Chinese Family With Knobloch Syndrome Associated With a Novel PAK2 Variant Leading to Reduced Phosphorylation Levels by Liwei Shen, Xiaofei Ye, Xiaocui Wang, Conglei Song, Bin Yang

“…Methods This study included a Chinese family with a proband who primarily presented with epilepsy and developmental delay. Whole‐exome sequencing and Sanger sequencing were performed to analyze potential variants. …”
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Somatic and stomatological status of patients with oncopathology of the maximumface area by Sh. F. Dzhuraeva, A. V. Ikonnikova

“…The share of neuropsychiatric disorders (epilepsy), infections (HIV) is small. During the screening survey conducted on the basis of the surgical and radiological departments of the Ivanovo Regional Oncologic Dispensary, it turned out that the main factors contributing to the development of tumor processes were: middle-aged people – poor oral hygiene (60%); sharp edges of damaged teeth (24%), poorly made restorations, fillings (16%); elderly people – poorly made orthopedic structures (86%). …”
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Effects of Night-Time Use of Rotigotine on Nocturnal Symptoms in Parkinson’s Disease by Francesc Vallderiola, Yaroslau Compta, Javier Aparicio, Jaume Tarradellas, Gabriel Salazar, Josep María Oliver, Antonio Callén, Tania Delgado, Fritz Nobbe

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Neuroglobin: A promising candidate to treat neurological diseases by Ivan Millan Yañez, Isabel Torres-Cuevas, Marisol Corral-Debrinski

“…Autism spectrum disorder, motor neuron disease, encephalopathy, epilepsy, stroke, ataxia, Alzheimer’s disease, amyotrophic lateral sclerosis, Huntington’s disease, and Parkinson’s disease represent a non-exhaustive list of neurological illnesses. …”
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Geographic correlation between tapeworm carriers and heavily infected cysticercotic pigs. by Seth E O'Neal, Luz M Moyano, Viterbo Ayvar, Guillermo Gonzalvez, Andre Diaz, Silvia Rodriguez, Patricia P Wilkins, Victor C W Tsang, Robert H Gilman, Hector H Garcia, Armando E Gonzalez, Cysticercosis Working Group in Peru

“…<h4>Background</h4>Neurocysticercosis is a leading cause of preventable epilepsy in the developing world. Sustainable community-based interventions are urgently needed to control transmission of the causative parasite, Taenia solium. …”
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Exploring the Drug Repurposing Versatility of Valproic Acid as a Multifunctional Regulator of Innate and Adaptive Immune Cells by Rodolfo Soria-Castro, Alejandro Schcolnik-Cabrera, Gloria Rodríguez-López, Marcia Campillo-Navarro, Nahum Puebla-Osorio, Sergio Estrada-Parra, Iris Estrada-García, Rommel Chacón-Salinas, Alma D. Chávez-Blanco

“…Valproic acid (VPA) is widely recognized for its use in the control of epilepsy and other neurological disorders in the past 50 years. …”
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Timing of benzodiazepine treatment and mortality in adult patients with generalized convulsive status epilepticus by Au Auvichayapat, Verajit Chotmongkol, Kittisak Sawanyawisuth, Somsak Tiamkao

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Assessment of ChatGPT’s performance on neurology written board examination questions by Patrick Kearns, Arthur Wang, Demetrius Maraganore, Aaron Dumont, Evan Multala, Johnny Delashaw, Tse Chiang Chen

“…The highest performing subjects were pain (100%), epilepsy &amp; seizures (85%) and genetic (82%) while the lowest performing subjects were imaging/diagnostic studies (27%), critical care (41%) and cranial nerves (48%).Discussion This study found that ChatGPT performed similarly to its human counterparts. …”
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Awake Craniotomy in a Child: Assessment of Eligibility with a Simulated Theatre Experience by Jason Labuschagne, Clover-Ann Lee, Denis Mutyaba, Tatenda Mbanje, Cynthia Sibanda

“…Awake craniotomy is a useful surgical approach to identify and preserve eloquent areas during tumour resection, during surgery for arteriovenous malformation resections and for resective epilepsy surgery. With decreasing age, a child’s ability to cooperate and mange an awake craniotomy becomes increasingly relevant. …”
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Stimulation mapping and whole-brain modeling reveal gradients of excitability and recurrence in cortical networks by Davide Momi, Zheng Wang, Sara Parmigiani, Ezequiel Mikulan, Sorenza P. Bastiaens, Mohammad P. Oveisi, Kevin Kadak, Gianluca Gaglioti, Allison C. Waters, Sean Hill, Andrea Pigorini, Corey J. Keller, John D. Griffiths

“…We investigated this question using rare simultaneous multimodal electrophysiology (stereotactic and scalp electroencephalography - EEG) recordings in 36 patients with drug-resistant focal epilepsy during presurgical intracerebral electrical stimulation (iES) (323 stimulation sessions). …”
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Prediction of seizure recurrence using electroencephalogram analysis with multiscale deep neural networks before withdrawal of antiepileptic drugs by Lung-Chang Lin, Ming-Yuh Chang, Yi-Hung Chiu, Ching-Tai Chiang, Rong-Ching Wu, Rei-Cheng Yang, Chen-Sen Ouyang

“…A total of 60 patients with epilepsy were divided into two groups (30 in the recurrence group and 30 in the non-recurrence group). …”
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Out-of-hospital multimodal seizure detection: a pilot study by Martin Ballegaard, Troels Wesenberg Kjær, Ivan Chrilles Zibrandtsen, Jonas Munch Nielsen, Ástrós Eir Kristinsdóttir, Paolo Masulli, Tobias Søren Andersen

“…Background Out-of-hospital seizure detection aims to provide clinicians and patients with objective seizure documentation in efforts to improve the clinical management of epilepsy. In-patient studies have found that combining different modalities helps improve the seizure detection accuracy. …”
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Abnormal glycogen chain length pattern, not hyperphosphorylation, is critical in Lafora disease by Felix Nitschke, Mitchell A Sullivan, Peixiang Wang, Xiaochu Zhao, Erin E Chown, Ami M Perri, Lori Israelian, Lucia Juana‐López, Paola Bovolenta, Santiago Rodríguez de Córdoba, Martin Steup, Berge A Minassian

“…Abstract Lafora disease (LD) is a fatal progressive epilepsy essentially caused by loss‐of‐function mutations in the glycogen phosphatase laforin or the ubiquitin E3 ligase malin. …”
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Neuroprotection by Mitochondrial NAD Against Glutamate-Induced Excitotoxicity by Bruna S. Paiva, Diogo Neves, Diogo Tomé, Filipa J. Costa, Inês C. Bruno, Diogo Trigo, Raquel M. Silva, Ramiro D. Almeida

“…Excitotoxicity is a pathological process that occurs in many neurological diseases, such as stroke or epilepsy, and is characterized by the extracellular accumulation of high concentrations of glutamate or other excitatory amino acids (EAAs). …”
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Patient demographics, clinical characteristics and genetic mutations of DMD and BMD patients in Qatar Epidemiological and genetic profile of Duchenne muscular dystrophy and Becker... by Mohammad Sawahreh, Fatima Al-Maadid, Khalid Omer Ibrahim, Tawfeg Ben Omran, Mahmoud Fawzi Osman

“…CK was elevated in 36/37 (range: 2,300–45,000 U/L). Epilepsy was documented in 3 patients; 3 had autism and 1 had ADHD. …”
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Characterizing the Prevalence of Psychiatric Conditions and Fear-Potentiated Startle Response in Civilians with a History of Trauma and Seizures by Trinidi Prochaska, Helena Zeleke, Sean T. Minton, Abigail Powers, Vasiliki Michopoulos, Jon T. Willie, Daniel L. Drane, Tanja Jovanovic, Sanne J.H. van Rooij

“…Existing knowledge of the overlapping neurocircuitry between seizure activity in limbic regions (eg, medial temporal lobe epilepsy) and PTSD also suggests that people with seizure histories may exhibit PTSD-like alterations in their fear-potentiated startle (FPS) responses. …”
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THE RESULTS OF LONG-TERM STUDY OF HERPESVIRUS INFECTION AT THE DEPARTMENT OF INFECTIOUS DISEASES IN CHILDREN OF RUSSIAN NATIONAL RESEARCH MEDICAL UNIVERSITY by O. V. Shamsheva, F. S. Kharlamova, N. Yu. Egorova, O. V. Molochkova, E. V. Novosad, E. V. Simonova, T. M. Lebedeva, N. A. Guseva

“…Children with diagnoses such as convulsive syndrome, epilepsy, neuropathy need a comprehensive examination (ELISA, PCR, Indirect immunofluorescence reaction) to identify markers of active replication of herpes viruses, with an emphasis on the detection of HHV6. …”
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Exploring gene-phenotype relationships in GRIN-related neurodevelopmental disorders by Jong Ho Cha, Jee Min Kim, Hee-Jeong Yun, Hyungjin Chin, Hye Jin Kim, Woojoong Kim, Soo Yeon Kim, Byung Chan Lim, Ki Joong Kim, Seungbok Lee, Jong-Hee Chae

“…Abstract The GRIN family is implicated in neurological disorders, such as global developmental delay (GDD) and epilepsy. We reviewed 31 patients with GRIN-related neurodevelopmental disorders at Seoul National University Hospital; all exhibited profound GDD, with 58.1% unable to walk independently and 74.2% unable to speak meaningful words. …”
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Real-world safety profile of live attenuated Japanese encephalitis vaccine before and after the vaccine administration law. by Chao Zhang, Yan Liu, Xiaofu Luo, Liping Han, Jianyong Shen

“…There were only 2 severe reactions reported: thrombocytopenia and epilepsy.<h4>Conclusions</h4>The implementation of the LAW significantly enhanced the surveillance capacity and sensitivity for AEFIs associated with JEV-L. …”
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Social frustratedness as a psychogenesis factor of adjustment disorders by L. I. Wasserman, O. Yu. Shchelkova, E. A. Dubinina, M. A. Berebin, V. A. Mikhailov, E. A. Nikiforova, D. N. Chugunov

“…Socio-diagnostic criteria are illustrated by examples of the practical use in medical psychodiagnostics of social frustration in teachers of mass schools, the military and in patients with focal epilepsy. The specified research contingent is united by the problem of stress resistance in crisis situations (including a disease situation and the attitude to the disease). …”
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