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58481
Metal‐based nanomaterials and nanocomposites as promising frontier in cancer chemotherapy
Published 2023-04-01“…Nanomaterials (NMs) have unique properties that make them useful for various diagnostic and therapeutic purposes in cancer research. NMs can be engineered to target cancer cells for early detection and can deliver drugs directly to cancer cells, reducing side effects and improving treatment efficacy. …”
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58482
Widespread Striatal Delivery of GDNF from Encapsulated Cells Prevents the Anatomical and Functional Consequences of Excitotoxicity
Published 2019-01-01“…Human ARPE-19 cells engineered to secrete high levels of the glial cell line-derived neurotrophic factor (GDNF) were encapsulated into hollow fiber membranes. …”
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58483
Neologismos fraseológicos en el español hablado en Argentina: los procedimientos de creación
Published 2020-11-01“…Aplicamos, además, el criterio de neologicidad de exclusión lexicográfica y comprobamos su uso en la variante argentina del corpus periodístico esAmTenTen11 (español de América) aplicando la herramienta Sketch Engine.…”
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58484
Intracerebroventricular administration of a modified hexosaminidase ameliorates late-stage neurodegeneration in a GM2 mouse model.
Published 2025-01-01“…Here, we assess the effect of recombinant HexA and HexD3, a newly engineered mimetic of HexA optimized for the treatment of Tay-Sachs disease and Sandhoff disease. …”
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58485
Thermoelectric properties of a quantum dot attached to normal metal and topological superconductor
Published 2025-01-01“…We also consider the system out of equilibrium working as a heat engine. The output power and the corresponding efficiency are presented. …”
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58486
German-Danish or Danish-German? – A study of nationality adjectives in hyphenated compounds
Published 2024-10-01“…The study’s premise is that linguistic fixity and conventionality reflect fixed “Denkmuster” (‘patterns of thought’, Stein & Stumpf 2019, 193), also in collocations. The two Sketch Engine corpora, daTenTen20 and deTenTen18, serve as the empirical basis for the comparison. …”
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58487
Strains, Mechanism, and Perspective: Salmonella-Based Cancer Therapy
Published 2016-01-01“…One of these Salmonella models is our Salmonella enterica serovar Typhimurium LT2 derived strain CRC2631, engineered to minimize toxicity but maximize tumor-targeting and destruction effects. …”
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58488
Evaluation of Machine Learning Models for Mapping Food Crops using Sentinel-2A Imagery in West Java, Indonesia
Published 2024-01-01“…The aim of this research is to evaluate machine learning models in mapping and calculating the area of food crops (rice) in West Java Province, Indonesia. Google Earth Engine is used in this study as a big data cloud computing platform for remote sensing. …”
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58489
Strategies to enhance THz harmonic generation combining multilayered, gated, and metamaterial-based architectures
Published 2025-01-01“…These findings underscore the potential of engineered graphene-based structures in advancing THz frequency conversion technologies for signal processing and wireless communication applications.…”
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58490
Cross-Talk between PPARs and the Partners of RXR: A Molecular Perspective
Published 2009-01-01“…Novel tools, such as engineered nuclear receptors with altered dimerization properties, are currently being developed. …”
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58491
RESEARCH ON CREEP TEST AND CONSTITUTIVE MODEL COMPARISON OF COMРАСTED GRAPHITE CAST IRON UNDER WIDE TEMPERATURE AND STRESS RANGE
Published 2024-02-01“…As the power density of an engine increases, so does the temperature and stress that the cylinder head is subjected to during operation. …”
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58492
ANALYSIS OF POROSITE-NEUTRON (NPHI) LOGGING DATA FROM THE KINKASI FIELD: THE CASE OF THE G UP, F AND E HORIZONS OF THE CENOMANIAN RESERVOIR (D.R. CONGO COASTAL BASIN)
Published 2024-11-01“…As well as highlighting the importance of modelling the petrophysical parameters of a reservoir in the development of an oil field, this subject provides assistance to the Production Engineer, insofar as it makes it possible to visualise, from the desktop with some software such as Microsoft Excel 2010 for the calculation of certain data with a view to representing them in the form of tables and graphs, the Geographic Information System (ArcGis 10.3) for representing the study area and drawing up maps of the spatial distribution of porosity-neutron horizons, areas of interest that could be the subject of in-depth studies ((location of new wells).…”
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58493
The Reporter System for GPCR Assay with the Fission Yeast Schizosaccharomyces pombe
Published 2012-01-01“…Yeasts are often utilized as a host for heterologous GPCR assay. We engineered the intense reporter plasmids for fission yeast to produce green fluorescent protein (GFP) through its endogenous GPCR pathway. …”
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58494
Bacteria as Precision Tools for Cancer Therapy
Published 2025-01-01“…Two recent studies in MBT highlight the promise of using Salmonella typhimurium and Escherichia coli as vectors in novel cancer treatments. Engineered S. typhimurium strains can generate adjuvant flagellin‐antigen complexes that function as in situ vaccines, hence increasing the immunogenic responses within tumour environment. …”
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58495
Emerging roles of extracellular vesicles in oral and maxillofacial areas
Published 2025-02-01“…This paper reviews the published data on extracellular vesicles derived from cells, body fluids, and tissues in oral and maxillofacial regions, summarizes the latest advances in extracellular vesicles from extensive sources, and concludes with a focus on the current research progress and application prospects of engineered exosomes in oral science.…”
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58496
State-of-the-Art of CSR Design for Novel Applications Trend
Published 2025-01-01“…Thus, rather than focusing on a specific aspect of CSRs, this article provides a comprehensive overview of the topic, offering practical insights for engineers.…”
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58497
Artificial Intelligence in Oncology
Published 2024-12-01“…The search for scientific publications was carried out through the following web search engines: PubMed, PMC, Web of Science, Scopus, Embase and Ebsco. …”
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58498
Autophagic flux modulates tumor heterogeneity and lineage plasticity in SCLC
Published 2025-01-01“…Autophagy, a conserved cellular process, is implicated in many cancers, but its role in SCLC remains unclear.MethodsUsing a genetically engineered mouse model (Rb1fl/fl; Trp53fl/fl; GFP-LC3-RFP-LC3△G), we tracked autophagic flux in vivo to investigate its effects on SCLC biology. …”
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58499
Prospects of China-EAEU Cooperation on Digital Economy
Published 2019-11-01“…The article shows that the digital economy as a result of the genesis of the information revolutions is a new key engine for sustainable economic development, improvement of productivity, reconfiguration of the international division of labor and the deepening of globalization processes and the emergence of new markets and industries in the world in the post-crisis period. …”
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58500
The analysis of the influence of the turbulence model selection on the parameters of interaction of a supersonic jet with an obstacle
Published 2024-10-01“…Due to the intense loading of the elements of launch structures when exposed to rocket engine jets, it is obvious that it is necessary to determine the gas-dynamic, thermal and other loads that occur during the launch of the launch vehicle. …”
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