Kruppel-family zinc finger proteins as emerging epigenetic biomarkers in head and neck squamous cell carcinoma by Patrick Pearson, Kendra Smith, Nilita Sood, Elizabeth Chia, Alicia Follett, Michael B. Prystowsky, Simon Kirby, Thomas J. Belbin

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Epigenetic Changes in Endothelial Progenitors as a Possible Cellular Basis for Glycemic Memory in Diabetic Vascular Complications by Poojitha Rajasekar, Christina L. O’Neill, Lydia Eeles, Alan W. Stitt, Reinhold J. Medina

“…Furthermore, various epigenetic marks have been proposed to closely associate with vascular glycemic memory. …”
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Immune Dysregulation and Cellular Composition in Lichen Sclerosus Revealed by Integrative Epigenetic Analysis with Cell Type Deconvolution by Wang J, Fan H, Bao Z, Li G, Wang L, Zhang D

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A Review of Three Different Studies on Hidden Markov Models for Epigenetic Problems: A Computational Perspective by Kyung-Eun Lee, Hyun-Seok Park

“…Here, we review three HMM-based studies that have contributed to epigenetic research, from a computational perspective. …”
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Inhibition of Mitochondrial Fission Reverses Simulated Microgravity-Induced Osteoblast Dysfunction by Enhancing Mechanotransduction and Epigenetic Modification by Qiusheng Shi, Yaxin Song, Jingqi Cao, Jing Na, Zhijie Yang, Xinyuan Chen, Ziyi Wang, Yubo Fan, Lisha Zheng

“…Moreover, our study showed that SMG-induced chromatin remodeling and histone methylation, which are epigenetic barriers to osteogenic differentiation, can be reversed by targeting mitochondrial fission, further highlighting the significance of mitochondrial dynamics in osteoblast function in an SMG environment. …”
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Mapping chromatin remodelling in glioblastoma identifies epigenetic regulation of key molecular pathways and novel druggable targets by Claire Vinel, James Boot, Weiwei Jin, Nicola Pomella, Alexandra Hadaway, Charles Mein, Nicolae Radu Zabet, Silvia Marino

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Assessment of relationships between epigenetic age acceleration and multiple sclerosis: a bidirectional mendelian randomization study by Hongwei Liu, Hanqing Zhang, Zhaoxu Yin, Miaomiao Hou

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Nucleolar PARP-1 Expression Is Decreased in Alzheimer’s Disease: Consequences for Epigenetic Regulation of rDNA and Cognition by Jianying Zeng, Jenny Libien, Fatima Shaik, Jason Wolk, A. Iván Hernández

“…PARP-1 has been identified as an epigenetic regulator of plasticity and memory. Thus, we hypothesize that PARP-1 may be altered in postmortem hippocampus of individuals with AD compared to age-matched controls without neurologic disease. …”
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The Effects of MicroRNAs on Key Signalling Pathways and Epigenetic Modification in Fibroblast-Like Synoviocytes of Rheumatoid Arthritis by Wenming Hong, Pengying Zhang, Xinming Wang, Jiajie Tu, Wei Wei

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Development of nucleus-targeted histone-tail-based photoaffinity probes to profile the epigenetic interactome in native cells by Yu Wang, Jian Fan, Xianbin Meng, Qingyao Shu, Yincui Wu, Guo-Chao Chu, Rong Ji, Yinshan Ye, Xiangwei Wu, Jing Shi, Haiteng Deng, Lei Liu, Yi-Ming Li

“…Abstract Dissection of the physiological interactomes of histone post-translational modifications (hPTMs) is crucial for understanding epigenetic regulatory pathways. Peptide- or protein-based histone photoaffinity tools expanded the ability to probe the epigenetic interactome, but in situ profiling in native cells remains challenging. …”
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12,13-diHOME Promotes Inflammatory Macrophages and Epigenetically Modifies Their Capacity to Respond to Microbes and Allergens by Din L. Lin, Kevin M. Magnaye, Cara E. Porsche, Sophia R. Levan, Elze Rackaityte, Mustafa Özçam, Susan V. Lynch

“…We hypothesized that macrophages, which are key to both antimicrobial and antigen responses, are functionally and epigenetically modified by 12,13-diHOME leading to short- and long-term dysfunction with consequences for both antimicrobial and antigenic responses. …”
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Epigenetic alterations of 11beta-hydroxysteroid dehydrogenase 1 gene in the adipose tissue of patients with primary aldosteronism by Yoshimichi Takeda, Masashi Demura, Mitsuhiro Kometani, Shigehiro Karashima, Daisuke Aono, Seigo Konishi, Shin-ichi Horike, Makiko Meguro-Horike, Takashi Yoneda, Yoshiyu Takeda

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Editorial: Role of epigenetic modulations and transcription factor in cardiovascular disease and coronary artery spasm: mechanisms and interventions by Ioanna Koniari, Nicholas G. Kounis, Ming-Yow Hung, Ming-Yow Hung, Ming-Yow Hung

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Knockout of the ING5 epigenetic regulator confirms roles in stem cell maintenance and tumor suppression in vivo. by Buthaina Al Shueili, Arthur Dantas, Etienne Mahe, Tak Ho Chu, Yang Yang, Elodie Labit, Eren Kutluberk, Nicolas Lasaleta, Anand Masson, Hiba Omairi, Kenichi Ito, Roman J Krawetz, Rajiv Midha, Gregory Cairncross, Karl Riabowol

“…INhibitor of Growth (ING1-5) proteins are epigenetic readers that target histone acetyltransferase (HAT) or histone deacetylase (HDAC) complexes to the H3K4Me3 mark of active transcription. …”
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N6-Methyladenosine in RNA and DNA: An Epitranscriptomic and Epigenetic Player Implicated in Determination of Stem Cell Fate by Pengfei Ji, Xia Wang, Nina Xie, Yujing Li

“…N6-Methyladenosine modification in DNA (m6dA), mRNA (m6A), tRNA, and other noncoding RNAs has been defined as another important epigenetic and epitranscriptomic marker in eukaryotes in recent years. …”
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ROLE OF THE MODULATORY MEDIATOR SEROTONIN IN THE INDUCTION OF EPIGENETIC PROCESSES DURING LONG TERM MEMORY FORMATION IN HELIX by L. N. Grinkevich, O. V. Vorobiova

Subjects: “…epigenetics…”
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Epigenetic Inhibitors Differentially Impact TGF-β1 Signaling Cascades in COPD Airway Smooth Muscle Cells by Karosham Diren Reddy, Dikaia Xenaki, Ian M. Adcock, Brian G. G. Oliver, Razia Zakarya

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Multichrome encoding-based multiplexed, spatially resolved imaging reveals single-cell RNA epigenetic modifications heterogeneity by Dongsheng Mao, Xiaochen Tang, Runchi Zhang, Song Hu, Hongquan Gou, Penghui Zhang, Wenxing Li, Qiuhui Pan, Bing Shen, Xiaoli Zhu

“…Abstract Understanding the heterogeneity of epigenetic modifications within single cells is pivotal for unraveling the nature of the complexity of gene expression and cellular function. …”
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Parental epigenetic age acceleration and risk of adverse birth outcomes: the Norwegian mother, father and child cohort study by Maria C. Magnus, Yunsung Lee, Ellen Ø. Carlsen, Lise A. Arge, Astanand Jugessur, Liv G. Kvalvik, Nils-Halvdan Morken, Cecilia H. Ramlau-Hansen, Mikko Myrskylä, Per Magnus, Siri E. Håberg

Subjects: “…Epigenetic age…”
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Deciphering the Transcriptional Metabolic Profile of Adipose-Derived Stem Cells During Osteogenic Differentiation and Epigenetic Drug Treatment by Giulia Gerini, Alice Traversa, Fabrizio Cece, Matteo Cassandri, Paola Pontecorvi, Simona Camero, Giulia Nannini, Enrico Romano, Francesco Marampon, Mary Anna Venneri, Simona Ceccarelli, Antonio Angeloni, Amedeo Amedei, Cinzia Marchese, Francesca Megiorni

“…Furthermore, this study underscores the potential of epigenetic drugs like RG108 to enhance ASC properties, paving the way for more effective and personalized cell-based therapies for bone regeneration.…”
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