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Exosome-based targeted delivery of NF-κB ameliorates age-related neuroinflammation in the aged mouse brain
Published 2025-01-01“…Thus, our findings highlight Exo-srIκB as a potential therapeutic agent for treating age-related neuroinflammation.…”
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A Sensitive Fluorescence Biosensor for Silver Ions (Ag+) Detection Based on C-Ag+-C Structure and Exonuclease III-Assisted Dual-Recycling Amplification
Published 2019-01-01“…A C-Ag+-C structure-based fluorescence biosensor with novel combination design of exonuclease III (Exo III) dual-recycling amplification is proposed for the application of silver ions (Ag+) detection. …”
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Dendritic cell maturation is induced by p53-armed oncolytic adenovirus via tumor-derived exosomes enhancing systemic antitumor immunity
Published 2024-11-01“…In the present study, the aim was to elucidate the mechanisms of DC activation by OBP-702, focusing particularly on tumor-derived exosomes. Exosomes (Exo53, Exo301, or Exo702) were isolated from conditioned media of human or murine pancreatic cancer cell lines (Panc-1, MiaPaCa-2, and PAN02) after treatment with Ad-p53, OBP-301, or OBP-702. …”
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Brine-Induced Tribocorrosion Accelerates Wear on Stainless Steel: Implications for Mars Exploration
Published 2021-01-01“…Our results do not compromise the nominal ExoMars mission but have implications for future long-term surface operations in support of future human exploration or extended robotic missions on Mars.…”
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RETRACTED ARTICLE: Bone mesenchymal stem cell-derived exosomal microRNA-7-5p inhibits progression of acute myeloid leukemia by targeting OSBPL11
Published 2022-01-01“…Exo-miR-7-5p derived from BMSCs exhibited tumor homing effects in vitro and in vivo, and inhibited AML development. …”
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Comparison of Immunosuppressive and Angiogenic Properties of Human Amnion-Derived Mesenchymal Stem Cells between 2D and 3D Culture Systems
Published 2019-01-01“…The regenerative potential of both 3D culture-derived conditioned medium (3D CM) and their exosomes (EXO) was assessed against 2D culture products. In particular, tubulogenesis assays revealed increased capillary maturation in the presence of 3D CM compared with both 2D CM and 2D EXO. …”
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First report of MDR virulent Pseudomonas aeruginosa in apparently healthy Japanese quail (Coturnix japonica) in Bangladesh.
Published 2025-01-01“…Virulence gene analysis revealed the consistent presence of exoA and rhlR in all isolates, while exoS, exoY, rhlI, and rhlAB showed variable distribution. …”
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Promising Therapeutic Functions of Bone Marrow Mesenchymal Stem Cells Derived-Exosome in Asthma
Published 2022-01-01“…However, BMMSC-Exo still lacked more clinical trials for evaluating the effects on asthma, and the technology of extraction and purification still needs to be improved for wide use. …”
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Exosomal miR-21-5p from glioma associated mesenchymal stem cells promotes the progression and glycolysis of glioblastoma via PDHA1
Published 2025-01-01“…This study aims to explore the relationship between GaMSC derived exosomes (GAMSC-EXO) and PDHA1, as well as the effects and mechanisms on GBM glucose metabolism. …”
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Targeted inhibition of ferroptosis in bone marrow mesenchymal stem cells by engineered exosomes alleviates bone loss in smoking-related osteoporosis
Published 2025-04-01“…Using genetic engineering techniques, we introduced α-1,3-fucosyltransferase 6 (Fut6), a key protein involved in prostate cancer bone metastasis, and identified exosomes expressing Fut6 (F6-exo) with bone-targeting capabilities. Additionally, we modified these exosomes with a bone-targeting peptide, (AspSerSer)6, to synthesize F6-(DSS)6-exo. …”
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Leishmania mexicana: Novel Insights of Immune Modulation through Amastigote Exosomes
Published 2020-01-01“…We here show that exosomes of L. mexicana amastigotes (aExo) contain the virulence proteins gp63 and PP2C. …”
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An Investigation of the Enolization and Isomeric Products Distribution in the Water Promoted Aldol Reaction of Tropinone and Granatanone
Published 2016-01-01“…The exo,anti/exo,syn-diastereoselectivity of water promoted direct aldol reactions of tropinone and granatanone (pseudopelletierine) is strongly dependent on the amount of water added and aromatic aldehyde used. …”
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Myofibroblast-derived exosomes enhance macrophages to myofibroblasts transition and kidney fibrosis
Published 2024-12-01“…Mice treatment with myofibroblast-derived exosomes (Myo-Exo) exhibited severe fibrotic lesion and more abundant MMT cells in kidneys with folic acid (FA) injury, which was negated by TANK-banding kinase-1 inhibitor. …”
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Changes in Circulating BDNF in relation to Sex, Diet, and Exercise: A 12-Week Randomized Controlled Study in Overweight and Obese Participants
Published 2019-01-01“…Body weight was reduced in all intervention groups (p<0.006). Exercise (EXO group) induced a 22% reduction in circulating BDNF in men (p=0.037) and women (p=0.080). …”
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Exosomal miR-141-3p from PDLSCs Alleviates High Glucose-Induced Senescence of PDLSCs by Activating the KEAP1-NRF2 Signaling Pathway
Published 2023-01-01“…PDLSC-Exos were cocultured with senescent PDLSCs to further explore the role of PDLSC-Exos in cellular senescence and determine the differences in cellular oxidative stress levels after PDLSC-Exo treatment. …”
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Comparative transcriptomic and phenotypic analysis of monoclonal and polyclonal Populus deltoides genotypes
Published 2025-01-01“…RNA sequencing revealed upregulation of key genes such as exocyst subunit exo70 family protein H7 (EXO70H7), NDH-dependent cyclic electron flow 5 (NDF5), and expansin-like A3 (EXLA3). …”
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De l’os, de l’ennemi et du divin. Réflexions sur quelques pratiques funéraires tupi-guarani
Published 2003-06-01“…If the greatest contrast is that between vengeful exo-cannibalism and the cult of bones, there is also, within the former, a culturally determined gradation in the treatment of the bones during consumption of the corpse.…”
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Estereotipos sobre España en el paisaje lingüístico de París
Published 2018-03-01“…This perspective will enable us to analyze in a non-Spanish speaking country, therefore the exo-group, the articulation of national identities and other groups, one of the issues tackled in the present monograph.…”
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Cuando la alimentación se convierte en gastronomía. Procesos de activación patrimonial de tradiciones alimentarias
Published 2024-06-01“…El estudio de distintos referentes empíricos permite identificar tres modelos ideales a través de los cuales la alimentación es elevada a la categoría de patrimonio cultural: exo-patrimonialización, endo-patrimonialización y patrimonialización negociada. …”
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