Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting by Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder

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Cannabis sativa subsp. sativa's pharmacological properties and health effects: A scoping review of current evidence. by Xin Yi Lim, Terence Yew Chin Tan, Siti Hajar Muhd Rosli, Muhammad Nor Farhan Sa'at, Syazwani Sirdar Ali, Ami Fazlin Syed Mohamed

“…There was also evidence suggesting benefits in cannabis dependence, epilepsy, and anxiety disorders. Pre-clinically, hemp derivatives showed potential anti-oxidative, anti-hypertensive, anti-inflammatory, anti-diabetic, anti-neuroinflammatory, anti-arthritic, anti-acne, and anti-microbial activities. …”
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Subdural empyema in patient with SARS-CoV-2 positivity: A rare case report of 3 patients by Hamidreza Aghadoost, MD, Ghazaleh Salehabadi, MD-MPH, Esmaeil Fakharian, MD

“…The third one is a 47-year-old gentleman with a known case of epilepsy, who presented with a 2-day history of headache and fever and an event of Generalized Tonic Colonic (GTC) seizure on the day of admission. …”
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Cerebellar cognitive affective syndrome in patients with spinocerebellar ataxia type 10. by Angel Omar Romero-Molina, Gabriel Ramirez-Garcia, Amanda Chirino-Perez, Gustavo Padron-Rivera, Carlos Roberto Hernandez-Castillo, Maria Guadalupe Garcia-Gomar, Diana Laura Torres-Vences, Juan Fernandez-Ruiz

“…<h4>Background</h4>Spinocerebellar ataxia type 10 (SCA10) is an autosomal dominant cerebellar ataxia, characterized by epilepsy, ataxic symptoms, and cognitive impairments linked to Cerebellar Cognitive Affective Syndrome (CCAS). …”
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Expression of toll like receptor 8 (TLR8) in specific groups of mouse hippocampal interneurons. by Lennart Seizer, Sadegh Rahimi, Sandra Santos-Sierra, Meinrad Drexel

“…High expression of TLR8 in parvalbumin-interneurons may contribute to their high vulnerability in human temporal lobe epilepsy.…”
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Cortical spreading depression produces a neuroprotective effect activating mitochondrial uncoupling protein-5 by Viggiano E, Monda V, Messina A, Moscatelli F, Valenzano A, Tafuri D, Cibelli G, De Luca B, Messina G, Monda M

“…Emanuela Viggiano,1,2 Vincenzo Monda,1 Antonietta Messina,1 Fiorenzo Moscatelli,3 Anna Valenzano,3 Domenico Tafuri,4 Giuseppe Cibelli,3 Bruno De Luca,1 Giovanni Messina,1,3 Marcellino Monda1 1Department of Experimental Medicine, Section of Human Physiology and Unit of Dietetics and Sports Medicine, Second University of Naples, Naples, 2Department of Medicine, University of Padua, Padua, 3Department of Clinical and Experimental Medicine, University of Foggia, Foggia, 4Department of Motor Sciences and Wellness, University of Naples &amp;ldquo;Parthenope&amp;rdquo;, Naples, Italy Abstract: Depression of electrocorticogram propagating over the cortex surface results in cortical spreading depression (CSD), which is probably related to the pathophysiology of stroke, epilepsy, and migraine. However, preconditioning with CSD produces neuroprotection to subsequent ischemic episodes. …”
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Long-Lasting Effects of GABA Infusion Into the Cerebral Cortex of the Rat by Teresa Montiel, Daniel Almeida, Iván Arango, Eduardo Calixto, César Casasola, Simón Brailowsky

“…The long-lasting effects of tonic GABAA receptor stimulation may be involved in long-term information storage processes at the cortical level, whereas the cessation of GABAA receptor stimulation may be involved in chronic pathological conditions, such as epilepsy. Furthermore, we propose that GWS may represent a common key factor in the addiction to GABAergic agents (for example, barbiturates, benzodiazepines, and ethanol). …”
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FDA-approved phensuximide inhibits RIPK1-dependent immunogenic cell death by Byeong-Ju Kim, Sun Mi Hong, Hyun-Jin Noh, Jihye Kim, Su-Yeon Seon, Jeong-Eun Lee, Da-Hye Jeong, Ju-Mi Park, Sejeong Park, Sanghoon Lee, Jaewoo Kang, Dakeun Lee, Michael J. Morgan, You-Sun Kim

“…Importantly, phensuximide, which has already been approved by the FDA for the treatment of epilepsy, effectively prevents the kinase activity of RIPK1 without affecting the NF-κB and MAPK pathways. …”
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Cysteine leukotrienes as key mediators of immune-dependent diseases and the therapeutic potential of the leukotriene receptor antagonist (montelukast). Part 1 by N. G. Astafieva, I. E. Mikhailova, E. O. Gaisina, I. A. Perfilova, E. N. Udovichenko

“…Through pharmacological and genetic studies, cysteinyl leukotriene receptors have been shown to be involved in the pathogenesis of Alzheimer's disease and other neurodegenerative/neurological diseases such as Parkinson's disease, multiple sclerosis and epilepsy. This updated review will also highlight research into the therapeutic potential of montelukast beyond clinical guidelines for rhinitis and asthma.…”
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Pharmacological Investigations of the Dissociative 'Legal Highs' Diphenidine, Methoxphenidine and Analogues. by Jason Wallach, Heather Kang, Tristan Colestock, Hamilton Morris, Zuner A Bortolotto, Graham L Collingridge, David Lodge, Adam L Halberstadt, Simon D Brandt, Adeboye Adejare

“…1,2-Diarylethylamines including lanicemine, lefetamine, and remacemide have clinical relevance in a range of therapeutic areas including pain management, epilepsy, neurodegenerative disease and depression. …”
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Multimorbidity and associated outcomes among older adult inpatients with neurological disorders by Aroldo BACELLAR, Telma ASSIS, Bruno Bacellar PEDREIRA, Luan CÔRTES, Silas SANTANA, Osvaldo José Moreira do NASCIMENTO

“…Multimorbidity was detected in 92.61% (739) of patients, with a mean of 3.88±1.67 (median: 4.0), ranging from 2 to 10 chronic diseases. Patients with epilepsy, dementia, and movement disorders had the highest degrees of clusters of chronic morbidities (>50% of them with ≥5 chronic disorders), followed by those with cerebrovascular and neuromuscular disorders. …”
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CELF4 regulates translation and local abundance of a vast set of mRNAs, including genes associated with regulation of synaptic function. by Jacy L Wagnon, Michael Briese, Wenzhi Sun, Connie L Mahaffey, Tomaž Curk, Gregor Rot, Jernej Ule, Wayne N Frankel

“…Mice deficient for neuronal RNA-binding protein CELF4 have a complex neurological disorder with epilepsy as a prominent feature. Human CELF4 has recently been associated with clinical features similar to those seen in mutant mice. …”
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Exploring the Effectiveness of Machine Learning and Deep Learning Techniques for EEG Signal Classification in Neurological Disorders by Souhaila Khalfallah, William Puech, Mehdi Tlija, Kais Bouallegue

“…This study explores the use of machine learning (ML) and deep learning (DL) techniques in processing Electroencephalography (EEG) signals to detect various neurological disorders, including Epilepsy, Autism Spectrum Disorder (ASD), and Alzheimer&#x2019;s disease. …”
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Bibliometric analysis of transition readiness in adolescents with chronic diseases by Yao Zhang, Xuewei Chen, Yi Qi, Yiwen Hu, Ziling Xie, Chaoqun Dong

“…The hot topics about the transition readiness of adolescents with chronic diseases can be summarized as follows: adolescents with sickle cell disease, epilepsy, crohn's disease, transplantation and neurogastroenterology-related diseases, the validation of The Self-Management and Transition to Adult Treatment Questionnaire, the crucial role of parents, care coordination, vocational readiness, quality of life, and health literacy. …”
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Neurodevelopmental disorders at Chris Hani Baragwanath Academic Hospital: a 4-year retrospective database review by Sarah Jane Lowick, Sibongile Mbatha

“…Comorbidity included cerebral palsy (11.4%), epilepsy (16.1%), hearing (5.2%) and visual impairment (5.5%). …”
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Parents care needs with epileptic children: a hybrid model concept analysis by A. Khalili, F. Cheraghi, A. Fayyazi, A. R. Soltanian, Farshid Shamsaei

“…This study aimed to analyze the concept of parental care needs for children with epilepsy. Methods This study was conducted using the hybrid method in three phases. …”
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Is it worth a CGH array? MBD5 haploinsufficiency and clinical variability in MBD5-associated neurodevelopmental disorder: a case report by Federica Trentin, Tullio Messana, Giulia J. Leone, Pamela Magini, Marco Seri, Duccio M. Cordelli

“…She underwent an inconclusive target next-generation sequencing (NGS) of 43 known epilepsy-associated genes. Further investigation using array-CGH revealed a mosaic 407 kb deletion at 2q23.1 encompassing the MBD5 (methyl-CpG-binding domain protein 5) gene. …”
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Multi-metal oxide/N-doped reduced graphene oxide modified electrode for ultrasensitive determination of phenobarbital by Seyed Saman Nemati, Gholamreza Dehghan, Simin Khataee, Zohreh Shaghaghi

“…Phenobarbital (PB) is known for its sedative and anticonvulsant characteristics, making it a critical agent for the management of epilepsy and seizure disorders. Considering its narrow therapeutical range, accurate monitoring of this drug is highly recommended to prevent side effects. …”
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Antiepileptic drugs and foetal disorders: analysis of 20-year data from the pharmacovigilance center by Zejun Ji, Jianjun Nie, Qingli Shen, Zhonghua Fu

“…BackgroundFor women of childbearing age, the risks of uncontrolled epilepsy to the mother and fetus need to be balanced against the potential teratogenic effects of antiepileptic drugs (AEDs). …”
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Coexisting Disorders and Problems in Preschool Children with Autism Spectrum Disorders by Lotta Höglund Carlsson, Fritjof Norrelgen, Liselotte Kjellmer, Joakim Westerlund, Christopher Gillberg, Elisabeth Fernell

“…Information on autistic symptoms, general cognitive function, speech and language, motor function, epilepsy, vision, hearing, activity level, behavior, and sleep was collected. …”
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