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Suggested Topics within your search.
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3621
Nutritional Studies Evaluating Ketogenic Diets as a Treatment for Obesity and Obesity-Associated Morbidities: Underlying Mechanisms and Potential for Clinical Implementation
Published 2024-12-01“…While the KD is clinically used in pharmacologically refractory epilepsy and specific genetic conditions such as GLUT1 deficiency, recent research suggests that, due to its “fasting mimicking” properties, the KD may also beneficially affect obesity and obesity-associated metabolic diseases. …”
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3622
Stress, epileptiform symptoms in schizophrenia and neural information transmission
Published 2025-05-01“…Several findings indicate that stress may influence epileptiform discharges manifesting in temporal-limbic areas, which may become a potential trigger of psychosis that may manifest without neurologically diagnosed epilepsy. Some findings suggest that measures assessing levels of inter-hemispheric information connection may reveal the spread of subclinical epileptiform neural activity associated with psychotic and seizure-like symptoms. …”
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3623
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3624
Autosomal dominant macrocephaly, acquired with impaired intellectual development: a report of an ultra-rare disease
Published 2025-07-01“…Case presentation A family was referred to genetic counseling due to macrocephaly, drug-resistant epilepsy, and neurodevelopmental delay in a 13-year-old girl. …”
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3625
Acute symptomatic seizure: structural brain lesions, metabolic disorders, anti-seizure medications
Published 2025-03-01“…They differ from unprovoked seizures and epilepsy because the risk of recurrence is significantly lower and there is no long-term predisposition to further seizures. …”
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3626
Pleiotropic Effects of the NSAID Fenamates on Chloride Channels: Opportunity for Ion Channelopathies?
Published 2025-08-01“…Mutations of these proteins are associated with heterogeneous diseases such as myotonia, cystic fibrosis, epilepsy, deafness, lysosomal storage disease, and various kinds of renal and ophthalmic dysfunctions, also known as channelopathies. …”
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3627
Time series segmentation for recognition of epileptiform patterns recorded via microelectrode arrays in vitro.
Published 2025-01-01“…Epilepsy is a prevalent neurological disorder that affects approximately 1% of the global population. …”
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3628
An Ultra-Rare Disorder: Case Report on Cerebrotendinous Xanthomatosis
Published 2025-05-01“…His medical history revealed bilateral cataract surgery in childhood, cognitive decline, epilepsy, and bilateral round swellings of the Achilles tendons, suspected to be xanthomas. …”
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3629
Progressive volume loss and white matter degeneration in cstb-deficient mice: a diffusion tensor and longitudinal volumetry MRI study.
Published 2014-01-01“…Unverricht-Lundborg type progressive myoclonus epilepsy (EPM1, OMIM 254800) is an autosomal recessive disorder characterized by onset at the age of 6 to 16 years, incapacitating stimulus-sensitive myoclonus and tonic-clonic epileptic seizures. …”
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3630
Bone Biochemical Profile of Epileptic Patients Undergoing Anti-Epileptic Drug Therapy in Maiduguri, Nigeria
Published 2022-02-01“…Epilepsy is characterized by repeated seizure which is an excessive discharge or excitation of cerebral cortical neurons causing disturbance in sensation, loss of consciousness and impairment of mental function. …”
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3631
An enhanced CNN-Bi-transformer based framework for detection of neurological illnesses through neurocardiac data fusion
Published 2025-04-01“…In this work, we offer an innovative methodology for predicting mental illnesses such as epilepsy, sleep disorders, bipolar disorder, eating disorders, and depression using a multimodal deep learning framework that integrates neurocardiac data fusion. …”
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3632
Reward recalibrates rule representations in human amygdala and hippocampus intracranial recordings
Published 2024-11-01“…Here, we demonstrate the importance of the amygdala and hippocampus by recording local field potentials directly from these regions intracranially in human epilepsy patients. Reward signals were coded in the high frequency gamma activity (HFG; 60-250 Hz) of both regions and synchronised via low frequency (3-5 Hz) phase-locking only after a shift when patients did not already know the rule and it signalled to stop shifting (“Win-Stay”). …”
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3633
Dynamic imaging of myelin pathology in physiologically preserved human brain tissue using third harmonic generation microscopy.
Published 2025-01-01“…Gray and white matter brain tissue from epilepsy surgery and post-mortem donors was excised. …”
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3634
Glucosinolate Metabolites and Brain Health: An Updated Review on Their Potential Benefits in Neurodegenerative, Neurodevelopmental, and Psychiatric Disorders
Published 2025-07-01“…Neurodegenerative, neurodevelopmental, and psychiatric disorders, as well as epilepsy, affect millions of people. Due to their impact on patients’ quality of life, they represent a major health issue. …”
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3635
Anti-aging versus positive-aging language in scientific literature: Raising questions for future research
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3636
Efficacy of Intravenous Immunoglobulins and Other Immunotherapies in Neurological Disorders and Immunological Mechanisms Involved
Published 2025-05-01“…Disorders such as autoimmune encephalitis, myasthenia gravis, limbic epilepsy, neuropsychiatric systemic lupus erythematosus (NPSLE), and certain forms of schizophrenia have shown clinical responses to immunotherapy, suggesting an underlying autoimmune basis in a subset of patients. …”
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3637
Associations between blood selenium and serum neurofilament light chain: results of a nationwide survey
Published 2025-04-01“…BackgroundSelenium (Se) is essential for many nervous system functions including memory, cognition and coordination, which has also been linked to a variety of neurological disorders, such as epilepsy, Alzheimer’s disease (AD) and Parkinson’s disease (PD). …”
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3638
ATP and MO25alpha regulate the conformational state of the STRADalpha pseudokinase and activation of the LKB1 tumour suppressor.
Published 2009-06-01“…It has recently been demonstrated that a mutation in human STRADalpha that truncates a C-terminal region of the pseudokinase domain leads to the polyhydramnios, megalencephaly, symptomatic epilepsy (PMSE) syndrome. We demonstrate this mutation destabilizes STRADalpha and prevents association with LKB1. …”
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3639
Bullous pemphigoid and its association with neurological diseases
Published 2024-02-01“…This suggests the possibility that the association between BP and neurologic disorders is limited to stroke, epilepsy, and neurodegenerative diseases. Future prospective cohort studies are indicated to further investigate the results of this study. …”
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3640
Effects of anticonvulsant drug on liver enzymes among children in a tribal state of India: A longitudinal study
Published 2023-07-01“…Introduction: Epilepsy is a syndrome of various neurological disorders. …”
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