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141
A Short Report on the Markov Property of DNA Sequences on 200-bp Genomic Units of ENCODE/Broad ChromHMM Annotations: A Computational Perspective
Published 2018-09-01“…The non-coding DNA in eukaryotic genomes encodes a language which programs chromatin accessibility, transcription factor binding, and various other activities. …”
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142
The Bacterial Type III Secretion System as a Broadly Applied Protein Delivery Tool in Biological Sciences
Published 2025-01-01“…The type III secretion system (T3SS) is a nano-machine that allows Gram-negative bacteria to alter eukaryotic host biology by directly delivering effector proteins from the bacterial cytoplasm. …”
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143
The Transcribed-Ultraconserved Regions: A Novel Class of Long Noncoding RNAs Involved in Cancer Susceptibility
Published 2011-01-01“…During recent years, novel approaches and new technologies have revealed a startling level of complexity of higher eukaryotes' transcriptome. A large proportion of the transcriptional output is represented by protein noncoding RNAs (ncRNAs) that arise from the “dark matter” of the genome. …”
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144
Structures and mechanisms of the RNA m<sup>6</sup>A writer
Published 2024-09-01“…N<sup>6</sup>-methyladenosine (m<sup>6</sup>A) is the most prevalent epigenetic modification found in eukaryotic mRNAs and plays a crucial role in regulating gene expression by influencing numerous aspects of mRNA metabolism. …”
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145
IQGAP Family Members in Yeast, Dictyostelium, and Mammalian Cells
Published 2012-01-01“…IQGAPs are found in eukaryotic cells from yeast to human, and localize to actin-containing structures such as lamellipodia, membrane ruffles, cell-cell adhesions, phagocytic cups, and the actomyosin ring formed during cytokinesis. …”
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146
The S-Layer Glycome—Adding to the Sugar Coat of Bacteria
Published 2011-01-01“…Typically, bacterial S-layer glycans are O-glycosidically linked to serine, threonine, or tyrosine residues, and they rely on a much wider variety of constituents, glycosidic linkage types, and structures than their eukaryotic counterparts. As the S-layer glycome of several bacteria is unravelling, a picture of how S-layer glycoproteins are biosynthesized is evolving. …”
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147
Coleopteran Antimicrobial Peptides: Prospects for Clinical Applications
Published 2012-01-01“…Although coleopterans comprise the largest and most diverse order of eukaryotes and occupy an earlier branch than Drosophila in the holometabolous lineage of insects, their immune system has not been studied extensively. …”
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148
Discovery of Evolutionary Loss of the Ubiquitin-like Autophagy-Related ATG12 System in a Lineage of Apicomplexa
Published 2025-01-01“…The autophagy-related ubiquitin-like conjugation systems, the ATG8 and ATG12 systems, are universally conserved in eukaryotes. However, the covalent bond in the ATG12 system has recently been shown to be evolutionarily lost in Apicomplexa. …”
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149
Characterization of extracellular vesicles by capillary zone electrophoresis: A novel concept for characterization of a next-generation drug delivery platform
Published 2024-12-01“…Extracellular vesicles (EVs) are a part of a cell-to-cell communication system of prokaryotic and eukaryotic organisms. Their ability to penetrate biological barriers and to transfer molecules between cells shows their potential as a novel class of drug delivery platform. …”
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150
Overexpression of a Vesicle Trafficking Gene, OsRab7, Enhances Salt Tolerance in Rice
Published 2014-01-01“…Rab7 is a small GTP-binding protein that is distributed widely among eukaryotes. Endocytic trafficking mediated by Rab7 plays an important role in animal and yeast cells, but the current understanding of Rab7 in plants is still very limited. …”
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151
Distribution of the four type VI secretion systems in Pseudomonas aeruginosa and classification of their core and accessory effectors
Published 2025-01-01“…Abstract Bacterial type VI secretion systems (T6SSs) are puncturing molecular machines that transport effector proteins to kill microbes, manipulate eukaryotic cells, or facilitate nutrient uptake. How and why T6SS machines and effectors differ within a species is not fully understood. …”
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152
Cytological and biochemical markers of autophagy in wheat suspension culture cells under abiotic stress
Published 2020-12-01“…Autophagy is a highly conserved process of intracellular degradation of damaged, oxidized or excess macromolecules and organelles in eukaryotic cells. Under optimal conditions, the baseline level of autophagy is low. …”
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153
Functions and applications of RNA interference and small regulatory RNAs
Published 2024-11-01“…Small regulatory RNAs play a variety of crucial roles in eukaryotes, influencing gene regulation, developmental timing, antiviral defense, and genome integrity via a process termed RNA interference (RNAi). …”
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154
Autophagy: More Than a Nonselective Pathway
Published 2012-01-01“…Autophagy is a catabolic pathway conserved among eukaryotes that allows cells to rapidly eliminate large unwanted structures such as aberrant protein aggregates, superfluous or damaged organelles, and invading pathogens. …”
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155
DNA Polymerase e - More Than a Polymerase
Published 2003-01-01“…Together with DNA polymerases a and d, this enzyme replicates the nuclear DNA in the eukaryotic cell. During this process, DNA polymerase a lays down RNA-DNA primers that are utilized by DNA polymerases d and e for the bulk DNA synthesis. …”
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156
Artificial cells with all-aqueous droplet-in-droplet structures for spatially separated transcription and translation
Published 2025-01-01“…Here, we develop artificial cells with all-aqueous droplet-in-droplet structures that separate transcription and translation processes like the nucleus and cytosol in eukaryotic cells. This architecture uses protein-based inner droplets and aqueous two-phase outer compartments, stabilized by colloidal emulsifiers. …”
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157
The Role of Autophagy in Erectile Dysfunction
Published 2025-01-01“…Autophagy is a conservative lysosome-dependent material catabolic pathway, and exists in all eukaryotic cells. Autophagy controls cell quality and survival by eliminating intracellular dysfunction substances, and plays an important role in various pathophysiology processes. …”
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158
A hammerhead ribozyme selects mechanically stable conformations for catalysis against viral RNA
Published 2025-02-01“…Abstract Ribozymes, widely found in prokaryotes and eukaryotes, target nucleic acids and can be engineered as biotechnical tools or for gene regulation or immune therapy. …”
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159
Biosynthesis and Role of N-Linked Glycosylation in Cell Surface Structures of Archaea with a Focus on Flagella and S Layers
Published 2010-01-01“…The N-linked glycosylation system is not essential for any of M. voltae, M. maripaludis, or H. volcanii, as demonstrated by the successful isolation of mutants carrying deletions in the oligosaccharyltransferase gene aglB (a homologue of the eukaryotic Stt3 subunit of the oligosaccharyltransferase complex). …”
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160
Communication between DNA polymerases and Replication Protein A within the archaeal replisome
Published 2024-12-01“…This study provides a molecular understanding of the WH-mediated regulatory activity in central replication factors such as RPA, which regulate genome maintenance in Archaea and Eukaryotes.…”
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