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A PCR-independent, annealing-free cloning method for the insertion of short DNA fragments
Published 2024-11-01Get full text
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Improvement in XIa Selectivity of Snake Venom Peptide Analogue BF9-N17K Using P2′ Amino Acid Replacements
Published 2025-01-01“…In addition, according to the molecular diversity and sequence conservation, a common motif GR/PCR/KA/SXIP-XYGGC is proposed in the XIa-inhibitory Kunitz-type peptides, which might provide a new clue for further peptide engineering. In conclusion, through P2′ amino acid classification scanning with the snake venom Kunitz-type peptide scaffold, a new potent and selective XIa inhibitor, BF9-N17K-L19D, was discovered, which provides a new XIa-targeting lead drug template for the treatment of thrombotic-related diseases.…”
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Transferrin Disassociates TCR from CD3 Signaling Apparatus to Promote Metastasis
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γ-亚麻酸对α-亚麻酸转化为DHA的影响 Effect of γ-linolenic acid on the conversion of α-linolenic acid to DHA
Published 2025-01-01Get full text
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Sex disparity in the association between alcohol consumption and sarcopenia: a population-based study
Published 2025-02-01Get full text
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homeRNA self-blood collection enables high-frequency temporal profiling of presymptomatic host immune kinetics to respiratory viral infection: a prospective cohort studyResearch in...
Published 2025-02-01“…Funding: This study was funded by R35GM128648 to ABT for in-lab developments of homeRNA and data analysis, a Packard Fellowship for Science and Engineering from the David and Lucile Packard Foundation to ABT for the study execution, sample collection, and analysis, and R01AI153087 to AW for data analysis.…”
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Educide amid conflict: the struggle of the Palestinian education system
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