosis of rat nucleus pulposus cells (NPCs) and abnormal expression of critical genes involved in the metabolic balance of extracellular matrix (ECM). Methods. NPCs were cultured with various concentrations of glucose to detect cell viability and apoptosis. …”
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Cardiac-Restricted IGF-1Ea Overexpression Reduces the Early Accumulation of Inflammatory Myeloid Cells and Mediates Expression of Extracellular Matrix Remodelling Genes after Myocardial Infarction by Enrique Gallego-Colon, Robert D. Sampson, Susanne Sattler, Michael D. Schneider, Nadia Rosenthal, Joanne Tonkin

“…This correlates with reduced extracellular matrix remodelling and changes in collagen composition that may confer enhanced scar elasticity and improved cardiac function.…”
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Xenoimplantation of an Extracellular-Matrix-Derived, Biphasic, Cell-Scaffold Construct for Repairing a Large Femoral-Head High-Load-Bearing Osteochondral Defect in a Canine Model by Yang Qiang, Zhao Yanhong, Peng Jiang, Lu Shibi, Guo Quanyi, Ma Xinlong, Xia Qun, Xu Baoshan, Zhao Bin, Wang Aiyuan, Zhang Li, Xu Wengjing, Zeng Chao

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miR-486-5p Restrains Extracellular Matrix Production and Oxidative Damage in Human Trabecular Meshwork Cells by Targeting TGF-β/SMAD2 Pathway by Le Xu, Yiming Zhang, Hua Long, Bo Zhou, Haibo Jiang

“…TMCs were disposed with 300 μM H2O2 to establish oxidative damage models in vitro. miR-486-5p mimics and its controls were transfected into TMCs, and cell apoptosis and extracellular matrix production (ECM) genes were measured by flow cytometry, western blotting, and immunofluorescence staining. …”
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Matrix metalloproteinase-3 is a potent prognostic factor associated with cell proliferation and migration in prostate cancer by Ai Sato, Kiyoshi Takagi, Mio Yamaguchi-Tanaka, Jotaro Okushima, Yuto Yamazaki, Akihiro Ito, Takashi Suzuki

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