Early childhood constraint therapy for sensory/motor impairment in cerebral palsy: a randomised clinical trial protocol by Garey Noritz, Olena Chorna, Jill Heathcock, Alexandra Key, Helen Carey, Ellyn Hamm, Mary Ann Nelin, Micah Murray, Amy Needham, James C Slaughter, Nathalie L Maitre

“…The research material collected will be in the form of data from high-density array event-related potential scan, standardised assessment scores and motion analysis scores.Ethics and dissemination The study protocol was approved by the Institutional Review Board. …”
Get full text

Protocol for a meta-review of interventions to prevent and manage ICU delirium by Andrew Booth, Maria Pufulete, Ben Gibbison, Burak Kundakci, Katherine Louise Jones

“…We will involve our Patient and Public Involvement group of people who experienced ICU delirium to develop and comment on such aspects as the research question, methodology and which outcomes are most important.Ethics and dissemination No ethical approval is required for this study. …”
Get full text

Developing a priority global research agenda for antimicrobial resistance in the human health sector: protocol for a scoping review by Alessandro Cassini, Raph L Hamers, Koe Stella Asadinia, Silvia Bertagnolio

“…A qualitative content analysis is out of the scope of this protocol.Ethics and dissemination The scoping review process will only involve identification, selection and analysis of documents available for use in the public domain, and will not include any personal information on individuals, therefore ethical approval is not required. …”
Get full text

Estimating the Effectiveness of Pfizer and Sinopharm Vaccines and their Relationship to Occupation, Residence, Smoking, and Body Mass Index During Pregnancy Smoking by Shahad Th. Jameel, Asmaa Haseeb Hwaid, Abdulrazak SH. Hasan

“…Written consent was obtained by the Research Ethics Committee in the Diyala Health Department(DHD/No-39072/Date-31/8/2022).The researchers collected the data using a specific questionnaire they created after conducting a brief interview with the participants. …”
Get full text

Optimising transitions of care for acute kidney injury survivors: protocol for a mixed-methods study of nephrologist and primary care provider recommendations by Rozalina Grubina McCoy, Kianoush B Kashani, Joan M Griffin, Heather Personett May, Abby K Krauter, Dawn M Finnie, Erin F Barreto

“…Both deductive analysis and inductive analysis will occur to identify and compare themes.Ethics and dissemination This study has been reviewed and deemed exempt by the Institutional Review Board at Mayo Clinic (IRB 20–0 08 793). …”
Get full text

Charting current evidence on the health and non-health benefits and equity impacts of pandemic/epidemic individual-level economic relief programmes: a scoping review protocol by Beate Sander, Ashley Farrell, Gebremedhin Beedemariam Gebretekle, Adeteju Ogunbameru, Adrianna Perryman

“…Our review findings will provide in-depth knowledge on whether and how benefits associated with pandemic/epidemic individual-level economic relief programmes differ across social determinants of health factors.This information is critical for decision-makers as they seek to understand the role of pandemic/epidemic economic mitigation strategies to mitigate the health impact and reduce inequity gap.Ethics and dissemination Since the scoping review methodology aims to synthesise evidence from literature, this review does not require ethical approval. …”
Get full text

Glimepiride monotherapy versus combination of glimepiride and linagliptin therapy in patients with HNF1A-diabetes: a protocol for a randomised, double-blinded, placebo-controlled t... by Torben Hansen, Tina Vilsbøll, Filip Krag Knop, Alexander Sidelmann Christensen, Heidi Storgaard, Sofie Hædersdal

“…The primary end point is the absolute difference in the mean amplitude of glycaemic excursions between the two treatments (glimepiride+linagliptin vs glimepiride+placebo) at the end of each treatment period.Ethics and dissemination The study protocol is approved by the Danish Medicines Agency, The Scientific-Ethical Committee of the Capital Region of Denmark (H-17014518) and the Danish Data Protection Agency. …”
Get full text

Increasing the level of coordination abilities of young taekwondo athletes aged 13-14 under martial law by Elizaveta Lyuchkova, Olena Nesen, Pavol Bartik, Jerzy Skrobecki

“…This study was conducted by the Declaration of Helsinki and was approved by the Ethics Committee of University. All participants were aware during the informed consent process that the results of this study may be published. …”
Get full text

Pharmacological interventions for hidradenitis suppurativa: a protocol for systematic review and network meta-analysis of randomised trials and non-randomised studies by Phichayut Phinyo, Surapon Nochaiwong, Naritthorn Aroonsakul, Lalita Lumkul, Nutcha Jarupanich, Jacek Szepietowski, Mati Chuamanochan

“…Evidence-based synthesis will be based on the magnitudes of effect size, evidence certainty and the surface under the cumulative ranking curve values.Ethics and dissemination Ethical approval is not required because this study is based on existing published data. …”
Get full text

Health system governance for injury care in low- and middle-income countries: a survey of policymakers and policy implementors by Alice Sitch, Justine Davies, Kathryn Chu, Stephen Tabiri, Junaid Razzak, Lucia D’Ambruoso, Alemayehu Amberbir, Abebe Bekele, Agnieszka Ignatowicz, Mohammed Bukari, Derbew Fikadu Berhe, Barnabas Alayande, Pascal Nzasabimana, Jean Claude Byiringiro, Huba Atiq, Komal Abdul Rahim, Jane Acquaye, Anita Eseenam Agbeko, Napoleon Bellua Sam, Leila Ghalichi, Denys Ndangurura, Irene Bagahirwa, Dominic Konadu-Yeboah, Frederick Sarfo-Antwi, Lambert Nzungize, Ntombekhaya Tshabalala, Richard Osei, Tamlyn MacQuene, Zaheer Babar Chand, Zabin Wajidali, Adams Dramani, Ebenezer Kwame Amofa, Eric Twizeyimana, Fazila Sahibjan, Ghislaine Umwali, Mehreen Mustafa, Nadine Mugisha, Tariq Jakhro

“…Input was captured in 10 domains: strategic vision; participation and consensus; rule of law; transparency; responsiveness; equity and inclusion; effectiveness and efficiency; accountability; intelligence and information; and ethics.Result The median injury care governance score across all domains and countries was 29% (IQR 17–43). …”
Get full text

Protocol to study the impact of breast cancer on colonization resistance of mouse microbiota using network node manipulation by Ana Laura Cano-Argüelles, Alejandra Wu-Chuang, Lourdes Mateos-Hernandez, Lianet Abuin-Denis, Apolline Maitre, Janet Avellanet, Arlem García, Dasha Fuentes, Alejandro Cabezas-Cruz

“…We then detail steps for constructing co-occurrence networks based on correlations between microbial abundances.For complete details on the use and execution of this protocol, please refer to Wu-Chuang et al.1 : Publisher’s note: Undertaking any experimental protocol requires adherence to local institutional guidelines for laboratory safety and ethics.…”
Get full text

Adolescents: Contraceptive Knowledge and Use, a Brazilian Study by Divanise S. Correia, Ana C. P. Pontes, Jairo C. Cavalcante, E. Sócrates T. Egito, Eulália M.C. Maia

“…This study was approved by the Human Research Ethics Committee, and Epi InfoTM software was used for data and result evaluation using the mean and chi-square statistical test. …”
Get full text

Protocol for development of an assessment tool for competency of ECG interpretation: expert consensus by the RAND/UCLA appropriateness method and cross-sectional testing using mult... by Shinji Inaba, Toshi A Furukawa, Osamu Yamaguchi, Masatsugu Sakata, Kazumichi Yamamoto, Tomohiro Kaga, Muhammad Wannous

“…A test set of question items for ECG interpretation will be proposed on the basis of the extracted parameters.Ethics and dissemination The protocol of this study was approved by the Institutional Review Board of Ehime University Graduate School of Medicine (IRB number: 2209008). …”
Get full text

Care, conflict, and coexistence: Human–wildlife relations in community forests by Madison Stevens, Shalini Rawat, Terre Satterfield

“…Our findings indicate high prevalence of HWC and associated hardships (mentioned by 71% of survey participants), alongside high expressed ethics of care, tolerance, and responsibility for wild animals (60%). …”
Get full text

Medication following bariatric surgery for type 2 diabetes mellitus (BY-PLUS) study: rationale and design of a randomised controlled study by Alexander Dimitri Miras, Carel le Roux, Alexis Sudlow, Ricardo Vitor Cohen, Hassan Kahal, Dimitri J Pournaras, Jill Townley, Helen Heneghan

“…The primary endpoints are the proportion of patients in each arm with an HbA1c<6.5% (48 mmol/mol) at 1 year and the proportion of patients in each arm achieving the composite endpoint of HbA1c<6.5% (48 mmol/mol), BP<130/80 mm Hg and LDL<2.6 mmol/L at 5 years.Ethics and dissemination The local institutional review board approved this study. …”
Get full text

Measuring anti-transgender stigma in low-income and middle-income countries: a scoping review protocol by Clare Barrington, Jennifer Toller Erausquin, Amanda E Tanner, Tamar Goldenberg, Sulianie Mertus, Mohammed Sheikh Eldin Jibriel

“…A narrative summary of findings will be conducted.Ethics and dissemination As a scoping review (no direct interaction with participants), this study is exempt from human subjects oversight. …”
Get full text

Protozoan Parasites of Rodents and Their Zoonotic Significance in Boyer-Ahmad District, Southwestern Iran by Zeinab Seifollahi, Bahador Sarkari, Mohammad Hossein Motazedian, Qasem Asgari, Mohammad Javad Ranjbar, Samaneh Abdolahi Khabisi

“…Each rodent was anesthetized with ether, according to the ethics of working with animals, and was dissected. …”
Get full text

Protocol for predicting host-microbe interactions and their downstream effect on host cells using MicrobioLink by Lejla Gul, Anna Julia Elias, Tanvi Tambaku, Marton Olbei, Emily Watters, Balazs Bohar, Dezso Modos, Matthew Madgwick, Tamas Korcsmaros

“…The protocol outlines procedures for predicting protein-protein interactions through domain-motif interactions, integrating multi-omic datasets to map downstream effects, performing network analyses to identify key regulatory pathways, and visualizing multi-layered networks for systems-level data interpretation.For complete details on the use and execution of this protocol, please refer to Gul et al.1 and Poletti et al.2 : Publisher’s note: Undertaking any experimental protocol requires adherence to local institutional guidelines for laboratory safety and ethics.…”
Get full text

Effectiveness of interventions on healthcare professionals’ understanding and use of conscience: a systematic review protocol by Alex Clark, Megan Kennedy, Christina Lamb, Edith Pituskin, Ken Kirkwood, Yolanda Babenko-Mould

“…The quality of the aggregate evidence will be assessed using the Grading of Recommendations, Assessment, Development and Evaluations criteria.Ethics and dissemination Ethical approval is not required for this review. …”
Get full text

Current Status and Future Directions of Artificial Intelligence in Post-Traumatic Stress Disorder: A Literature Measurement Analysis by Ruoyu Wan, Ruohong Wan, Qing Xie, Anshu Hu, Wei Xie, Junjie Chen, Yuhan Liu

“…However, there are numerous challenges, and fully realizing AI’s potential will require overcoming hurdles in algorithm design, data integration, and societal ethics. To promote more extensive and in-depth future research, it is crucial to prioritize the development of standardized protocols for AI implementation, foster interdisciplinary collaboration—especially between AI and neuroscience—and address public concerns about AI’s role in healthcare to enhance its acceptance and effectiveness.…”
Get full text