Ucenprubart is an agonistic antibody to CD200R with the potential to treat inflammatory skin disease: preclinical development and a phase 1 clinical study by Anja Koester, Derrick R. Witcher, Mark Lee, Stephen J. Demarest, Scott Potter, Katie Werle, Scott Bauer, Diana Ruiz, Laurent Malherbe, Josh Poorbaugh, Andrew Glasebrook, Christoph Preuss, Gourab Datta, Ziqiao Wang, Jack Knorr, David Manner, Dipak Patel, Carsten Schmitz, Paul Klekotka, Ajay Nirula

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A universal monoallelic human leukocyte antigen class II immunopeptidomic platform for defining the immunogenicity potential of therapeutic proteins by Megan B. Lannan, Wenyu Ming, Laura J. Spindler, Douglas R. Perkins, Jinbiao Chen, Mark A. Wortinger, Richard E. Higgs, Robert W. Siegel

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Measuring Lp(a) particles with a novel isoform-insensitive immunoassay illustrates efficacy of muvalaplin by Craig A. Swearingen, John H. Sloan, Grace M. Rhodes, Robert W. Siegel, Nico Bivi, Yuewei Qian, Robert J. Konrad, Michael Boffa, Marlys Koschinsky, John Krege, Giacomo Ruotolo, Stephen J. Nicholls, Laura F. Michael, Yi Wen

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WCN24-1441 INTERFERON GAMMA (IFN-γ) IN EARLY DIABETIC KIDNEY DISEASE IS ASSOCIATED WITH PROGRESSION TO KIDNEY FAILURE by Viji Nair, Jennifer L. Harder, Jamal El Saghir, Felix H. Eichinger, Helen Looker, Shannon M. Harlan, Hana Baker, Frank C. Brosius, Kevin L. Duffin, Robert G. Nelson, Matthias Kretzler, Wenjun Ju

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Baricitinib-associated changes in global gene expression during a 24-week phase II clinical systemic lupus erythematosus trial implicates a mechanism of action through multiple imm... by Daniel J Wallace, Thomas Dörner, Stephanie de Bono, Robert J Benschop, Ernst R Dow, Damiano Fantini, Richard E Higgs, Guilherme Rocha, Brenda Crowe, Nicole L Byers, Maria E Silk, Robert W Hoffman

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Lebrikizumab Rapidly Lowers Inflammatory Biomarkers with Clinical Correlations in Moderate-to-Severe Atopic Dermatitis by Emma Guttman-Yassky, Zhe Sun, Laura Rebeca Mena, Nathan Hahn, Brian J. Nickoloff, Christoph Preuss, Kimberly Siu, Chitra R. Natalie, Gaia Gallo, Eric Wolf, Kilian Eyerich, Mònica Aparici, Robert J. Benschop, Angela Okragly

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Mechanism of baricitinib supports artificial intelligence‐predicted testing in COVID‐19 patients by Justin Stebbing, Venkatesh Krishnan, Stephanie de Bono, Silvia Ottaviani, Giacomo Casalini, Peter J Richardson, Vanessa Monteil, Volker M Lauschke, Ali Mirazimi, Sonia Youhanna, Yee‐Joo Tan, Fausto Baldanti, Antonella Sarasini, Jorge A Ross Terres, Brian J Nickoloff, Richard E Higgs, Guilherme Rocha, Nicole L Byers, Douglas E Schlichting, Ajay Nirula, Anabela Cardoso, Mario Corbellino, the Sacco Baricitinib Study Group

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Real-World Treatment Patterns Among Pediatric and Adult Patients with Crohn’s Disease in the United States by Art Kastl, Theresa Hunter Gibble, Debbie Tinsley, Wallace V. Crandall, Wendy J. Komocsar, Yu Du, Casey K. Choong, Payal Jha, Wai Man Maria Chan

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Predicting the clinical subcutaneous absorption rate constant of monoclonal antibodies using only the primary sequence: a machine learning approach by Ronghua Bei, Justin Thomas, Shiven Kapur, Mahlet Woldeyes, Adam Rauk, Jason Robarge, Jiangyan Feng, Kaoutar Abbou Oucherif

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Survival benefit from abemaciclib in non–small cell lung cancer by Kirsten rat sarcoma–mutation gene expression subtype: retrospective analysis from the JUNIPER Trial by Jiangang Liu, Hong Wang, Amit Aggarwal, Maria Jesus Ortiz-Ruiz, Elisabet Zapatero-Solana, Maria Jose Lallena, Sandra Peregrina, Gloria Martinez del Hoyo, Susana Velasco, Philip J. Ebert, Xueqian Gong, Anwar M. Hossain, Shawn T. Estrem

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Epitope mapping using immunopeptidomics reveals novel immunodominant CD8 T cell epitopes of the AAV9 capsid by Akhila Balasubramanian, Marek Prachar, Birgit Klaproth, Victoria Copeland, Sune Justesen, Yi Wen, Robert W. Siegel, Laurent P. Malherbe

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Treatment with orforglipron, an oral glucagon like peptide-1 receptor agonist, is associated with improvements of CV risk biomarkers in participants with type 2 diabetes or obesity... by Sean Wharton, Julio Rosenstock, Manige Konige, Yanzhu Lin, Kevin Duffin, Jonathan Wilson, Hiya Banerjee, Valentina Pirro, Christof Kazda, Kieren Mather

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Bayesian-frequentist hybrid inference framework for single cell RNA-seq analyses by Gang Han, Dongyan Yan, Zhe Sun, Jiyuan Fang, Xinyue Chang, Lucas Wilson, Yushi Liu

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Stage-Dependent Fibrotic Gene Profiling of WISP1-Mediated Fibrogenesis in Human Fibroblasts by Kirti Singh, Marta Witek, Jaladhi Brahmbhatt, Jacquelyn McEntire, Kannan Thirunavukkarasu, Sunday S. Oladipupo

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Cryptic Enhancer Elements in Luciferase Reporter Vectors Respond to the Osteoblast-Specific Transcription Factor Osf2/Cbfa1 by Kannan Thirunavukkarasu, Rebecca R. Miles, David L. Halladay, Jude E. Onyia

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Assessing tolerability with the Functional Assessment of Cancer Therapy item GP5: psychometric evidence from LIBRETTO-531, a phase 3 trial of selpercatinib in medullary thyroid can... by Antoine Regnault, Laurine Bunod, Angely Loubert, Marcia S. Brose, Lisa M. Hess, Patricia Maeda, Yan Lin, Rebecca M. Speck, Adrienne M. Gilligan, Nalin Payakachat

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Clinical trial participation, clinical care, and patient outcomes by practice setting: a real-world database analysis of patients with Chronic Lymphocytic Leukemia or Mantle Cell L... by Debora S. Bruno, Manoj Khanal, Xiaohong Li, Maricer P. Escalon, Katherine Winfree, Lisa M. Hess

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Outcomes among Patients with Mantle Cell Lymphoma Post-Covalent BTK Inhibitor Therapy in the United States: A Real-World Electronic Medical Records Study by Lisa M. Hess, Yongmei Chen, Paolo B. Abada, Heiko Konig, Richard A. Walgren

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Unmet weight loss targets in real-world clinical practice: weight management and perceptions in China by Ziwei Lin, Si Si, Jia Liu, Hao Zhu, Jiawei Xu, Esther Artime, Swarna Khare, Victoria Higgins, Andrea Leith, Shen Qu, Shen Qu

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The Effect of Retatrutide on Kidney Parameters in Participants With Type 2 Diabetes Mellitus and/or Obesity by Hiddo J.L. Heerspink, Zeqing Lu, Yu Du, Kevin L. Duffin, Tamer Coskun, Axel Haupt, Mark L. Hartman

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