Template switching during DNA replication is a prevalent source of adaptive gene amplification by Julie N Chuong, Nadav Ben Nun, Ina Suresh, Julia Cano Matthews, Titir De, Grace Avecilla, Farah Abdul-Rahman, Nathan Brandt, Yoav Ram, David Gresham

“…To test the role of these genomic elements on CNV-mediated adaptive evolution, we evolved engineered strains lacking either the adjacent LTRs, ARS, or all elements in glutamine-limited chemostats. …”
Get full text

<i>Agrobacterium rhizogenes</i>-Mediated Hairy Root Transformation in <i>Rosa</i> by Jun Lu, Yuwen Huang, Yuhan Guo, Chunguo Fan, Guozhen Yuan, Rui Zhou, Jingjing Sun, Mengjuan Bai, Kun Wang, Jinyi Liu, Changquan Wang

“…The rapid and efficient transformation system developed here will enable efforts to investigate gene function in roses and engineer improved rose varieties. Refining the transformation protocol to work under aseptic and non-aseptic conditions will allow researchers to use this system efficiently and broadly.…”
Get full text

Minimum effort adaptation of automatic speech recognition system in air traffic management by Mrinmoy Bhattacharjee, Petr Motlicek, Srikanth Madikeri, Hartmut Helmke, Oliver Ohneiser, Matthias Kleinert, Heiko Ehr

“…However, typically, a “universal” ASR engine capable of reliably recognizing a core dictionary of several hundreds of frequently used words suffices for ATM applications. …”
Get full text

Geopolymers in nuclear waste storage and immobilization: mechanisms, applications, and challenges by M. Houhou, N. Leklou, H. Ranaivomanana, JD. Penot, S. de Barros

“…Cementitious materials such as ordinary Portland cement (OPC) and other materials are commonly employed as engineered barriers for the long-term containment of nuclear waste in both surface and underground geological repositories. …”
Get full text

The principles of tactical formation identification in association football (soccer) — a survey by Hadi Sotudeh

“…Preprocessing includes match segments and normalized locations followed by data representation using various options, such as average locations, hand-engineered features, and graphs for the team-level and relative locations, distributions, and images for the position-level approaches. …”
Get full text

Health Care System in Sudan: Review and Analysis of Strength, Weakness, Opportunity, and Threats (SWOT Analysis) by Ebrahim Mohammed Abdullah Ebrahim, Luam Ghebrehiwot, Tasneem Abdalgfar, Muhammad Hanafiah Juni

“…Materials and Methods: The search was done from two electronic databases: MEDLINE/Pubmed and from public search engines: Google Scholar and Google with key Search words used mainly as “Healthcare system in Sudan “. …”
Get full text

Reverse Design of Cycloid Tooth Profile Without Trapped Oil and Implementation Measures of Low Flow Ripple for Gear Pump by Yuncai Xia, Haibin Hao, Yin Mao

“…All results show that the reverse design method of cycloidal tooth profile is simple and accurate，and can be directly used by general engineers； the contact ratio of a single gear pair is 1 to ensure that gear pump has no trapped oil phenomenon； the axial dislocation assembly of double gear pairs with special angle of π divided by tooth number is easy to be realized，and axial comprehensive contact ratio is 2 to ensure transmission stability of cycloidal gear pair； minimum number of teeth is 6 and there is no root cutting phenomenon； compared with single gear pair，an about 75% ripple improvement rate is seen in double gear pair and the optimal tooth profile parameters based on the minimization of ripple factor can be directly applied to the production practice，etc. …”
Get full text

Involvement of the intracellular β-glucosidase BGL1B from Aspergillus niger in the regulation of lignocellulose-degrading enzymes’ synthesis by Zhen Zhang, Hua Li, Feiyu Dong, Hui Lin, Yanan Li, Kun Cheng, Hongge Chen

“…Also, it provides a strategy to create an engineered strain with high production of lignocellulose-degrading enzymes.…”
Get full text

Environmental threats and risks to protected areas in the context of war (case study of Molochnyi Lyman) by L. A. Horoshkovа, Y. D. Korniichuk

“…System analysis, remote sensing data were used, specifically satellite images from Landsat 5, Landsat 8, Sentinel-2, and the software tool Google Earth Engine. Results. The biodiversity of Molochnyi Lyman is characterized and the impact of the salinity level on its biodiversity is analyzed. …”
Get full text

Science-based communication and education needed to improve forest carbon science, policy, and management outcomes by Chad C Papa, Kylie Clay, Lauren T Cooper, Scott C Stark

“…Because forests stand to play a significant role in reaching net-zero emission targets, politicians and policymakers must act decisively to engineer a rapid paradigm shift that maintains forests’ resilience and adaptive capacity. …”
Get full text

Modified CD15/CD16-CLL1 inhibitory CAR-T cells for mitigating granulocytopenia toxicities in the treatment of acute myeloid leukemia by Rui Zhang, Yifan Zhao, Xiao Chai, Yingshuai Wang, Mohan Zhao, Shujing Guo, Yu Zhang, Mingfeng Zhao

“…In conclusion, we have successfully engineered innovative CD16-CLL1 iCAR-T cells, which preserves the cytotoxicity against tumor cells while preventing elimination of neutrophils, thereby significantly reducing the incidence of granulocytopenia during CAR-T therapy. …”
Get full text

Pleiotropic effects of mutant huntingtin on retinopathy in two mouse models of Huntington's disease by Hui Xu, Anakha Ajayan, Ralf Langen, Jeannie Chen

“…We investigated whether these defects extend to the zQ175KI mouse model which is thought to be more representative of the human condition because it was engineered to contain the extended CAG repeat within the endogenous HTT locus. …”
Get full text

Reducing Emissions Using Artificial Intelligence in the Energy Sector: A Scoping Review by Janne Alatalo, Eppu Heilimo, Mika Rantonen, Olli Väänänen, Tuomo Sipola

“…This paper follows the PRISMA-ScR guidelines in reporting the findings. The academic search engine Google Scholar was utilized to find papers that met the review criteria. …”
Get full text

Binding and bonding of commercialization and collaboration by KPIs: An integrated approach for sustainable agriculture research performance management by Prabath Chaminda Abeysiriwardana, Udith Krishantha Jayasinghe-Mudalige

“…Results suggest that commercialization was not optimized beyond a threshold value of innovative activity from a developing country perspective and that collaborations were underestimated in propelling innovation engines. Similarities were observed in their insights on commercialization and collaboration, highlighting the necessity of integrating those measurements for a synergetic effect. …”
Get full text

Experimental and Modeling Study of Soil Water Retention Curves of Compacted Bentonite considering Salt Solution Effects by Yong He, Ke-neng Zhang, Dong-yu Wu

“…Due to its low hydraulic conductivity, high swelling capacity, and good adsorption properties, the Gaomiaozi (GMZ) bentonite has been selected as potential buffer/backfill materials for construction of engineered barriers in the deep geological repository for disposal of high-level nuclear waste (HLW) in China. …”
Get full text

‘Stupid Girls’ vs. ‘Real Men’: Identity Construction and Social Media Polarization over Revenge Porn by Marta Sánchez Cócera

“…The paper adopts a Corpus-Assisted Discourse Studies (CADS) approach (Partington et al. 2013) and uses Sketch Engine to analyze the corpus. Additionally, a more detailed analysis of evaluative resources and linguistic patterns is carried out. …”
Get full text

Modelling and Analysis of Autonomous Airport Surface Movement Operations based on Multi-Agent Planning by Malte von der Burg, Alexei Sharpanskykh

“…The model incorporates the decisive processes and elements of airport surface movement operations such as pushback, engine-start, inbound and outbound holding, compliance to CTOT-slots, and wake turbulence separation for takeoffs. …”
Get full text

Development of New Models for the Estimation of Hourly Components of Solar Radiation: Tests, Comparisons, and Application for the Generation of a Solar Database in Morocco by Mohammed Benchrifa, Rachid Tadili, Ahmed Idrissi, Hajar Essalhi, Abdellah Mechaqrane

“…Thus, the data bank that we have realized will fill the gap of the hourly solar data and will meet the needs of engineers, installers of solar systems, and researchers who often need an extensive database.…”
Get full text

A methodology for assessing and managing university awareness in the digital environment: A case of Russia’s federal districts by Aliya A. Gataullina, Alina F. Garyaeva, Alina A. Zyabbarova

“…The article develops a methodology for assessing university awareness in the digital environment and determining its reputation through analysing the frequency of web queries in the Yandex search engine. The entrepreneurial university concept constitutes the theoretical framework of the study. …”
Get full text

Comparison of three recent discrete stochastic inversion methods and influence of the prior choice by Juda, Przemysław, Straubhaar, Julien, Renard, Philippe

“…PoPEx and ESDMA are used with Multiple-point statistics (MPS) as geostatistical engines, and DREAM-ZS is used with a Wasserstein generative adversarial network (WGAN). …”
Get full text