Association between long-term ambient air pollution exposure and the incidence of breast cancer: A meta-analysis based on updated evidence by Ruohan Wang, Peihan Wang, Yongkang Zhou, Yinan Wang, Chengdong Xu, Zhenbo Wang, Wei Wang

“…Exposure to both NO2 and PM2.5 was associated with breast cancer incidence in Europe, whereas in North America, only NO2 exposure showed a significant association. …”
Get full text

The Late Orchid Catches the Bee: Frost Damage and Pollination Success in the Face of Global Warming in a European Terrestrial Orchid by Florian P. Schiestl, Beat A. Wartmann, Ruth Bänziger, Brigitte Györög‐Kobi, Klaus Hess, Jürg Luder, Edith Merz, Beat Peter, Max Reutlinger, Tobias Richter, Heinz Senn, Thomas Ulrich, Beate Waldeck, Claudia Wartmann, Roland Wüest, Walter Wüest, Quint Rusman

“…Our study shows that the orchid, despite being limited to warm habitats in central Europe, suffers under global warming by increased frost damage caused by earlier flowering. …”
Get full text

What all physicians should know about women’s health: a Delphi study by Susanna Price, Eva Gerdts, Julien Mazières, Alexandra Kautzky-Willer, Fedde Scheele, Chiara Benedetto, Kerry Wilbur, Gertraud Stadler, Marieke Wermer, Jeanine Roeters van Lennep, Merel H de Heer-Koster, Vesna Bjegović-Mikanović, Indre Banaitytė-Baleišienė, Mary Perdiou, Alyson McGregor, Connie Newman, Simona Stankevičiūtė, Iris E Sommer, Florence Thibaut, Karine van 't Land

“…Participants were recruited from Europe and Northern America through the experts’ networks and snowball sampling. …”
Get full text

Propolis mouthwashes efficacy in managing gingivitis and periodontitis: a systematic review of the latest findings by Muhammed Al-Huda Ballouk, Mohamed Altinawi, Abeer Al-Kafri, Talar S. Zeitounlouian, Piotr S. Fudalej

“…Data sources Research findings from 6 different databases: China National Knowledge Infrastructure (CNKI), PubMed®, Europe PMC, Cochrane Central Register of Controlled Trials (CENTRAL), BioMed Central, and Google Scholar, were retrieved and examined in addition to a manual search in the references lists. …”
Get full text

COVID-19 and children with congenital anomalies: a European survey of parents’ experiences of healthcare services by Ingeborg Barisic, Carlos Matias Dias, Amanda Neville, Anna Pierini, Anke Rissmann, Joan K Morris, Judith Rankin, Ester Garne, Anna Latos-Bielenska, Elena Marcus, Anna Jamry-Dziurla, Ljubica Odak, Clara Cavero- Carbonell, Elly Den Hond, Lucas Genard, Ana João Santos, L Renée Lutke, Christina Neergaard Pedersen, Annika Niemann, Lucía Páramo-Rodríguez

“…Objective To survey parents and carers of children with a congenital anomaly across Europe about their experiences of healthcare services and support during the COVID-19 pandemic.Design Cross-sectional study.Setting Online survey in 10 European countries, open from 8 March 2021 to 14 July 2021.Population 1070 parents and carers of children aged 0–10 years with a cleft lip, spina bifida, congenital heart defect (CHD) requiring surgery and/or Down syndrome.Main outcome measures Parental views about: the provision of care for their child (cancellation/postponement of appointments, virtual appointments, access to medication), the impact of disruptions to healthcare on their child’s health and well-being, and satisfaction with support from medical sources, organisations and close relationships.Results Disruptions to healthcare appointments were significantly higher (p<0.001) in the UK and Poland, with approximately two-thirds of participants reporting ‘cancelled or postponed’ tests (67/101; 256/389) and procedures compared with approximately 20% in Germany (13/74) and Belgium/Netherlands (11/55). …”
Get full text

A customizable multiplex protein microarray for antibody testing and its application for tick-borne and other infectious diseases by Hari Krishnan Krishnamurthy, Vasanth Jayaraman, Karthik Krishna, Tianhao Wang, Kang Bei, Chithra Changalath, Shiny Matilda, Alex J. Rai, Renata Welc-Falęciak, Agnieszka Pawełczyk, Lucas S. Blanton, Aleš Chrdle, Andrea Fořtová, Daniel Růžek, Gheyath K. Nasrallah, Laith J. Abu-Raddadi, Duaa W. Al-Sadeq, Marah Abed Alhakim Abdallah, Daniele Lilleri, Chiara Fornara, Piera D’Angelo, Milena Furione, Maria Söderlund-Venermo, Klaus Hedman, Dimosthenis Chochlakis, Eirini Makridaki, Artemis Ntoula, Anna Psaroulaki, Angélica Escárcega-Ávila, John J. Rajasekaran

“…Ticks harbor and transmit several infections with Lyme disease being the most common tickborne infection in the US and Europe. Lack of awareness about tick populations, specific diagnostic tests, and overlapping signs and symptoms of tick-borne infections can often lead to misdiagnosis affecting treatment and the prevalence data reported especially for non-Lyme tick-borne infections. …”
Get full text

Development of a latency model for HIV-1 subtype C and the impact of long terminal repeat element genetic variation on latency reversal by Shreyal Maikoo, Robert-Jan Palstra, Krista L. Dong, Tokameh Mahmoudi, Thumbi Ndung'u, Paradise Madlala

“…However, HIV-1 subtype B (HIV-1B), prevalent in Europe and North America, has been the focus of most cure research and testing despite making up only 12 % of HIV-1 infections globally. …”
Get full text

The Use of Biopsy and “No-Biopsy” Approach for Diagnosing Paediatric Coeliac Disease in the Central European Region by Petra Riznik, Márta Balogh, Piroska Bódi, Luigina De Leo, Jasmina Dolinsek, Ildikó Guthy, Judit Gyimesi, Ágnes Horváth, Ildikó Kis, Martina Klemenak, Berthold Koletzko, Sibylle Koletzko, Ilma Rita Korponay-Szabó, Tomaz Krencnik, Tarcisio Not, Goran Palcevski, Éva Pollák, Daniele Sblattero, István Tokodi, Matej Vogrincic, Katharina Julia Werkstetter, Jernej Dolinsek

“…The aim of our study was to evaluate how frequently paediatric gastroenterologists in Central Europe used the “no-biopsy” approach and how often the duodenal biopsy could have been omitted. …”
Get full text

Evidence-based clinical standard for the diagnosis and treatment of candidemia in critically ill patients in the intensive care unit by Jorge Alberto Cortés, Martha Carolina Valderrama-Rios, Paula M. Peçanha-Pietrobom, Moacyr Silva Júnior, Cándida Diaz-Brochero, Rafael Ricardo Robles-Torres, Carmelo José Espinosa-Almanza, Laura Cristina Nocua-Báez, Marcio Nucci, Carlos Arturo Álvarez-Moreno, Flavio Queiroz-Telles, Ricardo Rabagliati, Rita Rojas-Fermín, Jorge L. Finquelievich, Fernando Riera, Patricia Cornejo-Juárez, Dora E. Corzo-León, Luis E. Cuéllar, Jeannete Zurita, Augusto Raúl Hernández, Arnaldo Lopes Colombo

“…Studies carried out in Latin America reveal a higher incidence of candidemia and higher mortality rates when compared to North America or Europe. This highlights the need to develop guidelines for correctly diagnosing and treating candidemia in critically ill patients in the ICU. …”
Get full text

Efficacy and safety of gut microbiome-targeted treatment in patients with depression: a systematic review and meta-analysis by Bo Pan, Yiming Pan, Yu-Song Huang, Meng Yi, Yuwei Hu, Xiaoyu Lian, Hui-Zhong Shi, Mingwei Wang, Guifen Xiang, Wen-Yi Yang, Zhong Liu, Fangfang Xia

“…Subgroup analyses by geography showed that effectiveness was demonstrated in Asia (SMD −0.46, 95% CI [−0.56, −0.36], I 2  = 36%), while no evidence of effectiveness was found in Europe (SMD −0.07, 95% CI [−0.19, 0.05], I 2  = 55%), America (SMD −0.33, 95% CI [−0.67, 0.02], I 2  = 60%), and Oceania (SMD 0.00, 95% CI [−0.18, 0.18], I 2  = 0%). …”
Get full text

Climats et origines des grands singes et des hommes by Brigitte Senut

“…Nous partageons avec les grands singes plus de 20 millions d'années de notre histoire qui s'est déroulée sur les trois continents de l’Ancien Monde (Afrique, Asie et Europe). Les données de la biologie du vivant et de la paléontologie montrent que les grands singes africains et les hommes sont de proches parents. …”
Get full text

NEK4: prediction of available drug targets and common genetic linkages in bipolar disorder and major depressive disorder by Bin Gong, Chenxu Xiao, Yu Feng, Yu Feng, Jing Shen

“…For BD, the study utilized a comprehensive meta-analysis comprising 57 BD cohorts from Europe, North America, and Australia, including 41,917 BD cases and 371,549 controls of European ancestry. …”
Get full text

Relevance of the synergy of surveillance and populational networks in understanding the Usutu virus outbreak within common blackbirds (Turdus merula) in Metropolitan France, 2018 by Bouchez-Zacria, Malika, Calenge, Clément, Villers, Alexandre, Lecollinet, Sylvie, Gonzalez, Gaelle, Quintard, Benoit, Leclerc, Antoine, Baurier, Florence, Paty, Marie-Claire, Faure, Éva, Eraud, Cyril, Decors, Anouk

“…Usutu virus (USUV) was first isolated in Africa in 1959 and has since spread to and through Europe with a typical enzootic mosquito-bird cycle. …”
Get full text

Physicochemical Properties and Bioreactivity of Sub‐10 μm Geogenic Particles: Comparison of Volcanic Ash and Desert Dust by Ines Tomašek, Julia Eychenne, David E. Damby, Adrian J. Hornby, Manolis N. Romanias, Severine Moune, Gaëlle Uzu, Federica Schiavi, Maeva Dole, Emmanuel Gardès, Mickael Laumonier, Clara Gorce, Régine Minet‐Quinard, Julie Durif, Corinne Belville, Ousmane Traoré, Loïc Blanchon, Vincent Sapin

Get full text

Pharmacokinetic Analysis of an Isoniazid Suspension Among Spanish Children Under 6 Years of Age by Antoni Noguera-Julian, Emma Wilhelmi, Maria Cussó, Rob Aarnoutse, Angela Colbers, Loreto Martorell, Maria Goretti López-Ramos, Joan Vinent, Rosa Farré, Dolors Soy, Sílvia Simó-Nebot, Clàudia Fortuny

“…Currently, there are no INH suspensions available in Europe. <b>Methods</b>: We aimed to characterize the pharmacokinetics of a licensed INH suspension (10 mg/mL, Pharmascience Inc., Montreal, QC, Canada) in children receiving INH daily at 10 mg/kg in a single-center, open-label, non-randomized, phase IIa clinical trial (EudraCT Number: 2016-002000-31) in Barcelona (Spain). …”
Get full text

Evidence Gaps and Lessons in the Early Detection of Atrial Fibrillation: A Prospective Study in a Primary Care Setting (PREFATE Study) by Josep L. Clua-Espuny, Alba Hernández-Pinilla, Delicia Gentille-Lorente, Eulàlia Muria-Subirats, Teresa Forcadell-Arenas, Cinta de Diego-Cabanes, Domingo Ribas-Seguí, Anna Diaz-Vilarasau, Cristina Molins-Rojas, Meritxell Palleja-Millan, Eva M. Satué-Gracia, Francisco Martín-Luján

“…<b>Background/Objectives:</b> In Europe, the prevalence of AF is expected to increase 2.5-fold over the next 50 years with a lifetime risk of 1 in 3–5 individuals after the age of 55 years and a 34% rise in AF-related strokes. …”
Get full text

Potential of long-term satellite observations and reanalysis products for characterising soil drying: trends and drought events by M. Hirschi, P. Stradiotti, B. Crezee, B. Crezee, W. Dorigo, S. I. Seneviratne

“…Geographically, drying is localised to parts of Europe and the Mediterranean; the Black Sea–Caspian Sea and Central Asian region; Siberia; parts of the western USA and the Canadian Prairies; and larger parts of South America, parts of southern and northern Africa, and parts of northwestern Australia.…”
Get full text

Prostate cancer incidence and mortality linked to metalworking fluid exposure: a systematic review and meta-analysis by Zahra Moradpour, Amin Barik, Goljamal Jorjani, Mohammad Reza Taherian, Sepideh Tousizadeh, Sepideh Tousizadeh, Aram Halimi, Aram Halimi, Yaser Soleimani, Mobina Karimian, Tina Khavari, Fateme Azizi Kalankari, Fatemeh Asadipour, Mojtaba Azari, Niloofar Yousefzadeh Shakouri, Saeideh Karamian, Nasser Bahari, Alireza Mosavi Jarrahi

“…BackgroundProstate cancer is the second most diagnosed cancer in men globally, with high prevalence in North America, Europe, and Australia. Occupational exposures, including metalworking fluids (MWFs), have emerged as a potential risk factor for prostate cancer, yet comprehensive studies on this association are limited.ObjectiveThis study aims to systematically review and conduct a meta-analysis to examine the incidence and mortality of prostate cancer linked to MWF exposure.MethodsA systematic review and meta-analysis were conducted following the PRISMA guidelines. …”
Get full text

A global Corynebacterium diphtheriae genomic framework sheds light on current diphtheria reemergence by Hennart, Mélanie, Crestani, Chiara, Bridel, Sébastien, Armatys, Nathalie, Brémont, Sylvie, Carmi-Leroy, Annick, Landier, Annie, Passet, Virginie, Fonteneau, Laure, Vaux, Sophie, Toubiana, Julie, Badell, Edgar, Brisse, Sylvain

“…Background: Diphtheria, caused by Corynebacterium diphtheriae, reemerges in Europe since 2022. Genomic sequencing can inform on transmission routes and genotypes of concern, but currently, no standard approach exists to detect clinically important genomic features and to interpret emergence in the global C. diphtheriae population framework. …”
Get full text

The use of antimicrobials in Italian buffalo farms by Gabriele Di Vuolo, Federico Scali, Claudia Romeo, Valentina Lorenzi, Chiara D. Ambra, Maria Serrapica, Giovanna Cappelli, Francesca Fusi, Esterina De Carlo, Giovanni Loris Alborali, Luigi Bertocchi, Domenico Vecchio

“… Antimicrobial resistance (AMR) is a major global health emergency; 25,000 people die each year in Europe from infections sustained by resistant bacteria. …”
Get full text