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Clinical features and progression of Parkinson's disease with LRRK2 variants: A prospective study
Published 2025-01-01“…Results The LRRK2‐G2385R variant showed slower progression in tremor symptoms and excessive daytime sleepiness compared with IPD. In contrast, symptoms associated with LRRK2‐R1628P and LRRK2‐A419V were more similar to those of IPD. …”
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Microwave coprocessing of modafinil with Gelucire®: Thermal and compression characteristics
Published 2025-01-01“… Introduction: Modafinil, a wakefulness-promoting agent, is primarily used to treat excessive daytime sleepiness associated with narcolepsy and fatigue. …”
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Impact of Preoperative Daytime Sleepiness and Insomnia on Therapy Adherence and Neurostimulation Amplitude in Unilateral Hypoglossal Nerve Stimulation
Published 2025-02-01“…We provide evidence that pre-operative excessive daytime sleepiness may seriously impair adherence to HGNS therapy.Keywords: obstructive sleep apnea, hypoglossal nerve stimulation, adherence, sleepiness, insomnia, positive airway pressure therapy…”
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Psychosocial, physical, cognitive and quality of life aspects in primary restless legs syndrome
Published 2019-09-01“…The syndrome is accompanied by nocturnal sleep disturbances and excessive daytime sleepiness. There is a number of studies on relationship between RLS and cognitive decline, however, their results are controversial. …”
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Intravenous Immunoglobulin Therapy Administered Early after Narcolepsy Type 1 Onset in Three Patients Evaluated by Clinical and Polysomnographic Follow-Up
Published 2018-01-01“…Narcolepsy type 1 is a rare disabling sleep disorder mainly characterized by excessive daytime sleepiness and cataplexy, an emotion-triggered sudden loss of muscle tone. …”
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Exploring SLEEPINESS through home monitoring with ultra-long-term subcutaneous EEG and ecological momentary assessment in sleepy treatment naïve obstructive sleep apnea patients st...
Published 2025-01-01“…IntroductionExcessive daytime sleepiness (EDS) is a key symptom for patients with obstructive sleep apnea (OSA). …”
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Differences in patients derived from otolaryngology and other specialties with sleep apnea
Published 2019-10-01“…Abstract Background Snoring is a main concern in patients who consult an otolaryngologist (ENT physicians) and patients who have cardiovascular comorbidities or excessive daytime sleepiness who usually consult with other specialists. …”
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Lower Urinary Tract and Gastrointestinal Dysfunction Are Common in Early Parkinson’s Disease
Published 2020-01-01“…Patients with fatigue (beta = 4.28, p<0.001), probable rapid eye movement sleep behavior disorder (beta = 2.71, p<0.001), excessive daytime sleepiness (beta = 1.88,p=0.039), impulsivity and compulsivity (beta = 2.42, p<0.001), and increasing age (beta = 1.05, p<0.001) were more likely to have high dysautonomic scores. …”
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