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41
Integrating representation learning, permutation, and optimization to detect lineage-related gene expression patterns
Published 2025-01-01“…Furthermore, our method highlights differences in how gene expression memory is maintained through divisions in cancer and embryogenesis, thereby providing a tool for studying cell state memory through divisions across biological systems.…”
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42
Dynamic changes of extracellular vesicles during zebrafish organogenesis
Published 2025-02-01“…Despite its role as a well-established vertebrate model, little is known about EVs during zebrafish embryogenesis. This study investigates EVs during zebrafish embryogenesis, analysing size- and concentration-changes over time. …”
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43
Role of the Notch signaling pathway in porcine oocyte maturation
Published 2025-01-01“…In vitro maturation (IVM) and parthenogenetic activation of oocytes were employed to examine the effects of Notch signaling inhibition on meiotic progression and embryogenesis of COCs using RO4929097 (RO), an inhibitor of γ secretase. …”
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44
Multi-tissue characterization of the constitutive heterochromatin proteome in Drosophila identifies a link between satellite DNA organization and transposon repression.
Published 2025-01-01“…Using genetics, transcriptomics, and small RNA profiling, we show that flies lacking D1 during embryogenesis exhibit transposon expression and gonadal atrophy as adults. …”
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45
Longitudinal growth of the Saccharina kelp embryo depends on actin filaments that control the formation of a corset-like structure composed of alginate
Published 2025-01-01“…Abstract The initiation of embryogenesis in the kelp Saccharina latissima is accompanied by significant anisotropy in cell shape. …”
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46
Current Insights into Various In Vitro Dihaploidization Techniques Used in <i>Brassica</i> Oil Crops
Published 2025-01-01“…Different chemical compounds such as herbicides, brassinosteroids, and polyethylene glycol have an antimitotic effect and have been found to generate DH plants and improve microspore embryogenesis in <i>Brassica</i> species. Colchicine and trifluralin have proven to be efficient chromosome-doubling agents as well as important supplements that can increase the rate of embryogenesis. …”
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47
Automated Segmentation and Object Classification of CT Images: Application to In Vivo Molecular Imaging of Avian Embryos
Published 2013-01-01“…Background. Although chick embryogenesis has been studied extensively, there has been growing interest in the investigation of skeletogenesis. …”
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48
The Fourth Branchial Complex Anomaly: A Rare Clinical Entity
Published 2011-01-01“…Fourth branchial pouch anomalies are rare congenital disorders of the neck and are a consequence of abnormal development of the branchial apparatus during embryogenesis. Failure to appropriately recognize these anomalies may result in misdiagnosis, insufficient treatment, and continued recurrence. …”
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49
NATURAL MUTAGENESIS AS A POSSIBLE CAUSAL FACTOR FOR OCCURRENCE OF OBLIGATE EMBRYONIC DIAPAUSE IN MAMMALS (A HYPOTHESIS)
Published 2014-12-01“…Available data of cytogenetics, embryology, evolutionary morphology, and evolutionary ecology allow to believe that the obligatory stage of embryonic diapause might occur in single individuals with indifferent taxonomic groups in consequence of chromosome mutation caused by alteration in the environment and affected the expression of genes controlling the timing of embryogenesis.…”
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50
Dopamine receptors and key elements of the neurotrophins (BDNF, CDNF) expression patterns during critical periods of ontogenesis in the brain structures of mice with autism-like be...
Published 2024-07-01“…At the same time, the increase in p75NTR receptor gene expression observed on the 14th day of embryogenesis, crucial for hippocampus and frontal cortex development, may have direct relevance to the manifestation of early autism.…”
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51
STAT3-Inducible Mouse ESCs: A Model to Study the Role of STAT3 in ESC Maintenance and Lineage Differentiation
Published 2018-01-01“…However, there is still lack of direct evidence on STAT3 functions in ESCs and embryogenesis because constitutive STAT3 knockout (KO) mouse is embryonic lethal at E6.5–E7.5, prior to potential functional role in early development can be assessed. …”
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52
The Life of Embryon According to Thomas Aquinas
Published 2013-07-01“…He exposes in six stage of embryogenesis, which we can discover in his writings, the identity of the embryo in all process of his development. …”
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53
Targeting Signaling Pathways in Cancer Stem Cells for Cancer Treatment
Published 2017-01-01“…The Wnt, Hedgehog, and Notch pathways are inherent signaling pathways in normal embryogenesis, development, and hemostasis. However, dysfunctions of these pathways are evident in multiple tumor types and malignancies. …”
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54
Visualization of the Dynamics of Gene Expression in the Living Mouse
Published 2004-01-01“…Using this technology, we have determined the rate of gene induction and repression, the level of target gene activity in response to different doses of inducer, and the schedule of induction during early embryogenesis of both the endogenous and the experimentally manipulated programs of mammalian gene expression associated with the HD/Hdh locus. …”
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55
Gastrointestinal myofibroblasts: role in regulation of physiological activity and reparation of gastro-intestinal tract
Published 2010-06-01“…To analyze organ-specific features of gastrointestinal myofibroblasts, functional properties, role in embryogenesis and healing of ulcers of gastro-intestinal tract (GIT).Original positions. …”
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56
A Bird’s-Eye Overview of Leptin and Female Reproduction —with Mammalian Comparisons
Published 2025-02-01“…Leptin, a key regulator of reproductive physiology, influences various processes in vertebrates, including oocyte proliferation, embryogenesis, the onset of puberty, ovarian function, and follicle development. …”
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57
The Mitochondrial Disulfide Relay System: Roles in Oxidative Protein Folding and Beyond
Published 2013-01-01“…We proceed by discussing recently described functions of Mia40 in the hypoxia response and of ALR in influencing mitochondrial morphology and its importance for tissue development and embryogenesis. We also include a discussion of the still mysterious function of Erv1/ALR in liver regeneration.…”
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58
Genetic Transformation of Common Bean (Phaseolus vulgaris L.) with the Gus Color Marker, the Bar Herbicide Resistance, and the Barley (Hordeum vulgare) HVA1 Drought Tolerance Genes
Published 2012-01-01“…Transgenes included gus color marker which visually confirmed transgenic events, the bar herbicide resistance selectable marker used for in vitro selection of transgenic cultures and which confirmed Liberty herbicide resistant plants, and the barley (Hordeum vulgare) late embryogenesis abundant protein (HVA1) which conferred drought tolerance with a corresponding increase in root length of transgenic plants. …”
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PAX8 Distinguishes Diffuse Large B-Cell Lymphoma Mimicking Sarcoma
Published 2017-01-01“…PAX8 is important for embryogenesis of the thyroid, Müllerian system, and upper urinary/renal tract, and expression of PAX8 has been described in carcinomas from each of these sites. …”
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Inherited glycosylphosphatidylinositol deficiency disorders: a new group of inherited metabolic disorders
Published 2024-12-01“…These glycosylphosphatidylinositol-anchored proteins are an important part of receptors, function as hydrolytic enzymes, and play a crucial role in molecules adhesion, immune response, embryogenesis and neurogenesis. Patients present a variety of symptoms including developmental delay with intellectual disability, abnormalities of the central nervous, skeletal, circulatory, gastrointestinal, and urinary systems, facial dysmorphia as well as hearing and visual impairment. …”
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