Diagnosis of Columnar Metaplasia of the Esophageal Mucosa in Patients with Complicated Gastroesophageal Reflux Disease by E. D. Fedorov, A. V. Shidii-Zakrua, L. M. Mikhaleva, K. S. Maslenkina, A. A. Lindenberg, D. E. Seleznev, V. O. Kaybysheva, T. A. Partenadze

“…If an irregular type of metaplasized epithelium structure was detected in the process of BING assessment, the areas suspicious for dysplasia were marked, followed by aim forceps biopsy from them. …”
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Luminal epithelial cells integrate variable responses to aging into stereotypical changes that underlie breast cancer susceptibility by Rosalyn W Sayaman, Masaru Miyano, Eric G Carlson, Parijat Senapati, Arrianna Zirbes, Sundus F Shalabi, Michael E Todhunter, Victoria E Seewaldt, Susan L Neuhausen, Martha R Stampfer, Dustin E Schones, Mark A LaBarge

“…Effects from aging in single cells are heterogenous, whereas at the organ- and tissue-levels aging phenotypes tend to appear as stereotypical changes. The mammary epithelium is a bilayer of two major phenotypically and functionally distinct cell lineages: luminal epithelial and myoepithelial cells. …”
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Dry eye syndrome before corneal refractive surgery: the prevalence and pathogenesis-oriented therapy by N.V. Maychuk, I.S. Malyshev, M.R. Obraztsova

“…An eye gel was recommended for the long-lasting overnight hydration of the corneal epithelium and its faster renewal. As a result of the positive response to the treatment, after 6–8 months of therapy it was possible to perform surgical correction in 6 (54.5%) of 11 patients of this group. …”
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Diagnostics and treatment of gastroesophageal reflux disease: clinical guidelines of the Russian gastroenterological association by V. T. Ivashkin, I. V. Mayev, I. . A.s. Trukhmanov, Ye. K. Baranskaya, O. B. Dronova, O. V. Zayratyants, R. G. Sayfutdinov, A. A. Sheptulin, T. L. Lapina, S. S. Pirogov, Yu. A. Kucheryavy, O. A. Storonova, D. N. Andreyev

“…Esophagogastroduodenoscopy (EGDS) gives the chance to define the presence of reflux esophagitis, to estimate severity grade, to reveal development of esophageal epithelium columnar metaplasia. At the refractory course (lack of conclusive clinical and endoscopic remission within 4-8 wks of treatment by standard dose of proton pump inhibitor - PPI), and development of complications (strictures, Barret's esophagus) examination within specialized hospital or gastroenterological clinic is required, including their out­patient departments. …”
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Current AAV-mediated gene therapy in sensorineural hearing loss by Jieyu Qi, Xiaolong Fu, Liyan Zhang, Fangzhi Tan, Nianci Li, Qiuhan Sun, Xiaojie Hu, Zuhong He, Ming Xia, Renjie Chai

“…The pathology of hearing loss in the inner ear is characterized by varying degrees of damage to the cochlear sensory epithelium cells (such as hair cells and supporting cells), stria vascularis (including marginal, intermediate and basal cells) and spiral ganglion neurons. …”
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Outer retina micro-inflammation is driven by T cell responses prior to retinal degeneration in early age-related macular degeneration by Lucas Stürzbecher, Lucas Stürzbecher, Lucas Stürzbecher, Lucas Stürzbecher, Hendrik Bartolomaeus, Hendrik Bartolomaeus, Hendrik Bartolomaeus, Hendrik Bartolomaeus, Theda U. P. Bartolomaeus, Theda U. P. Bartolomaeus, Theda U. P. Bartolomaeus, Theda U. P. Bartolomaeus, Sylvia Bolz, Andjela Sekulic, Marius Ueffing, Marius Ueffing, Simon J. Clark, Simon J. Clark, Simon J. Clark, Nadine Reichhart, Sergio Crespo-Garcia, Nicola Wilck, Nicola Wilck, Nicola Wilck, Nicola Wilck, Olaf Strauß

“…Dysfunction of the retinal pigment epithelium (RPE) is a unifying salient feature of the pathology and a primary end-point damage leading to complications such as geographic atrophy (GA), which represents the most common end-stage of AMD.MethodsHuman and murine ocular tissues were used for histological examinations. …”
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A Chemically Defined Culture for Tooth Reconstitution by Ziwei Zhang, Hong Hu, Zhiheng Xu, Ce Shan, Hanyi Chen, Kun Xie, Kun Wang, Yifu Wang, Qing Zhu, Yike Yin, Haoyang Cai, Yunqiu Zhang, Zhonghan Li

“…Abstract It is known for decades that dental epithelium and mesenchyme can reconstitute and regenerate a functional tooth. …”
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Local factors determining the response to antiangiogenic therapy with first-line drugs in macular neovascularization by V.G. Likhvantseva, S.G. Kapkova, E.B. Tretyak, S.I. Rychkova, A.S. Gevorkyan, T.E. Borisenko

“…</p> <p> <b>Results</b>: improvement of MNV activity markers in the setting of treatment manifested as reduction in area and height of subretinal fluid (k=0.9432, p&lt;0.01, and k=0.58959, p&lt;0.001), reduction in height and area of retinal pigment epithelium (RPE) detachment (k=0.82808, p&lt;0.05; k=0.50221, p&lt;0.05) and reduction in sub-RPE fluid (k=0.84515, p&lt;0.05) were strongly directly correlated with baseline IOP. …”
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Assessment of photoreceptor recovery and visual function utilizing adaptive optics and microperimetry in patients with surgically closed macular holes by Yuanyuan Liu, Xueli Yang, Wei Zhou, Jinguo Yu, Song Chen, Tiangeng He, Caiyun You, Xiangda Meng, Mengyu Liao, Yi Lei, Hua Yan

“…In contrast, type 2 closures exhibited sparse cone distribution and a prevalence of large, high-density cells, possibly indicating glial cell proliferation and exposed retinal pigment epithelium (RPE). MH size, rather than duration or preoperative BCVA, was a key determinant of type 1 closure outcomes. …”
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Impact of comb type on production performance, egg production quality, reproductive performance, and blood biochemical indexes in Tianfu chickens by Yuxin Zhou, Hengyong Xu, Wei Du, Yuxiang Lu, Zhi Hu, Qingqing Deng, Xi Wang, Yiping Liu, Yao Zhang, Yan Wang

“…In roosters, single-comb had higher germ cell counts, thicker seminiferous epithelium, and better semen quality, leading to improved fertilization rates and hatchability. …”
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Pathological findings in acute and chronic copper toxicity in rainbow trout (oncorhynchus mykiss, walbaum 1792) occurred by copper sulfate pentahydrate by Sema Öztürk, Hamdi Avcı

“…In the kidney, there were degeneration and eosinophilic hyalin droblets with variable sized in the cytoplasm of tubular epitheliums. Liver had diffusive degenerations in Group III. …”
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