Reduced NLRP3 Gene Expression Limits the IL-1β Cleavage via Inflammasome in Monocytes from Severely Injured Trauma Patients by Shinwan Kany, Johann-Philipp Horstmann, Ramona Sturm, Katharina Mörs, Borna Relja

“…Transfection of monocytes with NLRP3-encoding plasmid recovered the functionality of monocytes from TP regarding the IL-1β secretion. …”
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Codon Usage Bias and Cluster Analysis of the MMP-2 and MMP-9 Genes in Seven Mammals by Tanliang Ouyang, Jincheng Zhong, Zhixin Chai, Jiabo Wang, Ming Zhang, Zhijuan Wu, Jinwei Xin

“…RSCU analysis revealed that these two genes preferred codons encoding delicious amino acids. Analysing what factors influence CUB showed that the third base distributors of these two genes were C/A and C/T, and GC3S had a wide distribution range on the ENC plot reference curve under no selection or mutational pressure. …”
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Distribution and frequency of genetic mutations in three insecticide targets in field populations of Culex tritaeniorhynchus in Mianyang City, Sichuan Province, China by Hongwei Xie, Meilin Tang, Hongying Sun, Zhengzheng Huang, Mengmeng Dong, Xianying Wen

“…In the study, a total of 314 adults of Cx. tritaeniorhynchus, collected from 6 sites across Mianyang City, were inspected for resistance-conferring mutations in three genes encoding voltage-gated sodium channel (VGSC), Gamma-aminobutyric acid (GABA) receptor Rdl subunit (Rdl), and acetylcholinesterase (AChE) by DNA Sanger sequencing. …”
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APPLICATION OF ARTIFICIAL INTELLIGENCE FOR IMPROVING SITUATIONAL TRAINING OF CYBERSECURITY SPECIALISTS by Yurii V. Shchavinsky, Tetiana M. Muzhanova, Yuriy M. Yakymenko, Mykhailo M. Zaporozhchenko

“…Thanks to its excellent capabilities, which include summarizing and analyzing articles, encoding, debugging, and generating thematic blocks of situations, it represents significant progress in the field of artificial intelligence. …”
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Effect of neonatal dexamethasone treatment on cognitive abilities of adult male mice and gene expression in the hypothalamus by N. P. Bondar, V. V. Reshetnikov, K. V. Burdeeva, T. I. Merkulova

“…The expression level of the Crh gene encoding corticotropin-releasing hormone was unchanged, while the expression of the vasopressin gene (Avp) was increased in response to neonatal administration of dexamethasone. …”
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Gene Expression Analysis of Deduced Protein Sequence from the FLOWERING LOCUS C (FLC) Homolog during Vegetative and Reproductive Phases in Lepidium sativum L. by Parissa Jonoubi, Farkhondeh Rezanejad, Fatemeh Mahyapoor

“…The sequenced fragment encoded for a deduced protein sequence of 120 amino acids. …”
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IP3 receptor depletion in a spontaneous canine model of Charcot-Marie-Tooth disease 1J with amelogenesis imperfecta. by Marjo K Hytönen, Julius Rönkkö, Sruthi Hundi, Tarja S Jokinen, Emilia Suonto, Eeva Teräväinen, Jonas Donner, Rita La Rovere, Geert Bultynck, Emil Ylikallio, Henna Tyynismaa, Hannes Lohi

“…Variants in the ITPR3 gene, which encodes IP3R3, have recently been found to cause demyelinating sensorimotor Charcot-Marie-Tooth neuropathy type 1J (CMT1J). …”
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Comparative Study on the Effects of Four Plant Protein Sources on the Liver and Intestinal Health of Largemouth Bass, Micropterus salmoides by Shibin Yao, Wenjian Li, Chunfang Cai, Chengrui Wang, Jia Kang, Honglin Hu, Ping Wu, Xiamin Cao, Yuantu Ye

“…The contents of total bile acid, lipid, and collagen in the liver were increased, and the mRNA expression levels of genes encoding inflammatory factors and enzymes involved in de novo fatty acid synthesis and bile acid synthesis were upregulated. …”
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Effect of Liraglutide on Serum TSH Levels in Patients with NAFLD and its Underlying Mechanisms by JiaoJiao Ye, Jing Xu, WenJie Wen, Bin Huang

“…Furthermore, the expression of THRB, which encodes TRβ, was significantly decreased in the NAFLD group, which may explain the thyroid hormone resistance-like manifestation in the clinical findings. …”
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Dynamics of REL, RELA and IRF1 transcription factor expression in U937 macrophages after dioxin exposure by E. V. Kashina, D. Y. Oshchepkov, E. V. Antontseva, M. Y. Shamanina, D. P. Furman, V. A. Mordvinov

“…Putative DREs were predicted using the SITECON software tool in the regulatory regions of the genes encoding transcription factors REL, RELA and IRF1 expressed in macrophages. …”
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Implementing an environmental DNA/RNA-based approach to non-invasively investigate disease caused by Ichthyophthirius multifiliis by Yajiao Duan, Moonika Haahr Marana, Hannah Malene Jensen, Cyril Henard, Louise von Gersdorff Jørgensen

“…The eNA was extracted from the tank water and was used to detect the parasite throughout the course of the disease targeting a gene encoding an Ich immobilization antigen (Iag52a). Simultaneously, the parasite burden and immune-relevant gene expression in both water and fish gills were investigated. …”
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Incidence of extended spectrum beta-lactamase (ESBL) producing Escherichia coli isolated from women with urinary tract infections in Jordan by Rania Al-Groom

“…The aim of this study was to isolate Escherichia coli (E. coli) strains from midstream urine samples, and to determine molecular characterization of encoded Extended Spectrum Beta-Lactamase (ESBL) genes. …”
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Тransplastomic tobacco plants producing the hydrophilic domain of the sheep pox virus coat protein L1R by D. K. Beisenov, G. E. Stanbekova, B. K. Iskakov

“…A vector containing a deletion variant of the SPPV_56 gene, which encodes the N-terminal hydrophilic part of the viral coat protein L1R, was constructed to transform tobacco plastids. …”
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Melanin production and laccase mediated oxidative stress alleviation during fungal-fungal interaction among basidiomycete fungi by Samim Dullah, Dibya Jyoti Hazarika, Gunajit Goswami, Tanushree Borgohain, Alokesh Ghosh, Madhumita Barooah, Ashok Bhattacharyya, Robin Chandra Boro

“…Quantitative real-time PCR revealed upregulation of lcc1 (encoding a laccase enzyme) and few other stress related genes of T. versicolor during its hyphal interaction with T. coccinea, suggesting a direct correlation between laccase production and melanin production.…”
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Unique or not unique? Comparative genetic analysis of bacterial O-antigens from the Oxalobacteraceae family by S. D. Afonnikova, A. S. Komissarov, P. D. Kuchur

“…The variability of the physical structure is caused by the genomic variability of genes encoding O-antigen synthesis components. The genes and pathways of O-polysaccharide (OPS) synthesis were intensively investigated mostly for Enterobacteriaceae species. …”
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Technological properties of grain and flour in bread wheat (<i>Triticum aestivum</i> L.) genotypes carrying two loci that determine the endosperm structure by A. V. Simonov, T. A. Pshenichnikova

“…The mealy (soft) endosperm is generated by the biosynthesis of puroindolines – complete proteins encoded by these genes. When milled, such grain breaks down into small starch granules covered with proteins. …”
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Molecular Detection and Phylogenetic Analysis of the alkB Gene in Klebsiella oxytoca Strains Isolated from the Gut of Tenebrio molitor by Tsitsi Lynn Mupamhadzi, Oleen Machona, Farisai Chidzwondo, Rumbidzai Mangoyi

“…Thus, this study focuses on the molecular detection and phylogenetic analysis of the alkane-1-monooxygenase (alkB) gene in Klebsiella oxytoca strains isolated from the gut of Tenebrio molitor. The alkB gene encodes for alkane-1-monooxygenase, an enzyme involved in the oxidation of inactivated alkanes. …”
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Clinical and Genetic Characteristics of ABCC8 Nonneonatal Diabetes Mellitus: A Systematic Review by Meng Li, Xueyao Han, Linong Ji

“…The variants in ABCC8 gene encoding the SUR1 subunit of KATP could cause a variety of phenotypes, including neonatal diabetes mellitus (ABCC8-NDM) and ABCC8-induced nonneonatal diabetes mellitus (ABCC8-NNDM). …”
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In-silico screening and analysis of missense SNPs in human CYP3A4/5 affecting drug-enzyme interactions of FDA-approved COVID-19 antiviral drugs by Amro A. Abdelazim, Mohamad Maged, Ahmed I. Abdelmaksoud, Sameh E. Hassanein

“…Such variations could alter the encoded enzymes’ activities. CYP3A4/5 enzymes are involved in metabolizing drugs, notably antivirals against SARS-CoV-2. …”
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Analysis of the transcriptional activity of model piggyBac transgenes stably integrated into different loci of the genome of CHO cells in the absence of selection pressure by L. A. Yarinich, A. A. Ogienko, A. V. Pindyurin, E. S. Omelina

“…For this purpose, reporter constructs encoding eGFP under the control of four promoters were stably integrated into the genome of CHO cells using the piggyBac transposon. …”
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