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561
Hyaluronate Acid-Dependent Protection and Enhanced Corneal Wound Healing against Oxidative Damage in Corneal Epithelial Cells
Published 2016-01-01“…After inducing hyperosmolar conditions, the cell morphologies, cell apoptosis, and expression levels of TNF-α and MMP-9 were detected to assess the protective role of HA. Corneal epithelium-injured rat models were established to test the therapeutic effects of 0.3% HA. …”
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562
Influenza B virus infection alters the regenerative potential of murine alveolar type 2 pneumocytes
Published 2025-02-01“…After epithelial damage, AT2 pneumocytes proliferate for both self-renewal and differentiation into type I pneumocytes to repopulate the epithelium. Theoretically, some of the long-term lung sequelae associated with viral infections could be the result of inappropriate AT2 behavior. …”
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563
In Vivo and Impression Cytology Study on the Effect of Compatible Solutes Eye Drops on the Ocular Surface Epithelial Cell Quality in Dry Eye Patients
Published 2015-01-01“…Our results show that in dry eye disease therapy based on osmoprotective eye drops determines a reduction of inflammatory activation of ocular surface, with consequent improvement of the quality of corneal and conjunctival epithelium.…”
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564
Intraductal Papillary Neoplasms of the Bile Duct
Published 2014-01-01“…Cholangioscopy can confirm the histology and assess the extent of the tumor including superficial spreading along the biliary epithelium. However, pathologic diagnosis by preoperative biopsy cannot always reflect the maximum degree of atypia, because IPNBs are often composed of varying degrees of cytoarchitectural atypia. …”
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565
Long-term copper exposure induced pyroptosis and inflammation of rat spleen through intestinal-splenic axis
Published 2025-01-01“…Our results demonstrated that under copper exposure, the structural integrity of the intestinal epithelium was compromised, resulting in a significant downregulation of genes and proteins expression levels related to the intestinal barrier (Zonula occludens-1, Claudin-1 and Occludin). …”
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566
Selective epithelial expression of KRASG12D in the Oncopig pancreas drives ductal proliferation and desmoplasia that is accompanied by an immune response
Published 2025-02-01“…Microscopic examination revealed concentration-dependent proliferation of the ductal epithelium, cellular atypia, metaplasia, and stromal alterations. …”
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567
IMAGING ASPECTS OF NON-CHOLESTEATOMATOUS CHRONIC OTITIS AND INTRACEREBRAL COMPLICATIONS OF CHOLESTEATOMA IN PATIENTS HOSPITALIZED AND TREATED AT “PROF. N. OBLU” HOSPITAL IN IAȘI...
Published 2024-06-01“…Cholesteatoma is a mass of soft tissue within the middle ear, consisting of keratinized squamous epithelium and keratin accumulation, with or without inflammation of the surrounding tissue. …”
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568
Increased Expression of the Pro-Protein Convertase Furin Predicts Decreased Survival in Ovarian Cancer
Published 2007-01-01“…Methods: We assessed their expression by RT-PCR, Real-time PCR, Western blot, and immunohistochemistry using cells derived from normal human ovarian surface epithelium (HOSE) and cancer cell lines as well as ovarian epithelial cancer specimens (45 RT-PCR/Real-time PCR, and 120 archival specimens for Immunohistochemistry). …”
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569
Retroperitoneal Müllerian cyst causing uterine protrusion in a teenage girl
Published 2025-01-01“…Surgical exploration and excision of the tumor were performed, with histological and immunohistochemical analyses confirming the presence of a Müllerian-type epithelium. Post-surgery, the protruding uterus improved, and the patient demonstrated notable recovery at a six-month follow-up. …”
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570
A Rapidly Enlarging Squamous Inclusion Cyst in an Axillary Lymph Node following Core Needle Biopsy
Published 2012-01-01“…The specimen revealed fragmented squamous epithelium surrounded by lymphoid tissue consistent with a squamous inclusion cyst in a lymph node, but a metastatic squamous cell carcinoma could not be excluded. …”
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571
Pancreas Proapoptotic Proteases in Patients with Chronic Pancreatitis
Published 2019-06-01“…Thus, DNase I is expressed in the cytoplasm of acinar cells, while endonuclease G is most typical for insular cells and those in the epithelium of the ducts. This proves the existence of various apoptosis mechanisms in the exo- and endocrine portions of the pancreas.…”
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572
Effects of refraction and axial length on the development and progression of diabetic retinopathy
Published 2021-12-01“…The third authors argue a focal disintegration of retinal pigment epithelium to eliminate metabolic end products through the choroid and sclera. …”
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573
Poly-L-Arginine Induces Apoptosis of NCI-H292 Cells via ERK1/2 Signaling Pathway
Published 2018-01-01“…Cationic protein is a cytotoxic protein secreted by eosinophils and takes part in the damage of airway epithelium in asthma. Poly-L-arginine (PLA), a synthetic cationic protein, is widely used to mimic the biological function of the natural cationic protein in vitro. …”
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574
PEDF Overexpression Ameliorates Cardiac Lipotoxicity in Diabetic Cardiomyopathy via Regulation of Energy Metabolism
Published 2025-01-01“…The excessive accumulation of lipid metabolic intermediates within the myocardium can lead to increased production of reactive oxygen species (ROS) and promote apoptosis. Pigment epithelium-derived factor (PEDF) has been shown to regulate cardiac energy metabolism; however, its role in modulating energy metabolism, ROS generation, and apoptosis in the context of DCM requires further investigation.Methods: PEDF was overexpressed in db/db mice via tail vein injection of adeno-associated virus 9(AAV9)-PEDF. …”
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575
Initiation of ART during early acute HIV infection preserves mucosal Th17 function and reverses HIV-related immune activation.
Published 2014-12-01“…Mucosal Th17 cells play an important role in maintaining gut epithelium integrity and thus prevent microbial translocation. …”
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576
Responses of Multipotent Retinal Stem Cells to IL-1β, IL-18, or IL-17
Published 2015-01-01“…As a comparison, primary mouse retinal pigment epithelium (RPE) cells were also treated with IL-1β, IL-18, or IL-17A and analyzed for the expression of Il-6 and Il-17rc. …”
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577
Microscopic Observation of Proliferative Membranes in Fibrocontractive Retinal Disorders
Published 2019-01-01“…The detection of pigments in specific types of ERM, like those associated with lamellar macular hole (LMH) or secondary to retinal detachment (RD), diabetes, and PVR, suggested that retinal pigment epithelium (RPE) cells may have a role in the development of these vitreoretinal disorders. …”
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578
Generation of a BEST1 Pr-EGFP reporter human embryonic stem cell line via CRISPR/Cas9 editing
Published 2025-02-01“…The retinal pigment epithelium (RPE) cell, located between the neural retina and choriocapillaris, is vital for retinal maintenance and photoreceptor function. …”
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579
Saffron's protective role against atherosclerosis-induced cataract progression in New Zealand white rabbits with phytochemical analysis of saffron's extract.
Published 2025-01-01“…Additionally, a uniform layer of anterior epithelium and decreased non-swollen lens fibers indicated significant cataract lesion improvement. …”
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580
miR-126 Mimic Counteracts the Increased Secretion of VEGF-A Induced by High Glucose in ARPE-19 Cells
Published 2021-01-01“…Since levels of miR-126 have been found downregulated in diabetes, this study is aimed at investigating whether hyperglycemia affects expression of miR-126 in a retinal pigment epithelium cell line. ARPE-19 cells were transfected with miR-126 inhibitor or with miR-126 mimic and the respective scramble negative control. …”
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