Showing 1,741 - 1,760 results of 59,424 for search '"Engineer"', query time: 0.12s Refine Results
  1. 1741

    A Method and Engineering Practice for a Fully Mechanized Caving Coalface to Rapidly Pass Through a Large Fault by Wei Zhang, Feili Yang, Jingyu Chang, Shengxun Zhao, Bin Xu, Jinyong Xiang

    Published 2025-01-01
    “…The main implementation steps of the method include designing the layout parameters of the pre-driven roadways, determining the width for rock pillars between the adjacent pre-driven roadways, construction of pre-driven roadways by smooth wall blasting, and controlling the surrounding rock deformation of the pre-driven roadways. The results of engineering practice show that it took only 23 days for this coalface to pass through fault F<sub>6</sub>, about one month shorter than the time required by traditional methods (e.g., proactively taking a detour). …”
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    Overcoming CD226-related immune evasion in acute myeloid leukemia with CD38 CAR-engineered NK cells by Luciana Melo Garcia, Achintyan Gangadharan, Pinaki Banerjee, Ye Li, Andy G.X. Zeng, Hind Rafei, Paul Lin, Bijender Kumar, Sunil Acharya, May Daher, Luis Muniz-Feliciano, Gary M. Deyter, Gabriel Dominguez, Jeong Min Park, Francia Reyes Silva, Ana Karen Nunez Cortes, Rafet Basar, Nadima Uprety, Mayra Shanley, Mecit Kaplan, Enli Liu, Elizabeth J. Shpall, Katayoun Rezvani

    Published 2025-01-01
    “…CRISPR-Cas9 deletion of CD226 led to reduced LFA-1 recruitment, poor synapse formation, and decreased NK cell anti-leukemic activity. Engineering NK cells to express a chimeric antigen receptor targeting the AML antigen CD38 (CAR38) could overcome the need for CD226 to establish strong immune synapses. …”
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  4. 1744

    Carbonic anhydrase 2-derived drug-responsive domain regulates membrane-bound cytokine expression and function in engineered T cells by Mara C. Inniss, Sean G. Smith, Dan Jun Li, Benjamin Primack, Dexue Sun, Grace Y. Olinger, Kerri-Lynn Sheahan, Theresa Ross, Meghan Langley, Violet Young, Andres Alvarado, Shabnam Davoodi, Jiefei Geng, Michael Schebesta, Michelle L. Ols, Jeremy Tchaicha, Jan ter Meulen, Dhruv K. Sethi

    Published 2025-01-01
    “…We develop conditional degrons using library-based screening of mutants and show characterization of one DRD using crystallography and molecular dynamics (MD) simulations. Using protein-engineering solutions to increase the valency of DRDs fused to the cargo we have developed “modulation hubs” and show tight regulation of membrane-bound cytokines IL2, IL12, IL15, IL21, IL23, and IFNα in genetically engineered T cells. …”
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  5. 1745

    A case study in statistical software development for advanced evidence synthesis: the combined value of analysts and research software engineers by Naomi Bradbury, Tom Morris, Clareece Nevill, Janion Nevill, Ryan Field, Suzanne Freeman, Nicola Cooper, Alex Sutton

    Published 2025-01-01
    “…Key challenges We discuss how we have addressed challenges to research software development such as responding to feedback from our real-world users to improve the CRSU apps, the implementation of software engineering principles into our app development process and gaining recognition for non-traditional research work within the academic environment. …”
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    Industry Based Adaptive Educational Programs by M. G. Ganchenkova, O. V. Boyko

    Published 2019-12-01
    Subjects: “…engineering education…”
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    Effect of Multiple Injection Strategy Under High Ammonia Ratio on Combustion and Emissions of Liquid Ammonia/Diesel Dual DI Engine by Zhenbin Chen, Yudong Wan, Omar I. Awad, Zhiqiang Pan

    Published 2025-01-01
    “…Ammonia diesel dual fuel (ADDF) engine is one of the effective ways to reduce carbon emissions. …”
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  18. 1758

    THE EFFECT OF FAMILY PARENTING ON EARLY MARRIAGE KNOWLEDGE IN ADOLESCENTS IN SENIOR HIGH SCHOOL 1 PLUS COMPUTER NETWORK ENGINEERING IN 2021 by Ahmad Zubairi, Nova Seftiana

    Published 2021-10-01
    “…Results: From the results of bivariate analysis using the chi square test, the p-value of 0.038 (<0. 05) can be concluded so that it can be concluded that there is a relationship between family parenting patterns and perceptions of early marriage in adolescents in Senior High School 1 Plus Computer Nerwork Engineering in 2021. Conclusion: The results of the respondents were 50 female students and 30 male students. …”
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  19. 1759

    Ultra-low strain hysteresis in BaTiO3-based piezoelectric multilayer actuators via microstructural texture engineering by Yingchun Liu, Hongjun Zhang, Wenming Shi, Kai Li, Bin Yang, Wenwu Cao, Jiubin Tan

    Published 2025-03-01
    “…In this work, we adopted a synergistic strategy of crystallographic texturing and domain engineering in BaTiO3-based MLAs to enhance strains by improving piezoelectricity while simultaneously restraining the ultra-low hysteresis. …”
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