Clade 2.3.4.4b but not historical clade 1 HA replicating RNA vaccine protects against bovine H5N1 challenge in mice by David W. Hawman, Thomas Tipih, Eddie Hodge, E. Taylor Stone, Nikole Warner, Natalie McCarthy, Brian Granger, Kimberly Meade-White, Shanna Leventhal, Kiara Hatzakis, Stephanie Park, Karen Gaffney, Kyle Rosenke, Jesse H. Erasmus, Heinz Feldmann

“…Here we show that a replicating RNA vaccine expressing the HA of an H5N1 isolated from a US dairy cow confers complete protection against homologous lethal challenge in mice. A repRNA encoding the HA of a clade 1 H5 from 2004 (A/Vietnam/1203/2004) as utilized by some stockpiled vaccines, confers only partial protection. …”
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A Multi-Level Multiple Contrastive Learning Method for Single-Lead Electrocardiogram Atrial Fibrillation Detection by Yonggang Zou, Peng Wang, Lidong Du, Xianxiang Chen, Zhenfeng Li, Junxian Song, Zhen Fang

“…The MLMCL method utilizes the multi-level feature representations of the encoder to perform multiple contrastive learning to fully exploit temporal consistency, channel consistency, and label consistency. …”
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Characterization and phylogenetic analysis of the chloroplast genome of endangered Impatiens chishuiensis by LAN Wenxiang, MO Qing, HUANG Haiquan, HUANG Meijuan

“…[Results] (1) The chloroplast genome of I. chishuiensis has a typical tetrameric structure with a total GC content of 37% and a length of 152 892 bp. It encodes a total of 120 genes, including 95 protein-coding genes, 8 rRNA genes, and 17 tRNA genes. (2) A total of 87 SSR sequences was detected. 20 327 codons were detected, with leucine (Leu) being the most abundant and tryptophan (Trp) being the least. (3) Impatiens was divided into two subgenera, including subg. …”
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FGF21 and APOA1 mRNA-based therapies for the treatment of experimental acute pancreatitis by Amaya Lopez-Pascual, Eva Santamaria, Nuria Ardaiz, Iker Uriarte, Tiffany Palmer, Anne-Renee Graham, Celia Gomar, Roberto C. Barbero, M. Ujue Latasa, Maria Arechederra, Jesus M. Urman, Carmen Berasain, Antonio Fontanellas, Carlos L. del Rio, Maite G. Fernandez-Barrena, Paolo G.V. Martini, Joshua R. Schultz, Pedro Berraondo, Matias A. Avila

“…Methods Liver-targeted lipid nanoparticles (LNP)-mRNA formulations encoding FGF21, APOA1, and a chimeric APOA1-FGF21, were first tested for protein expression and bioavailability in vitro and in mice fed a high-fat diet. …”
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Expression Analysis and SNP Mining of the Parkin Co-Regulated Gene (PACRG) and parkin in Penaeus vannamei Against White Spot Syndrome Virus by Qian XUE, Xupeng LI, Yang LI, Sheng LUAN, Kun LUO, Jie KONG, Qun XING, Xianhong MENG

“…Our findings illustrated that the complete open reading frame (ORF) sequence of PACRG was 600 bp, encoded 199 amino acids, and was predicted to contain the ParcG structural domain. …”
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KDM6A facilitates Xist upregulation at the onset of X inactivation by Josephine Lin, Jinli Zhang, Li Ma, He Fang, Rui Ma, Camille Groneck, Galina N. Filippova, Xinxian Deng, Chizuru Kinoshita, Jessica E. Young, Wenxiu Ma, Christine M. Disteche, Joel B. Berletch

“…One of these genes is the highly conserved gene Kdm6a, which encodes a histone demethylase that removes methyl groups at H3K27 to facilitate gene expression. …”
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Investigating novel Streptomyces bacteriophage endolysins as potential antimicrobial agents by Jindanuch Maneekul, Amanda Chiaha, Rachel Hughes, Faith Labry, Joshua Saito, Matthew Almendares, Brenda N. Banda, Leslie Lopez, Nyeomi McGaskey, Melizza Miranda, Jenil Rana, Brandon R. Zadeh, Lee E. Hughes

“…ABSTRACT As antibiotic resistance has become a major global threat, the World Health Organization (WHO) has urgently called for alternative strategies for control of bacterial infections. Endolysin, a phage-encoded protein, can degrade bacterial peptidoglycan (PG) and disrupt bacterial growth. …”
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Idiopathic Generalized Epilepsy and Hypokalemic Periodic Paralysis in a Family of South Indian Descent by Muthiah Subramanian, N. Senthil, S. Sujatha

“…Hypokalemic periodic paralysis is a genetically heterogeneous channelopathy that has been linked to mutations in genes encoding three ion channels CACNIAS, SCN4A, and KCNJ2 predominantly. …”
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Multi-Component Temporal-Correlation Seismic Data Compression Algorithm Based on the PCA and DWT by Mateus Martinez de Lucena, Josafat Leal Ribeiro, Matheus Wagner, Antônio Augusto Fröhlich

“…This paper investigates the combination of principal component analysis (PCA), discrete wavelet transform (DWT), thresholding, quantization, and entropy encoding to compress such datasets. The proposed method is a lossy compression algorithm tuned by evaluating the reconstruction error in frequency ranges of interest, namely 0–20 Hz and 15–65 Hz. …”
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A Review of Brain–Computer Interface-Based Language Decoding: From Signal Interpretation to Intelligent Communication by Yingyi Qiu, Han Liu, Mengyuan Zhao

“…The current literature provides detailed insights into individual components of BCI systems, from neural encoding mechanisms to language decoding paradigms and clinical applications. …”
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Cell-marking techniques for cell lineage tracing by A. M. Yunusova, N. R. Battulin

“…This review focuses on modern methods for cell tracing with dyes and genetic constructs encoding protein reporters that mark cell lineages. …”
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Plasmablastic Lymphoma: A Review of Current Knowledge and Future Directions by Ghaleb Elyamany, Eman Al Mussaed, Ali Matar Alzahrani

“…The introduction of genes encoding artificial receptors called chimeric antigen receptors (CARs) and CAR-modified T cells targeted to the B cell-specific CD19 antigen have demonstrated promising results in multiple early clinical trials. …”
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FACS‐Sortable Triple Emulsion Picoreactors for Screening Reactions in Biphasic Environments by Samuel Thompson, Yanrong Zhang, Zijian Yang, Lisa Nichols, Polly M. Fordyce

“…These triple emulsion picoreactors have the potential for future screening bead‐encoded catalyst libraries, including enzymes such as lipases for biofuel production.…”
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PegasosQSVM: A Quantum Machine Learning Approach for Accurate Fake News Detection by Mehdi Khalil, Chi Zhang, Zhiwei Ye, Peng Zhang

“…This research explores quantum machine learning for fake news classification by proposing Pegasos Quantum Support Vector Machines, a novel algorithm combining Pegasos Support Vector Machines with quantum kernels, and advanced data encoding. Through experimentation on the IBM Qasm Simulator, Pegasos Quantum Support Vector Machines scored 90.67% in accuracy. …”
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French Loanwords in Canadian English: A Usage-Based Approach by Julie Rouaud

“…By positing the existence of exemplars which are stored in the mental lexicon with all their features, including meanings and inferences in context, we assume that meaning is not necessarily encoded linguistically and therefore fixed but that it can be stored and become conventionalized through use. …”
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Changes on Sugar and Starch Contents during Seed Development of Synergistic Sweet Corn and Implication on Seed Quality by Bhornchai Harakotr, Warisa Sutthiluk, Panumart Rithichai

“…Synergistic sweet corn equipped with multiple-recessive genes encoding sugar synthesis is proposed through hybrid breeding to improve the balance eating quality including flavor, texture, and aroma. …”
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Preparatory Switches of Auditory Spatial and Non-Spatial Attention Among Simultaneous Voices by Aureliu Lavric, Elisa Schmied

“…Picture cues resulted in better performance than word cues, especially when the interval between the cue and the stimulus was short, suggesting that (presumably phonological) processes involved in the recognition of the word cue interfered with the (near) concurrent encoding of the target voice’s speech.…”
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Application of Proteomics to Inflammatory Bowel Disease Research: Current Status and Future Perspectives by Arash Assadsangabi, Caroline A. Evans, Bernard M. Corfe, Alan Lobo

“…Proteomics provides methods for the large-scale study of the proteins encoded by the genome of an organism or a cell, to directly investigate the proteins and pathways involved. …”
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Distributed Compressed Hyperspectral Sensing Imaging Incorporated Spectral Unmixing and Learning by Hua Xiao, Zhongliang Wang, Xueying Cui, Liping Wang, Hongsheng Yang, Yingbiao Jia

“…Compressed hyperspectral imaging is a powerful technique for satellite-borne and airborne sensors that can effectively shift the complex computational burden from the resource-constrained encoding side to a presumably more capable base-station decoder. …”
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Aging-regulated TUG1 is dispensable for endothelial cell function. by Anna Theresa Gimbel, Susanne Koziarek, Kosta Theodorou, Jana Felicitas Schulz, Laura Stanicek, Veerle Kremer, Tamer Ali, Stefan Günther, Sandeep Kumar, Hanjoong Jo, Norbert Hübner, Lars Maegdefessel, Stefanie Dimmeler, Sebastiaan van Heesch, Reinier A Boon

“…Our data show that, despite a high expression and strong evolutionary conservation of both the TUG1 locus and the protein sequence it encodes, TUG1 does not seem to play a major role in basic endothelial cell function.…”
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