Suggested Topics within your search.
Suggested Topics within your search.
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3641
Cardiac Glycosides: From Natural Defense Molecules to Emerging Therapeutic Agents
Published 2025-06-01“…In the nervous system, CGs modulate neuroinflammation, support synaptic plasticity, and improve cognitive function in models of Alzheimer’s disease, epilepsy, and multiple sclerosis. Despite their therapeutic potential, clinical translation is hindered by narrow therapeutic indices and systemic toxicity. …”
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3642
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3643
Machine learning and deep learning in medicine and neuroimaging
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3644
Downregulated GABA and BDNF-TrkB Pathway in Chronic Cyclothiazide Seizure Model
Published 2014-01-01“…Thus, CTZ seizure rats may provide a novel animal model for epilepsy study and anticonvulsant drug testing in the future.…”
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3645
Ultrasensitive Detection of Neurotransmitter in Neurological Disorders
Published 2024-12-01“…Among all the neurological diseases the most prevalent one in Pakistani population are: depression (6%), schizophrenia (1.5%) and epilepsy (1-2%). Dopamine, a critical neurotransmitter plays an important role in onset and progression of aforementioned disorders. …”
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3646
Self-Supervised Learning to Unveil Brain Dysfunctional Signatures in Brain Disorders: Methods and Applications
Published 2025-01-01“…We showcase successful applications of these techniques in understanding and classifying conditions such as Alzheimer’s disease, Parkinson’s disease, and epilepsy, demonstrating their potential in downstream neuropsychological applications. …”
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3647
A closed loop fully automated wireless vagus nerve stimulation system
Published 2025-07-01“…Abstract Vagus nerve stimulation (VNS) has been explored as a treatment for a range of conditions, including epilepsy, cardiovascular disorders, drug-resistant depression, chronic pain, and obesity. …”
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3648
The protective effect of DMI on hippocampus EEG, behavioral and biochemical parameters in hypoxia-induced seizure on neonatal period.
Published 2024-01-01“…Hypoxia-Induced Neonatal Seizure (HINS) is a prevalent type of seizure in infants caused by hypoxic conditions, which can lead to an increased risk of epilepsy, learning disabilities, and cognitive impairments later in life. …”
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3649
Cognitive functions, epileptic syndromes and antiepileptic drugs
Published 1992-03-01“…We evaluated 7 patients with symptomatic localised epilepsies (SEL) on phenytoin aged 30±12 (mean±standard deviation) years, 8 with idiopathic generalised epilepsies on sodium valproate aged 18±4 years, 16 with SEL on carbamazepine aged 28±11 years, and 35 healthy controls aged 27±11 years. …”
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3650
Drug treatment alters performance in a neural microphysiological system of information processing
Published 2025-06-01“…Hyperactive glutamatergic dysregulation is linked to neurological disorders including epilepsy, and inducible overexpression of neurogenin 2 (NGN2) in human induced pluripotent stem cells (hiPSCs) generates glutamatergic cultures with dysregulated hyperactivity. …”
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3651
Right Pulmonary Cyst in the Child with Central Nervous System Damage: Clinical Case
Published 2020-02-01“…The child (11 y 10 m) was diagnosed with pulmonary cyst in the right lung with local pneumothorax and alongside with congenital developmental brain malformation and symptomatic epilepsy. The first episode of severe acute right-sided pneumonia was diagnosed at the age of 11 y 7 m, he was on hospital stay at place of residence for two weeks. …”
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3652
Models of neuroinflammation for the assessment of kappa-opioid receptor ligands
Published 2023-05-01“…The development of new drugs to combat neuroinflammation is highly relevant as it opens up possibilities for the treatment of a wide range of diseases, including Alzheimer’s disease, Parkinson’s disease, epilepsy, schizophrenia, depression, and others. Kappa-opioid agonists represent a promising class of compounds with а high potential to be used in the treatment of neurological conditions accompanied by neuroinflammation.The aim of the study was to provide a summary of the current strategies employed to evaluate the neurotropic anti-inflammatory effects of kappa-opioid ligands in laboratory animals with induced neuroinflammation.Materials and methods. …”
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3653
Neonatal neuronal WWOX gene therapy rescues Wwox null phenotypes
Published 2021-11-01“…We recently demonstrated that neuronal ablation of murine Wwox recapitulates phenotypes of Wwox‐null mice leading to intractable epilepsy, hypomyelination, and postnatal lethality. …”
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3654
A Case of Primary Hypoparathyroidism Presenting with Acute Kidney Injury Secondary to Rhabdomyolysis
Published 2016-01-01“…He had been treated for epilepsy for the last 10 years. He was admitted to the emergency department for leg pain, cramping in the hands and legs, and agitation multiple times within the last six months. …”
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3655
FCEEG: federated learning-based seizure diagnosis through electroencephalogram (EEG) analysis
Published 2025-12-01“…The data provides detailed insights into brain activity which aids in epilepsy management. Artificial intelligence (AI) and deep learning are widely employed in the analysis of EEG signals to achieve promising classification performance. …”
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3656
<i>SPTAN1</i>-associated developmental and epileptic encephalopathy
Published 2023-09-01“…The article presents the clinical cases of 6 patients with epilepsy, psychomotor and speech developmental delay. …”
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3657
Pandanus odoratissimus (Kewda): A Review on Ethnopharmacology, Phytochemistry, and Nutritional Aspects
Published 2014-01-01“…(family: Pandanaceae) is traditionally recommended by the Indian Ayurvedic medicines for treatment of headache, rheumatism, spasm, cold/flu, epilepsy, wounds, boils, scabies, leucoderma, ulcers, colic, hepatitis, smallpox, leprosy, syphilis, and cancer and as a cardiotonic, antioxidant, dysuric, and aphrodisiac. …”
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3658
Autonoetic Consciousness in Autobiographical Memories after Medial Temporal Lobe Resection
Published 2008-01-01“…This study aims to investigate autonoetic consciousness associated with episodic autobiographical memory in patients who had undergone unilateral medial temporal lobe resection for intractable epilepsy. Autonoetic consciousness, defined as the conscious feeling of mentally travelling back in time to relive a specific event, was assessed using the Remember/Know (R/K) paradigm across different time periods as proposed in the autobiographical memory task developed by Piolino et al. …”
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3659
EVALUATION OF CLINICAL, DEMOGRAPHIC AND ELECTROENCEPHALOGRAPHY FINDINGS OF DRAVET SYNDROME PATIENTS
Published 2021-01-01“…Objective: Dravet syndrome (DS) is a severe myoclonic epilepsy affecting infants and is classified among epileptic syndromes. …”
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3660
The neuroprotective effects of hesperidin and diosmin in neurological disorders via targeting various signaling pathways
Published 2025-07-01“…A scientific literature search was conducted using specific keywords in various databases, including PubMed, Web of Science, Google Scholar, Embase, and Scopus.Diosmin and hesperidin demonstrated protective effects in managing a variety of neurological disorders, such as epilepsy, neuropathy, depression, anxiety, insomnia, autism, glioblastoma, traumatic brain injury, cerebral ischemia-reperfusion, Huntington’s disease, Alzheimer’s disease, Parkinson’s disease, neurotoxicity, and multiple sclerosis through the regulation of various signaling pathways. …”
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