Assessment of efficacy and safety of imatinib as an adjunct host-targeted therapy for parasite clearance in chloroquine-resistant malaria: a prospective case control study by Fazeel Zubair Ahmed, Shaifulla P

“…Abstract Overview Chloroquine-resistant malaria poses a significant treatment challenge, especially in endemic areas. Host-targeted therapies, like tyrosine kinase inhibitors (TKIs) such as imatinib, have shown potential to improve malaria treatment outcomes by disrupting parasite egress from red blood cells. …”
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A Survey of Wild Indigenous <i>Cryptostylis ovata</i> Orchid Populations in Western Australia Reveals Spillover of Exotic Viruses by Stephen Wylie, Hua Li, Shu Hui Koh

“…<i>Cryptostylis ovata</i> is a terrestrial orchid endemic to southwestern Australia. The virus status of <i>C. ovata</i> has not been studied. …”
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Revision of the Oriental and Australasian diving beetle genus Sandracottus Sharp, 1882 (Coleoptera, Dytiscidae, Dytiscinae) by Lars Hendrich, Michel Brancucci

“…In total, three Oriental species, two of which also occur in the East Palaearctic, six Southeast Asian species, one species from New Guinea and the Moluccas, and one from Australia with an endemic subspecies in Central Australia (S. bakewellii guttatus) are recognised. …”
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A Pilot Seroprevalence Study Suggests Silent Zika virus Transmission in Bhopal Region of Central India by Shashwati Nema, Dipesh Kale, Romesh Jain, Ajay Halder, Manisha Shrivastava, Deepak Vaishnav, Ashvini Kumar Yadav, Divya Namdeo, Debasis Biswas

“…Materials and Methods: We screened a group of 75 febrile patients who had already tested negative for the locally endemic causes of fever like dengue, chikungunya, enteric fever, malaria, and scrub typhus and two groups of asymptomatic healthy individuals represented by blood donors (n = 75) and antenatal mothers (n = 75). …”
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Understanding reasons for delay in diagnosis of leprosy in Pakistan: A qualitative study. by Anil Fastenau, Maxwell Oliver Beresford, Matthew Willis, Sophie Cw Stuetzle, Fabian Schlumberger, Heleen Neeltje Willemijn Duighuisen

“…These domains were each viewed as consequent to the larger theme of 'low-endemicity'. Strong correlations between diagnostic delay and socioeconomic status, gender, geography and health system challenges, were also mentioned, and which intersected the three major themes.…”
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Woody Species Composition, Structure and Diversity of Trees-Based Agroforestry System in the Mid-Highlands, Konawe Regency, Southeast Sulawesi Province, Indonesia by Agus Setiawan, Nur Arafah

“…Plant species at the tree level 73%, herbaceous 10% and shrubs 17%, native endemic species 74%, and introduced 26%. A total of 77% of plant species were planted and 23% of species grew wild. …”
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Assessing the Roles of Molecular Markers of Antimalarial Drug Resistance and the Host Pharmacogenetics in Drug-Resistant Malaria by Peter Hodoameda, Nancy Odurowah Duah-Quashie, Neils Ben Quashie

“…Malaria caused by the Plasmodium parasites is a major public health concern in malaria-endemic regions with P. falciparum causing the most severe form of the disease. …”
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Floristic novelties in the context of interdisciplinary studies by N. P. Stepanyan-Gandilyan, R. A. Hovsepyan

“…Among the species, for which phytogeographic and floristic novelties were recorded, are crop wild relatives, endemics, and rare species, included in the IUCN list. …”
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Determination of risk factors and patient profile in human hydatidosis by Ahmet Korul, Mustafa Köse, Sezgin Yılmaz

“…<p> <b>Conclusion: </b>Hydatidosis is considered a very important public health problem with major socio-economic impacts in countries where it is particularly endemic. Patient profiles, demographics and risk factors are extensively presented in hydatidosis, an important parasitic zoonosis that threatens public health in Turkey in this study.…”
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Analysis of Five Earthy-Musty Odorants in Environmental Water by HS-SPME/GC-MS by Zhen Ding, Shifu Peng, Weiwen Xia, Hao Zheng, Xiaodong Chen, Lihong Yin

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Eilat virus isolated from Culex univittatus mosquitoes from the Namibian Zambezi Region influences in vitro superinfection with alpha- and flaviviruses in a virus-species-dependent... by Heiko D Guggemos, Anne Kopp, Katrin Voigt, Matthias Fendt, Selina L Graff, John K E Mfune, Christian Borgemeister, Sandra Junglen

“…In summary, EILV from the Namibian Zambezi region influences in vitro replication of endemic flavi- and alphaviruses.…”
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Defense strategy of industrial control worm based on SEIPQR model by Jie PAN, Lan YE, He ZHAO, Xinlei ZHANG

“…Computer viruses keep evolving with the development of society and progress of technologies, and they become more complex and hidden.The worm virus is the earliest computer virus, which has evolved to an industrial control worm virus and caused a great impact on the safety of the industrial system.Neither the single network isolation nor the patching immunity is unable to keep up with the spreading of the worm virus.The propagation mode and characteristics of the worm virus in the industrial control system were analyzed.Based on the related works of network isolation and patching, a defense strategy against the worm virus was proposed.This strategy was originated from the fundamental infectious disease model, and then a mathematics model (SEIPQR) was proposed to simulate the trend of worm virus propagation.The model included six situations: Susceptible, Exposed, Infected, Quarantine and Recovered.The state transition diagrams of the model was created, and the calculus equations were obtained from the state transition diagrams.Under the condition that the number of system equipment is fixed, the equations were transformed.The equations were solved by solving the basic regeneration number R0, and six equation expressions of the model ware analyzed when the number of exposed hosts and infected hosts is zero.According to the principle of the Routh-Hurwitz, the system is asymptotically stable when R₀＜1, and unstable if R₀＞1.Then the dynamic characteristics of the SEIPQR model under different patching probability, different isolation rate and different infection rate were compared by numerical simulation.Furthermore, the disease-free equilibrium point and endemic equilibrium point of the model were obtained.The simulation results showed that, when the whole system is infected with worm virus, timely patching the susceptible devices and isolating the network can effectively inhibit the spread of industrial control worm virus.…”
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Mathematical Modelling of Cholera Transmission incorporating Media Coverage. by Muhereza, Obed

“…The results of stability analysis showed that the disease free equilibrium was locally asymptotically stable when R< 1 while the endemic equilibrium was locally asymptotically stable when R> 1. p which is the efficacy of media coverage has an inverse relationship with the spread of the disease, such that whenever it is high, the disease spread reduces and when it is low, the disease spread increases. …”
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Prevalence of Trypanosoma congolense and Trypanosoma vivax in Lira District, Uganda by Aziz, Katabazi, Adamu, Almustapha Aliero, Simon Peter, Musinguzi

“…The return of displaced inhabitants led to the restocking of cattle from AAT endemic areas. It was thus important to estimate the burden of trypanosomiasis in the region. …”
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Optimal control analysis of Taenia saginata bovine cysticercosis and human taeniasis by Damian, Kajunguri, Joshua, A. Mwasunda, Jacob I, Irunde

“…The analysis shows that both the disease free equilibrium (DFE) and endemic equilibrium (EE) exist. To study the dynamics of the diseases, we derived the basic reproduction number R0 by next generation matrix method which shows whether the diseases die or persist in humans and cattle. …”
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A Comparison between the Effects of Glucantime, Topical Trichloroacetic Acid 50% plus Glucantime, and Fractional Carbon Dioxide Laser plus Glucantime on Cutaneous Leishmaniasis Les... by Fariba Jaffary, Mohammad Ali Nilforoushzadeh, Amirhossein Siadat, Elaheh Haftbaradaran, Nazli Ansari, Elham Ahmadi

“…Cutaneous leishmaniasis is an endemic disease in Iran. Pentavalent antimonial drugs have been the first line of therapy in cutaneous leishmaniasis for many years. …”
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Multispecies occupancy models unravel reduced colonization probabilities in plants from the unique Amazonian cangas by Rafael de Fraga, Luiz Gustavo Rodrigues Oliveira Santos, Valeria da Cunha Tavares, Leonardo Carreira Trevelin, Maurício Takashi Coutinho Watanabe, Leandro Maioli, Samir Rolim, Carolina da Silva Carvalho

“…Our results indicate that for some wide-ranging species, negative metapopulation equilibrium was restricted to mining plots, indicating sensitivity of these species to environmental changes caused by mining. For some endemic species, apparent population declines are more likely to be occurring due to natural causes than to the negative effects of mining.…”
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Economic impact of cholera in households in rural southern Malawi: a prospective study by Florian Marks, Wilm Quentin, Vittal Mogasale, Amber Hsiao, Enusa Ramani, Hye-Jin Seo, GiDeok Pak, Dan Vuntade, Maurice M’bang’ombe, Bagrey Ngwira

“…Few studies have estimated the cost of illness (COI) of cholera in Malawi, a cholera-endemic country. The present study estimated the COI of cholera in Nsanje, southern Malawi, as part of the Cholera Surveillance in Malawi (CSIMA) programme following a mass cholera vaccination campaign in 2015.Methods Patients ≥12 months of age who were recruited as part of CSIMA were invited to participate in the COI survey. …”
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SURVEILLANCE OF PARASITIC DISEASES IN BULGARIA by Rumen Harizanov, Violeta Yakimova, Mihaela Videnova, Ognyan Mikov, Aleksandra Ivanova, Eleonora Kaneva, Raina Borisova, Nina Tsvetkova, Iskra Rainova, Zornitca Traykova

“…In addition, parasitic infections imported from endemic tropical regions are recorded annually in the country. …”
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Evolutive radiological findings in a case of coccidioidal infection in an immunocompetent male: a case report by Paolo La Montanara, Annamaria Albergo, Loredana Capozzi, Roberto Castellana, Gerardo Cazzato, Carmela De Carlo, Sofia Denicolò, Antonella Netti, Mariacristina Poliseno, Enrica Maddalena Ranieri, Caterina Romano, Annalisa Rossiello, Stefania Stolfa, Alessandra Tripoli, Giuseppe Vella

“…Abstract Background Bone infections such as chronic fungal erosive osteomyelitis are uncommon forms of bone infection. The endemic dimorphic fungus Coccidioides impact generally immunocompromised patients. …”
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