Non-medical treatment for late age-related macular degeneration by A.K. Drakon, A.G. Kurguzova, V.M. Sheludchenko, N.B. Korchazhkina

“…It was demonstrated that retinal pigment epithelium (RPE) cells derived from human embryonic stem cells or induced pluripotent stem cells express typi cal RPE markers that can phagocytize photoreceptor segments. …”
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Cloned airway basal progenitor cells to repair fibrotic lung through re-epithelialization by Yu Zhao, Yueqing Zhou, Weipan Zhang, Mingzhe Liu, Jun Duan, Xiaopeng Zhang, Qiwang Ma, Yujia Wang, Yuzhen Zhang, Zhongliang Guo, Ting Zhang, Wei Zuo

“…Abstract Irreversible damage of the lung epithelium in idiopathic pulmonary fibrosis (IPF) patients causes high mortality worldwide, with no lung repair approaches available currently. …”
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Melatonin improves endometrial receptivity and embryo implantation via MT2/PI3K/LIF signaling pathway in sows by Xue Qin, Menghao Yang, Yang Yu, Xiaolin Wang, Yi Zheng, Rui Cai, Weijun Pang

“…In cells treated with melatonin, the MT2/PI3K/LIF axis played a role in reducing lipid accumulation in porcine endometrial epithelium cells and improved endometrial receptivity. …”
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The Association of HOTAIR with the Diagnosis and Prognosis of Gastric Cancer and Its Effect on the Proliferation of Gastric Cancer Cells by Zhiying Xu, Hui Chen, Bin Yang, Xiangfeng Liu, Xiaoli Zhou, Hongfang Kong

“…The expression levels of HOTAIR in human GC cell lines and a normal gastric epithelium cell line were also assessed by qRT-PCR. …”
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Tear metabolomics reveals novel potential biomarkers in epithelial herpes simplex keratitis by Jinyu Zhang, Zhenning Wu, Yangqi Zhang, Kaili Wu, Xiaoyi Li, Shiyou Zhou

“…Abstract Background Herpes simplex keratitis (HSK) is a recurrent inflammatory disease of cornea primarily initiated by type I herpes simplex virus infection of corneal epithelium. However, early diagnosis of HSK remains challenging due to the lack of specific biomarkers. …”
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Microbiota governs host chenodeoxycholic acid glucuronidation to ameliorate bile acid disorder induced diarrhea by Zishen Lin, Yue Feng, Jinping Wang, Zhaoyue Men, Xi Ma

“…Results Here, we reveal for the first time that core microbiota derived I3C represses gut epithelium glucuronidation, particularly 3β-glucuronic CDCA production, which reaction is mediated by host UDP glucuronosyltransferase family 1 member A4 (UGT1A4) and necessary of BA disorder induced diarrhea. …”
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An Unusual Case of Ototoxicity with Use of Oral Vancomycin by Umut Gomceli, Srija Vangala, Cosmina Zeana, Paul J. Kelly, Manisha Singh

“…The potential for absorption of oral vancomycin is not well described and is attributed to compromised intestinal epithelium allowing for increased drug absorption. Few studies suggested that oral vancomycin may result in therapeutic or even potentially toxic levels of serum vancomycin in patients with impaired renal function. …”
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Scent of COVID-19: Whole-Genome Sequencing Analysis Reveals the Role of <i>ACE2</i>, <i>IFI44</i>, and <i>NDUFAF4</i> in Long-Lasting Olfactory Dysfunction by Beatrice Spedicati, Alessandro Pecori, Maria Pina Concas, Aurora Santin, Romina Ruberto, Giuseppe Giovanni Nardone, Andrea D’Alessandro, Giancarlo Tirelli, Paolo Boscolo-Rizzo, Giorgia Girotto

“…Considering the physiological role of the proteins encoded by these genes, it can be hypothesized that a reduced expression of <i>ACE2</i> may be associated with a protracted and severe inflammatory response in the olfactory epithelium, thus worsening patients’ smell abilities. …”
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Behavioral Improvement and Regulation of Molecules Related to Neuroplasticity in Ischemic Rat Spinal Cord Treated with PEDF by Chary Marquez Batista, Leonardo Luis Torres Bianqui, Bruno Bonganha Zanon, Mauricio Menezes Aben Athar Ivo, Gabriela Pintar de Oliveira, Jessica Ruivo Maximino, Gerson Chadi

“…Pigment epithelium derived factor (PEDF) exerts trophic actions to motoneurons and modulates nonneuronal restorative events, but its effects on neuroplasticity responses after spinal cord (SC) injury are unknown. …”
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Heat-not-burn technology affects plasma testosterone levels and markers of inflammation, oxidative stress in the testes of rats by Silvia Granata, Camilla Morosini, Maria Chiara Valerii, Ivan Fagiolino, Stefano Sangiorgi, Severino Ghini, Enzo Spisni, Fabio Vivarelli, Lucy C. Fairclough, Moreno Paolini, Donatella Canistro

“…The impairment of some androgenic key enzymes and those related to the activity of seminiferous epithelium, together with the decrease in testosterone levels, suggest an impairment of gonadal function through the alteration of some cellular pathways typically associated with tobacco consumption.…”
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Molecular Responses of Human Retinal Cells to Infection with Dengue Virus by Jillian M. Carr, Liam M. Ashander, Julie K. Calvert, Yuefang Ma, Amanda Aloia, Gustavo G. Bracho, Soon-Phaik Chee, Binoy Appukuttan, Justine R. Smith

“…Changes in endothelial expression of adhesion molecules are consistent with the retinal vasculopathy seen in patients infected with DENV; decreases in epithelial junctional protein expression, paralleling loss of integrity of the epithelium, provide a molecular basis for DENV-associated macular edema. …”
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Nicotine-induced CHRNA5 activation modulates CES1 expression, impacting head and neck squamous cell carcinoma recurrence and metastasis via MEK/ERK pathway by Chen Feng, Wei Mao, Chenyang Yuan, Pin Dong, Yuying Liu

“…Abstract The mucosal epithelium of the head and neck region (including the oral cavity, nasal cavity, pharynx, nasopharynx, and larynx) is the primary site exposed to tobacco smoke, and its presence of nicotinic acetylcholine receptors (nAChRs) has been observed in the mucosal epithelial cells of this area. …”
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Blood Glucose Lowering Efficacy of Strawberry Extracts Rich in Ellagitannins with Different Degree of Polymerization in Rats by Juśkiewicz Jerzy, Jurgonski Adam, Kołodziejczyk Krzysztof, Kosmala Monika, Milala Joanna, Zduńczyk Zenon, Fotschki Bartosz, Żary-Sikorska Ewa

“…The experiment 1 comprised three oral sugar tolerance tests, GTT (with glucose; to examine monosaccharide transport across epithelium), SuTT (with sucrose; to examine the activity of mucosal disaccharidase) and StTT (with starch; to examine the action of salivary alpha-amylase, and then of pancreatic amylase in the small intestine as well as all the aforementioned mechanisms), while in the experiment 2 the healthy and pre-diabetic rats were subjected to 1-h small intestine perfusion with fluids containing glucose or sucrose. …”
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Serum Levels of Epithelial-Derived Cytokines as Interleukin-25 and Thymic Stromal Lymphopoietin after a Single Dose of Mepolizumab in Patients with Severe Non-Allergic Eosinophilic... by Virginija Kalinauskaite-Zukauske, Andrius Januskevicius, Ieva Janulaityte, Skaidrius Miliauskas, Kestutis Malakauskas

“…The bronchial epithelium has continuous contact with environmental agents initiating and maintaining airway type 2 inflammation in asthma. …”
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Epi-Off versus Epi-On Corneal Collagen Cross-Linking in Keratoconus Patients: A Comparative Study through 2-Year Follow-Up by F. Cifariello, M. Minicucci, F. Di Renzo, D. Di Taranto, G. Coclite, S. Zaccaria, S. De Turris, C. Costagliola

“…To evaluate two different techniques of cross-linking: standard epithelium-off (CXL epi-off) versus transepithelial (CXL epi-on) cross-linking in patient with progressive keratoconus. …”
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Levying evidence of the impact of Triphala in the mildly constipated human colon microbiota by Elizabeth Goya-Jorge, Pauline Bondue, Irma Gonza, Samiha Boutaleb, Caroline Douny, Marie-Louise Scippo, Joël Pincemail, Patrice Chiap, Jeoffrey Christyn de Ribaucourt, Fabienne Crahay, Véronique Delcenserie

“…Fermentation metabolites enhanced transepithelial electrical resistance in a human epithelium model and inhibited aryl hydrocarbon receptor (AhR) transcriptional activity. …”
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Gambaran Jumlah Eosinofil Darah Tepi Penderita Asma Bronkial di Bangsal Paru RSUP Dr. M. Djamil Padang by Demas Nico M Manurung, Ellyza Nasrul, Irvan Medison

“…Eosinophil release a variety of mediators such as Major Basic Protein, Eosinophil Cationic Protein, Eosinophil Peroxidase, Leukotriene C4, and Platelet Activating Factor that will damage airway epithelium and cause inflammation. The research was conducted in January 2012 through December 2012 at Medical Records Department of RSUP Dr. …”
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A stretchable human lung‐on‐chip model of alveolar inflammation for evaluating anti‐inflammatory drug response by Clémentine Richter, Lorenz Latta, Daria Harig, Patrick Carius, Janick D. Stucki, Nina Hobi, Andreas Hugi, Paul Schumacher, Tobias Krebs, Alexander Gamrekeli, Felix Stöckle, Klaus Urbschat, Galia Montalvo, Franziska Lautenschläger, Brigitta Loretz, Alberto Hidalgo, Nicole Schneider‐Daum, Claus‐Michael Lehr

“…In all cases, the presence of macrophages appeared to be crucial to mediating inflammatory changes in the alveolar epithelium. LPS induction led to inflammatory changes independently of stretch conditions. …”
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Serum Vitamin A and Inflammatory Markers in Individuals with and without Chronic Obstructive Pulmonary Disease by L. M. O. Caram, R. A. F. Amaral, R. Ferrari, S. E. Tanni, C. R. Correa, S. A. R. Paiva, I. Godoy

“…Vitamin A is essential for the preservation and integrity of the lung epithelium and exerts anti-inflammatory effects. Objective. …”
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A Surgical Cryoprobe for Targeted Transcorneal Freezing and Endothelial Cell Removal by Alina Akhbanbetova, Shinichiro Nakano, Stacy L. Littlechild, Robert D. Young, Madara Zvirgzdina, Nigel J. Fullwood, Ian Weston, Philip Weston, Shigeru Kinoshita, Naoki Okumura, Noriko Koizumi, Andrew J. Quantock

“…Results. The corneal epithelium was destroyed by transcorneal freezing, as expected; however, the epithelial basement membrane remained intact. …”
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