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    Rare seizure presentation in 3-year-old male: Case of focal epilepsy associated with squatting and running by Zayan Musa, Abhijnya Gowder, Herlinda Bergman, Roopa Viraraghavan

    Published 2025-07-01
    “…We report the case of a 3-year-old male initially observed to have breath-holding spells, squatting, and spontaneous crying who later developed symptoms of atypical seizures suggestive of focal epilepsy. Electroencephalogram confirmed focal seizures, while MRI revealed periventricular leukomalacia. …”
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    Post-processing of a distributed source method for the localization of somatosensory cortex in a cohort of epilepsy patients by Kevin Tyner, Matthew McCumber, Srijita Das, Carmen Urban, Anthony J. Maxin, Tiffany Chu, Mustaffa Alfatlawi, Stephen V. Gliske

    Published 2024-06-01
    “…Localizing eloquent cortices is crucial for many neurosurgical applications, such as epilepsy and tumor resections. Clinicians may use non-invasive methods such as magnetoencephalography (MEG) to localize these cortical regions using equivalent current dipoles (ECDs). …”
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    Evaluation of Presumably Disease Causing SCN1A Variants in a Cohort of Common Epilepsy Syndromes. by Dennis Lal, Eva M Reinthaler, Borislav Dejanovic, Patrick May, Holger Thiele, Anna-Elina Lehesjoki, Günter Schwarz, Erik Riesch, M Arfan Ikram, Cornelia M van Duijn, Andre G Uitterlinden, Albert Hofman, Hannelore Steinböck, Ursula Gruber-Sedlmayr, Birgit Neophytou, Federico Zara, Andreas Hahn, Genetic Commission of the Italian League against Epilepsy, EuroEPINOMICS CoGIE Consortium, Padhraig Gormley, Felicitas Becker, Yvonne G Weber, Maria Roberta Cilio, Wolfram S Kunz, Roland Krause, Fritz Zimprich, Johannes R Lemke, Peter Nürnberg, Thomas Sander, Holger Lerche, Bernd A Neubauer

    Published 2016-01-01
    “…Variants are more likely to be classified as pathogenic if they have already been identified previously in a patient with epilepsy. Here, we critically re-evaluate the pathogenicity of this class of variants in a cohort of patients with common epilepsy syndromes and subsequently ask whether a significant fraction of benign variants have been misclassified as pathogenic.…”
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    Low levels of maximal aerobic power impair the profile of mood state in individuals with temporal lobe epilepsy by Rodrigo Luiz Vancini, Claudio Andre Barbosa de Lira, Marília dos Santos Andrade, Cristiano de Lima, Ricardo Mario Arida

    Published 2015-01-01
    “…Objective To investigate the correlation between cardiorespiratory fitness and mood state in individuals with temporal lobe epilepsy (TLE). …”
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    A novel method for optimizing epilepsy detection features through multi-domain feature fusion and selection by Guanqing Kong, Guanqing Kong, Shuang Ma, Shuang Ma, Wei Zhao, Wei Zhao, Haifeng Wang, Haifeng Wang, Qingxi Fu, Qingxi Fu, Jiuru Wang

    Published 2024-11-01
    “…Consequently, this optimized method for epilepsy seizure detection enhances the diagnostic accuracy of epilepsy seizures.…”
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    Value of Functionalized Superparamagnetic Iron Oxide Nanoparticles in the Diagnosis and Treatment of Acute Temporal Lobe Epilepsy on MRI by Tingting Fu, Qingxia Kong, Huaqiang Sheng, Lingyun Gao

    Published 2016-01-01
    “…Although active targeting of drugs using a magnetic-targeted drug delivery system (MTDS) with superparamagnetic iron oxide nanoparticles (SPIONs) is a very effective treatment approach for tumors and other illnesses, successful results of drug-resistant temporal lobe epilepsy (TLE) are unprecedented. A hallmark in the neuropathology of TLE is brain inflammation, in particular the activation of interleukin-1β (IL-1β) induced by activated glial cells, which has been considered a new mechanistic target for treatment. …”
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