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59121
Symptom-related experience and sexual health of female patients with pulmonary arterial hypertension: protocol for a systematic review and qualitative meta-synthesis
Published 2025-01-01“…A comprehensive search will encompass seven electronic databases and search engines (Ovid Medline, CINAHL, EMBASE, APA PsycINFO, Cochrane Database of Systematic Reviews, PubMed, Scopus) and grey literature sources (ProQuest Dissertations, ClinicalTrials.gov). …”
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59122
Community perceptions of community health worker effectiveness: Contributions to health behaviour change in an urban health district in South Africa
Published 2024-02-01“…Large-scale, comprehensive CHW programmes at health district level are part of a South African (SA) strategy to re-engineer primary healthcare and take health directly into communities and households, contributing to universal health coverage. …”
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59123
Antibody response to Plasmodium vivax in the context of Epstein-Barr virus (EBV) co-infection: A 14-year follow-up study in the Amazon rainforest.
Published 2025-01-01“…The experimental approach focused on monitoring antibodies to the major blood-stage P. vivax vaccine candidate, the Duffy binding protein region II (DBPII-Sal1), including a novel engineered DBPII-based vaccine targeting conserved epitopes (DEKnull-2). …”
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59124
Working Capital Management Practices and Performance of Small and Medium Enterprises in Western Uganda.
Published 2023“…Small and medium Enterprises (SMEs) are the drivers of Ugandan economy; they are the engine of growth for the economic development, innovation, spur economic prosperity and wealth creation of Uganda. …”
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59127
Study on the Vibroimpact Response of the Particle Elastic Impact on the Metal Plate
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59128
Sparse View CT Reconstruction Algorithm Based on Non-Local Generalized Total Variation Regularization
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59129
ANO7 expression in the prostate modulates mitochondrial function and lipid metabolism
Published 2025-02-01“…Methods We performed RNA-sequencing (RNA-seq) on RWPE1 cells engineered to express ANO7 protein, alongside the analysis of a single-cell RNA-sequencing (scRNA-seq) dataset and RNA-seq from prostate tissues. …”
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59130
Split-Cre-mediated GFP expression as a permanent marker for flagellar fusion of Trypanosoma brucei in its tsetse fly host
Published 2025-02-01“…We have developed a split-Cre-Lox system to permanently label trypanosomes that undergo flagellar fusion. Specifically, we engineered trypanosomes to contain a GFP gene flanked by Lox sites in the reverse orientation to the promoter. …”
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59131
Low dose DNA methyltransferase inhibitors potentiate PARP inhibitors in homologous recombination repair deficient tumors
Published 2025-01-01“…In animal studies, our BRCA-engineered hypomorphs and several independent PDX models with clinically relevant BRCA mutations were acutely more vulnerable to this drug combination. …”
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59132
Novel and potent MICA/B antibody is therapeutically effective in KRAS LKB1 mutant lung cancer models
Published 2025-01-01“…Cell surface expression of MICA/B in NSCLC cell lines was determined through flow cytometry while ligand shedding in both patient blood and cell lines was determined through ELISA. We engineered an antibody-dependent cellular cytotoxicity (ADCC) enhanced MICA/B monoclonal antibody, AHA-1031, which prevents ligand shedding without interfering with binding to natural killer group 2D while targeting cancer cells via superior ADCC. …”
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59133
Development and utilization of Treponema pallidum expressing green fluorescent protein to study spirochete-host interactions and antibody-mediated clearance: expanding the toolbox...
Published 2025-01-01“…In this study, we took advantage of recent advances in in vitro cultivation and genetic manipulation of syphilis spirochetes to engineer a TPA strain that constitutively expresses green fluorescent protein (GFP). …”
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59134
System-Technology Co-Optimization for Dense Edge Architectures Using 3-D Integration and Nonvolatile Memory
Published 2024-01-01“…The framework is built on three engines that provide the physical design characterization, dataflow mapping optimizer, and system efficiency predictor. …”
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59135
Apical transportation of nickel titianium reciprocating instruments. An in vitro study
Published 2024-04-01“…The blocks in Group C were prepared with an Elements Adaptive engine set to the dedicated program for TF Adaptive. …”
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59136
Types of Complications and Associated Factors in Patients Undergoing Permanent Cardiac Pacemaker Implantation: A Systematic Review
Published 2025-01-01“…The database used was PubMed, CINAHL: Medline Ultimate, ScienceDirect, Scopus, and search engines: Google Scholar. Articles with observational designs and RCTs in English were included without limitation of publication year.Results: This review analyzed 15 articles. …”
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59137
The availability and functionality of medical equipment and the barriers to their use at comprehensive specialized hospitals in the Amhara region, Ethiopia
Published 2025-01-01“…The present study also indicated that 75% of the surveyed facility's biomedical engineers did not receive on-the-job training regularly. …”
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59138
TC2N maintains stem cell-like characteristics to accelerate lung carcinogenesis by blockade of dual specificity protein phosphatase 3
Published 2025-01-01“…Beyond that, its precise function in tumorigenesis is not fully understood. Methods TC2N-engineered mice model was used to assess the effect of TC2N knockout on normal lung and urethane-induced carcinogenesis. …”
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59139
FoxA1 knockdown promotes BMSC osteogenesis in part by activating the ERK1/2 signaling pathway and preventing ovariectomy-induced bone loss
Published 2025-02-01“…Transplanting genetically engineered MSCs has been acknowledged as a highly promising therapy for osteoporosis. …”
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59140
Prevalence of depression among medical students in Africa: Systematic review and meta-analysis.
Published 2024-01-01“…<h4>Method</h4>Original articles about the prevalence of depression among African medical students were searched through known and international databases (PubMed, Scopus, Web of Science, and Cochran Library) and search engines (Google and Google Scholar). Data were extracted using a standard data extraction checklist that was developed according to Joanna Briggs Institute (JBI). …”
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