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Marburg virus reaches Rwanda: how close are we to a vaccine solution?
Published 2025-04-01“…Marburg virus disease (MVD) is a highly virulent and often fatal disease caused by the Marburg virus, a member of the Filoviridae family, closely related to the Ebola virus. Historically, outbreaks have been sporadic but lethal across various African countries, with high case fatality rates (CFRs). …”
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22
Ebola: Impact of hospital's admission policy in an overwhelmed scenario
Published 2018-11-01“…A recent case occurred in West Africa in 2014 when an Ebola virus outbreak overwhelmed facilities in Sierra Leone, Guinea and Liberia. …”
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23
The potential impact of a prophylactic vaccine for Ebola in Sierra Leone
Published 2018-03-01“…The 2014 outbreak of Ebola virus disease (EVD) in West Africa was multinational and of an unprecedented scale primarily affecting the countries of Guinea, Liberia, and Sierra Leone. …”
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24
Marburg virus VP35 can both fully coat the backbone and cap the ends of dsRNA for interferon antagonism.
Published 2012-09-01“…Filoviruses, including Marburg virus (MARV) and Ebola virus (EBOV), cause fatal hemorrhagic fever in humans and non-human primates. …”
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25
Bimolecular Complementation to Visualize Filovirus VP40-Host Complexes in Live Mammalian Cells: Toward the Identification of Budding Inhibitors
Published 2011-01-01“…Virus-host interactions play key roles in promoting efficient egress of many RNA viruses, including Ebola virus (EBOV or “e”) and Marburg virus (MARV or “m”). …”
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26
African based researchers' output on models for the transmission dynamics of infectious diseases and public health interventions: A scoping review.
Published 2021-01-01“…Furthermore, human immunodeficiency virus, malaria, tuberculosis, and Ebola virus disease were found to be the most researched infectious diseases. …”
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27
Vaccination strategies for Ebola in the democratic republic of Congo: the who-Ebola modeling collaboration
Published 2025-04-01“…Objectives: Assess the effectiveness of ring vaccination in controlling an Ebola virus outbreak in the Democratic Republic of Congo. …”
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28
Reducing off-target expression of mRNA therapeutics and vaccines in the liver with microRNA binding sites
Published 2025-03-01“…To test the impact of miR-122 binding sites on antibody response to a mRNA vaccine, Ebola virus matrix protein VP40 mRNAs were modified with or without miR-122 binding sites and injected in mice intramuscularly. …”
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29
Establishment of a bat lung organoid culture model for studying bat-derived infectious diseases
Published 2025-02-01“…Abstract Bat is considered a natural reservoir of various important pathogens, including severe acute respiratory syndrome coronavirus (SARS-CoV), SARS-CoV-2, Ebola virus, and Nipah virus. To study these viruses’ pathogenicity and proliferation efficacy and viral tolerance mechanisms in bats, bat-derived cell lines, and primary cultured cells are used. …”
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Heterologous cAd3-Ebola and MVA-EbolaZ vaccines are safe and immunogenic in US and Uganda phase 1/1b trials
Published 2024-03-01“…Abstract Ebola virus disease (EVD) is a filoviral infection caused by virus species of the Ebolavirus genus including Zaire ebolavirus (EBOV) and Sudan ebolavirus (SUDV). …”
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31
Insights of window-bsed mechanism approach to visualize composite bioData point in feature spaces
Published 2019-03-01“…We use Influenza and Ebola viruses as examples to demonstrate the robustness of this approach and to conduct comparisons. …”
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