Uncovering somatic mosaic variants of PIK3CA-related overgrowth disorders – three cases with different clinical presentations by M. Tooming, M. Tooming, P. Mertsina, T. Kahre, T. Kahre, R. Teek, I. Vainumäe, I. Vainumäe, S. Lilles, S. Lilles, M. H. Wojcik, M. H. Wojcik, M. H. Wojcik, P. Ilves, P. Ilves, K. Õunap, K. Õunap

“…IntroductionPIK3CA related disorders (PRD, OMIM: *171834) are genetic disorders resulting from pathogenic somatic mosaic variants in the PIK3CA gene, which encodes a protein crucial for regulating cell growth and division. …”
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Adenovirus Vectors Target Several Cell Subtypes of Mammalian Inner Ear In Vivo by Yilai Shu, Yong Tao, Wenyan Li, Jun Shen, Zhengmin Wang, Zheng-Yi Chen

“…To identify adenovirus vectors that target specific cell subtypes in the inner ear, we studied three adenovirus vectors, carrying a reporter gene encoding green fluorescent protein (GFP) from two vendors or with a genome editing gene Cre recombinase (Cre), by injection into postnatal days 0 (P0) and 4 (P4) mouse cochlea through scala media by cochleostomy in vivo. …”
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Urinary Catheter Colonization by Multidrug-Resistant Cedecea neteri in Patient with Benign Prostatic Hyperplasia by Peter S. Ginn, Serina B. Tart, Stephen M. Sharkady, Dorothea K. Thompson

“…Analysis of whole genome sequence information for a representative C. neteri strain indicated the presence of multiple open reading frames with sequence similarity to β-lactamases, including a chromosome-encoded AmpC β-lactamase and metallo-β-lactamases, consistent with the resistance phenotype of this bacterium. …”
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The Impact of Interferon Lambda 3 Gene Polymorphism on Natural Course and Treatment of Hepatitis C by F. Bellanti, G. Vendemiale, E. Altomare, G. Serviddio

“…Very recently, three landmark genome-wide association studies identified single nucleotide polymorphisms near the interleukin 28B (IL28B) region which were more frequent in responders to treatment. IL28B encodes interferon (IFN)λ3, a type III IFN involved in host antiviral immunity. …”
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Excitable Ras dynamics-based screens reveal RasGEFX is required for macropinocytosis and random cell migration by Koji Iwamoto, Satomi Matsuoka, Masahiro Ueda

“…Here, we characterized RasGEFs encoded in Dictyostelium discoideum by live-cell imaging of the spatiotemporal dynamics of Ras-GTP and hierarchical clustering, finding that RasGEFX is primarily required for the spontaneous generation of Ras-GTP-enriched domains and is essential for random migration in combination with RasGEFB/M/U in starved cells, and they are dispensable for chemotaxis to chemoattractant cAMP. …”
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Stripe segmentation of oceanic internal waves in SAR images based on SegFormer by Hong-Sheng Zhang, Ji-Yu Sun, Kai-Tuo Qi, Ying-Gang Zheng, Jiao-Jiao Lu, Yu Zhang

“…Initially, a hierarchical transformer encoder transforms the image into multilevel feature maps. …”
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An Overview of Pathogen Recognition Receptors for Innate Immunity in Dental Pulp by Ji-Hyun Jang, Hee Woong Shin, Jung Min Lee, Hyeon-Woo Lee, Eun-Cheol Kim, Sang Hyuk Park

“…Pathogen recognition receptors (PRRs) are a class of germ line-encoded receptors that recognize pathogen-associated molecular patterns (PAMPs). …”
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Evidence for the Involvement of Lipid Rafts and Plasma Membrane Sphingolipid Hydrolases in Pseudomonas aeruginosa Infection of Cystic Fibrosis Bronchial Epithelial Cells by Domitilla Schiumarini, Nicoletta Loberto, Giulia Mancini, Rosaria Bassi, Paola Giussani, Elena Chiricozzi, Maura Samarani, Silvia Munari, Anna Tamanini, Giulio Cabrini, Giuseppe Lippi, Maria Cristina Dechecchi, Sandro Sonnino, Massimo Aureli

“…Cystic fibrosis (CF) is the most common autosomal genetic recessive disease caused by mutations of gene encoding for the cystic fibrosis transmembrane conductance regulator. …”
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A geometric neural solving method based on a diagram text information fusion analysis by Bin Ma, Pengpeng Jian, Cong Pan, Yanli Wang, Wei Ma

“…Information fusion was realized by connecting the two modal labels, and then the information was sent to the encoder for fusion. The geometric knowledge was generated under the guidance of multi-modal information, and these programs were executed to obtain the results. …”
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A Novel Lightweight U-Shaped Network for Crack Detection at Pixel Level by Zhong Luo, Xinle Li, Yanfeng Zheng

“…In this paper, adaptive enhancement module (AEM) is designed and added to the encoder network in order to avoid the problem of insufficient model learning capability due to the use of depth-wise separable convolutions. …”
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SSATNet: Spectral-spatial attention transformer for hyperspectral corn image classification by Bin Wang, Gongchao Chen, Juan Wen, Linfang Li, Songlin Jin, Yan Li, Ling Zhou, Weidong Zhang

“…Additionally, a transformer encoder with cross-attention extracts and refines feature information from a global perspective. …”
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Differential Gene Expression Profile of Human Neutrophils Cultured with Plasmodium falciparum-Parasitized Erythrocytes by Mohamad Alaa Terkawi, Ryo Takano, Kentaro Kato

“…The transcriptional response was characterized by the upregulation of numerous genes encoding multiple surface receptors, proteins involved in signal transduction pathways, and defense response proteins. …”
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The OsEBF1-OsEIL5-OsPP91 module regulates rice heat tolerance via ubiquitination and transcriptional activation by Jianping Liu, Ke Wang, Guining Wang, Zhi Peng, Tao Wang, Yang Meng, Jinli Huang, Jiaohan Huo, Xin Li, Xiaoqi Zhu, Feiyun Xu, Qian Zhang, Zhengrui Wang, Hao Chen, Ya Wang, Weifeng Xu

“…OsEIL5 directly binds to the promoter of OsPP91 (encoding one type 2C protein phosphatase) and activates its expression. …”
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Amplifying and Reversing the Chiral Bias in Asymmetric Photo‐Polymerization Reaction by Dingdong Liu, Xiangxiang Xu, Zeyu Feng, Chutian Zhang, Jialei Li, Yifan Xie, Jingguo Li, Hongli Zhang, Gang Zou

“…There is a bifurcation point in the chiral bias for the orthogonal control of the polymer helicity during the asymmetric photo‐polymerization process, favoring for programmable chiroptical micropatterns and multi‐channel independent information encoding. This work not only highlights opportunities for selectively regulating the asymmetric photopolymerization but also is highly valuable for fundamental understanding of the symmetry breaking in photochemical reactions.…”
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Multiscale Region-Level VHR Image Change Detection via Sparse Change Descriptor and Robust Discriminative Dictionary Learning by Yuan Xu, Kun Ding, Chunlei Huo, Zisha Zhong, Haichang Li, Chunhong Pan

“…Sparse change descriptor combines the change degree component and the change pattern component, which are encoded by the sparse representation error and the morphological profile feature, respectively. …”
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Muscarinic ACh Receptors Contribute to Aversive Olfactory Learning in Drosophila by Bryon Silva, Claudia Molina-Fernández, María Beatriz Ugalde, Eduardo I. Tognarelli, Cristian Angel, Jorge M. Campusano

“…It has been shown that olfactory information is conveyed to the MB through cholinergic inputs that activate acetylcholine (ACh) receptors, while the US is encoded by biogenic amine (BA) systems. In recent years, we have advanced our understanding on the specific neural BA pathways and receptors involved in olfactory learning and memory. …”
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Correlating disordered activation domain ensembles with gene expression levels by Eduardo Flores, Aleah R. Camacho, Estefania Cuevas-Zepeda, Mary B. McCoy, Feng Yu, Max V. Staller, Shahar Sukenik

“…Disordered ensembles contain sequence-encoded structural preferences that are often linked to their function. …”
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LPS Counter Regulates RNA Expression of Extracellular Proteases and Their Inhibitors in Murine Macrophages by Andreas Hald, Birgitte Rønø, Leif R. Lund, Kristoffer L. Egerod

“…The opposite scenario was found for the genes encoding serine proteases, which were downregulated while their inhibitors were upregulated. …”
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Innate Immune Recognition of Mycobacterium tuberculosis by Johanneke Kleinnijenhuis, Marije Oosting, Leo A. B. Joosten, Mihai G. Netea, Reinout Van Crevel

“…Human epidemiological studies revealed that genetic variation in genes encoding for PRRs and downstream signaling products influence disease susceptibility, severity, and outcome. …”
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A new crustin-like gene from the redclaw crayfish Cherax quadricarinatus and its response to decapod iridescent virus 1 (DIV1) challenge by Xiaoying Hang, Jianbo Zheng, Fei Li

“…The full-length cDNA sequence was 488 bp, and the open reading frame encoded 101 amino acids with a signal peptide in the N-terminus and a conserved WAP domain in the C-terminus. …”
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