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    Augmentation of Tonic GABAA Inhibition in Absence Epilepsy: Therapeutic Value of Inverse Agonists at Extrasynaptic GABAA Receptors by Adam C. Errington, David W. Cope, Vincenzo Crunelli

    Published 2011-01-01
    “…These results challenge the existing theory that typical absence seizures are underpinned by a widespread loss of GABAergic function in thalamocortical circuits and illustrate a vital role for astrocytes in the pathology of typical absence epilepsy. Moreover, they explain why pharmacological agents that enhance GABA receptor function can initiate or exacerbate absence seizures and suggest a potential therapeutic role for inverse agonists at eGABAARs in absence epilepsy.…”
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    Level of Acceptance of Illness and Its Association with Quality of Life among Patients with Epilepsy in North Shewa, Ethiopia by Yonas Teshome, Yerukneh Solomon, Feredegn Talargia, Negese Worku, Abreham Shitaw, Abebaye Aragaw Leminie

    Published 2022-01-01
    “…A total of 78 patients with epilepsy aged more than 18 years were randomly selected and assessed using Quality of Life in Epilepsy Inventory 31 and acceptance of illness scale. …”
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    Histopathological and Biochemical Assessment of Neuroprotective Effects of Sodium Valproate and Lutein on the Pilocarpine Albino Rat Model of Epilepsy by Aziza Rashed Al-Rafiah, Khlood Mohammed Mehdar

    Published 2021-01-01
    “…Epilepsy is one of the most frequent neurological disorders characterized by an enduring predisposition to generate epileptic seizures. …”
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    How do smoking, vaping, and nicotine affect people with epilepsy and seizures? A scoping review protocol. by Jackson A Narrett, Waleed Khan, Melissa C Funaro, Jeremy J Moeller

    Published 2023-01-01
    “…<h4>Background</h4>Epilepsy is a prevalent disease that requires personalized care to control seizures, reduce side effects, and ameliorate the burden of comorbidities. …”
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    Clinical efficacy of low‐dose Perampanel correlates with neurophysiological changes in familial adult myoclonus epilepsy 2 by Antonietta Coppola, Claudia Cuccurullo, Gianmaria Senerchia, Marica Rubino, Liana Veneziano, Francesco Brancati, Luigi Baratto, Valentina Virginia Iuzzolino, Leonilda Bilo, Pasquale Striano, Raffaele Dubbioso

    Published 2025-02-01
    “…Abstract Familial adult myoclonus epilepsy (FAME) management relies on antiseizure medications (ASMs), which inadequately address myoclonus and cortical tremor. …”
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    The Effectiveness of Modified Atkins Ketogenic Diet on Children with Intractable Epilepsy: A Pilot Study from Indonesia by Achmad Rafli, Setyo Handryastuti, Mulya Rahma Karyanti, Yoga Devaera, Cut Nurul Hafifah, Irawan Mangunatmadja, Muzal Kadim, Elisabeth Siti Herini, Lora Sri Nofi, Ariek Ratnawati, Suci Fitrianti

    Published 2023-01-01
    “…The ketogenic diet has recently been explored as a potential treatment approach for intractable epilepsy in children and has been applied in various parts of the world. …”
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    Correlation between selenium levels and selenoproteins expression in idiopathic generalized epilepsy: a study from Karachi by Hareem Nisar, Rafat Amin, Sadaf Khan, Tehseen Fatima, Qamar-Un-Nisa, Jawwad-Us-Salam

    Published 2025-01-01
    “…Abstract Background Oxidative damage has been implicated in multiple neurodegenerative diseases, including epilepsy. Selenium, in the form of selenoproteins is an integral part of the human antioxidant defense system. …”
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    Prevalence of Provocative Seizures in Persons with Epilepsy: A Longitudinal Study at Khon Kaen University Hospital, Thailand by Nutthaya Vongkasamchai, Sunee Lertsinudom, Acharawan Topark-Ngarm, Udomlack Peansukwech, Kittisak Sawanyawisuth, Somsak Tiamkao, Integrated Epilepsy Research Group

    Published 2015-01-01
    “…Provocative factors are one causative factor of seizure attacks in persons with epilepsy (PWE). There are limited data of prevalence and major provocative factors in Asian populations. …”
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