GBS-DP: a bioinformatics pipeline for processing data coming from genotyping by sequencing by A. Y. Pronozin, E. A. Salina, D. A. Afonnikov

“…The pipeline is implemented using the Snakemake workflow engine. This implementation allows fully automating the process of calculation and installation of the necessary software packages. …”
Get full text

CRISPR/Cas9-editing of PRNP in Alpine goats by Aurélie Allais-Bonnet, Christophe Richard, Marjolaine André, Valérie Gelin, Marie-Christine Deloche, Aurore Lamadon, Gwendoline Morin, Béatrice Mandon-Pépin, Eugénie Canon, Dominique Thépot, Johann Laubier, Katayoun Moazami-Goudarzi, Ludivine Laffont, Olivier Dubois, Thierry Fassier, Patrice Congar, Olivier Lasserre, Tiphaine Aguirre-Lavin, Jean-Luc Vilotte, Eric Pailhoux

“…The aim of this work was to engineer Alpine goats carrying knockout (KO) alleles of PRNP, the PrPc-encoding gene, using CRISPR/Cas9-ribonucleoproteins and single-stranded donor oligonucleotides. …”
Get full text

An efficient smart phone application for wheat crop diseases detection using advanced machine learning. by Awais Amir Niaz, Rehan Ashraf, Toqeer Mahmood, C M Nadeem Faisal, Muhammad Mobeen Abid

“…This study proposes an efficient application for wheat crop disease diagnosis, adaptable for both mobile devices and computer systems as the primary decision-making engine. The application utilizes sophisticated machine learning techniques, including Decision Tree (DT), Random Forest (RF), Support Vector Machine (SVM), and AdaBoost, combined with feature extraction methods such as Count Vectorization (CV) and Term Frequency-Inverse Document Frequency (TF-IDF). …”
Get full text

Ethnotherapeutic Uses and Phytochemical Composition of Physalis peruviana L.: An Overview by Félicien Mushagalusa Kasali, Jonans Tusiimire, Justin Ntokamunda Kadima, Casim Umba Tolo, Anke Weisheit, Amon Ganafa Agaba

“…Data were collected from Google Scholar, PubMed/Medline, SciFinder, Science Direct, Scopus, the Wiley Online Library, Web of Science, and any other helpful search engine using Physalis peruviana as the primary keyword. …”
Get full text

Numerical nonlinear analysis of RC beams with un-strengthened and CFRP-strengthened opening drilled under service loads within shear zones by Magdy Khalaf, Louay Aboul-Nour, Mahmoud Khater, Marwa Ibrahim

“…Some important conclusions and recommendations for designer and executive engineers are stated.…”
Get full text

The impact of social networking addiction on the academic achievement of university students globally: A meta-analysis by Nader Salari, Hosna Zarei, Shabnam Rasoulpoor, Hooman Ghasemi, Amin Hosseinian-Far, Masoud Mohammadi

“…Methods: In this systematic review and meta-analysis, the keywords of Social Network, Addiction, Academic Performance, and University Students, and their suitable combinations were searched within PubMed, Web of science, JISC Library Hub Discover, the Library of congress, and the Google scholar search engine with no lower time limit and until February 2022. …”
Get full text

Higher Education and the Challenges of Network Society: Philosophical Themes by B. V. Markov

“…It was implemented in Russia as a two-tiered system, although the society still needed specialists and engineers rather than bachelors and masters. The restructuring of the educational process to comply with international standards then led to the necessity of economic reform. …”
Get full text

Dealing with post-excavation data: the Omeka S TiMMA web-database by Rueff, Bastien

“…The TiMMA project also faces the limitations of Omeka S, such as the lack of efficiency of the search engine, which makes the use of web-semantic vocabularies difficult, a few bugs, and the absence of convenient functionalities in archaeological projects (e.g. the automatic creation of primary keys, a statistic dashboard, cells’ automatic filling). …”
Get full text

Community Perception on the Effect of Cultural Livelihoods on the Environment in Kogi State, Nigeria by G. O. Chukwurah, N. M. Aguome, M. O. Isimah, E. C. Enoguanbhor, N. E. Obi-Aso, N. U. Azani and O. C. Nnamani

“…Secondary and primary data were employed, which include archives and internet search engines. Using a 4-stage sampling procedure, data were collected from a 120-person sample through an interview, field observation, a focus group discussion, and a questionnaire. …”
Get full text

Easy, fast and reproducible Stochastic Cellular Automata with chouca by Génin, Alexandre, Dupont, Guillaume, Valencia, Daniel, Zucconi, Mauro, Ávila-Thieme, M. Isidora, Navarrete, Sergio A., Wieters, Evie A.

“…Besides providing better reproducibility and accessibility, a fast engine for SCA unlocks novel, computationally intensive statistical approaches, such as simulation-based inference of ecological interactions from field data, which represents by itself an important avenue for research. …”
Get full text

The Role of Policies Governing Urban Land Development in Sari by masoumeh amiribesheli, Hossein Mojtaba zadeh Khanghahi

“…Cities play an important role in the economic growth of each country, with nearly 60 percent of the GDP of developing countries being produced in cities. They are the main engines of the growth of each country's national economy. …”
Get full text

Combinatorial immunotherapy with anti-ROR1 CAR NK cells and an IL-21 secreting oncolytic virus against neuroblastoma by Yaya Chu, Meijuan Tian, Uksha Saini, Jessica Ayala-Cuesta, Kayleigh Klose, Alyssa S. Mendelowitz, Keira Foley, Mehmet F. Ozkaynak, Wen Luo, Timothy P. Cripe, Dean A. Lee, Kevin A. Cassady, Mitchell S. Cairo

“…In the current study, we successfully engineered ex-vivo-expanded NK cells to express a chimeric antigen receptor (CAR) against ROR1 using mRNA electroporation and investigated the efficacy of anti-ROR1-CAR-NK cells combined with C021 in targeting ROR1+ NB. …”
Get full text

Oncolytic vaccinia virus armed with anti-CD47 nanobody elicit potent antitumor effects on multiple tumor models via enhancing innate and adoptive immunity by Jie Chen, Liu Yang, Mengyuan Li, Qian Ye, Shibing Wang, Zengpeng Li, Wenbin Qian

“…However, this therapeutic approach is often hampered by on-target side effects, physical barriers, and immunosuppressive tumor microenvironment (TME).Methods To improve therapeutic efficacy while minimizing toxicities, we engineered an oncolytic vaccinia virus (OVV) encoding an anti-CD47 nanobody (OVV-αCD47nb). …”
Get full text

Development of RT-PCR Assays for Simple Detection and Identification of Sabin Virus Contaminants in the Novel Oral Poliovirus Vaccines by Olga Singh, Hasmik Manukyan, Erman Tritama, Shwu-Maan Lee, Jerry P. Weir, Majid Laassri

“…A novel OPV2 vaccine (nOPV2) with enhanced genetic stability was developed recently; type 1 and type 3 nOPV strains were engineered using the nOPV2 genome as a backbone by replacing the capsid precursor polyprotein (P1) with that of Sabin strains type 1 and type 3, respectively. …”
Get full text

Digital multiple health behaviour change intervention targeting online help seekers: protocol for the COACH randomised factorial trial by Hanna Henriksson, Pontus Henriksson, Marie Löf, Preben Bendtsen, Marcus Bendtsen, Katarina Åsberg, Oskar Lundgren, Jenny Blomqvist

“…The study population will be those seeking help online, recruited through search engines, social media and lifestyle-related websites. …”
Get full text

Utilizing MRAMs With Low Resistance and Limited Dynamic Range for Efficient MAC Accelerator by Sateesh, Kaustubh Chakarwar, Shubham Sahay

“…The recent advancements in data mining, machine learning algorithms and cognitive systems have necessitated the development of neuromorphic processing engines which may enable resource and computationally intensive applications on the internet-of-Things (IoT) edge devices with unprecedented energy efficiency. …”
Get full text

The importance of stem cells in the treatment of type 1 diabetes, type 2 diabetes and diabetes complications by Monika Kamińska, Maria Jasiewicz, Magdalena Miernik-Skrzypczak, Aleksandra Spyra, Marta Malicka, Natalia Dąbrowska, Aleksandra Kozioł, Katarzyna Moczyróg

“…They were found using the PubMed search engine, and the time frame of these publications covered the last 20 years. …”
Get full text

Electricity Generation from Cow Dung Biogas by J. Akpojaro, G. Ofualagba, M.A. Akpojaro

“…We successfully modified the internal combustion engine, which works smoothly without any sign of audible knocking during the entire experimentation. …”
Get full text

ACTION: Augmentation and computation toolbox for brain network analysis with functional MRI by Yuqi Fang, Junhao Zhang, Linmin Wang, Qianqian Wang, Mingxia Liu

“…Moreover, current studies usually focus on analyzing fMRI using conventional machine learning models that rely on human-engineered fMRI features, without investigating deep learning models that can automatically learn data-driven fMRI representations. …”
Get full text

Digital games and virtual reality applications in child abuse: A scoping review and conceptual framework. by Afsoon Asadzadeh, Hassan Shahrokhi, Behzad Shalchi, Zhila Khamnian, Peyman Rezaei-Hachesu

“…The framework is developed in two stages: (1) a scoping review to gather digital games and VR applications for child abuse issues through the search in PubMed, Ovid (APA PsycInfo), Scopus, Web of Science, ProQuest, Institute of Electrical and Electronics Engineers (IEEE), Cochrane Database of Systematic Reviews, and grey literature and (2) developing a conceptual framework based on the review results and validating it by 12 experts. …”
Get full text