Elucidation of the Inhibitory Effect of Phytochemicals with Kir6.2 Wild-Type and Mutant Models Associated in Type-1 Diabetes through Molecular Docking Approach by Manaswini Jagadeb, V Badireenath Konkimalla, Surya Narayan Rath, Rohit Pritam Das

“…Mutations in the KCNJ11 gene, encoding the kir6.2 channel, are reported to be associated with congenital hyperinsulinism, having a major impact in causing type 1 diabetes, and due to the lack of its 3D structure, an attempt has been made to predict the structure of kir6.2, applying fold recognition methods. …”
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Albino lethal 13, a chloroplast‐imported protein required for chloroplast development in rice by Xiaoqiong Guo, Chunli Wang, Qian Zhu, Wenhua Dongchen, Xiaoling Zhang, Wei Li, Hui Zhang, Cui Zhang, Zar Ni Naing Nant Nyein, Mengting Li, Lijuan Chen, Dongsun Lee

“…Molecular cloning revealed that OsAL13 encodes a novel rice protein with no homologous gene or known conserved domain. …”
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A Quantum-Classical Collaborative Training Architecture Based on Quantum State Fidelity by Ryan L'Abbate, Anthony D'Onofrio, Samuel Stein, Samuel Yen-Chi Chen, Ang Li, Pin-Yu Chen, Juntao Chen, Ying Mao

“…The classical component employs a tensor network for compression and feature extraction, enabling higher dimensional data to be encoded onto logical quantum circuits with limited qubits. …”
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Identification and Characterization of the Diverse Stress-Responsive R2R3-RMYB Transcription Factor from Hibiscus sabdariffa L. by Bahaeldeen Babikar Mohamed, Beenish Aftab, Muhammad Bilal Sarwar, Bushra Rashid, Zarnab Ahmad, Sameera Hassan, Tayyab Husnain

“…We identified and characterized the salt stress-responsive R2R3 type RMYB transcription factor from Hibiscus sabdariffa which has an open reading frame of 690 bp, encoding 229 long chain amino acids. In silico analysis confirmed the conserved R2 and R3 domain as well as an NLS-1 localization site. …”
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Quantum-Based Feature Selection for Multiclassification Problem in Complex Systems with Edge Computing by Wenjie Liu, Junxiu Chen, Yuxiang Wang, Peipei Gao, Zhibin Lei, Xu Ma

“…First, all features of each sample are encoded into a quantum state by performing operations CMP and Ry, and then the amplitude estimation is applied to calculate the similarity between any two quantum states (i.e., two samples). …”
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Symptom-based depression subtypes: brain dynamic specificity and its association with gene expression profiles by Qunjun Liang, Zhifeng Zhou, Shengli Chen, Shiwei Lin, Xiaoshan Lin, Ying Li, Yingli Zhang, Bo Peng, Gangqiang Hou, Yingwei Qiu

“…Finally, gene expression underlying the CCA model, along with its biological encoding process, performed using a postmortem gene expression atlas revealed distinct gene enrichments for different subtypes. …”
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Seahorse nanos3 plays essential roles in germ cell development in the absence of nanos2 by Lingzhen Chen, Lu Tang, Qiang Lin, Yanhong Zhang

“…However, the molecular mechanism of germ cell development in seahorses remains unknown. Nanos, which encodes conserved zinc-finger RNA-binding proteins, play essential roles for germline development in both vertebrates and invertebrates. …”
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Characterisation of the Pathogenicity of <i>Beauveria</i> sp. and <i>Metarhizium</i> sp. Fungi Against the Fall Armyworm, <i>Spodoptera frugiperda</i> (Lepidoptera: Noctuidae) by Nonthakorn (Beatrice) Apirajkamol, Bishwo Mainali, Phillip Warren Taylor, Thomas Kieran Walsh, Wee Tek Tay

“…Identifying and characterising gene clusters encoding these insecticide compounds in B-0571 and B-1311 will contribute to a better understanding of the entomopathogenicity of these isolates that will be vital to developing these EPF isolates as sustainable alternative FAW biocontrol agents.…”
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Recent advancements in the diverse roles of polymerase-associated proteins in the replication and pathogenesis of Newcastle disease virus by Jinghang Zhou, Yuqi Duan, Menglan Liu, Jinyang Liu, Zenglei Hu, Zhiqiang Duan

“…The NDV RNA genome primarily encodes six structural proteins (N, P, M, F, HN, and L) and two non-structural proteins (V and W). …”
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Molecular Cloning, Characterization, and mRNA Expression of Hemocyanin Subunit in Oriental River Prawn Macrobrachium nipponense by Youqin Kong, Liqiao Chen, Zhili Ding, Jianguang Qin, Shengming Sun, Ligai Wang, Jinyun Ye

“…The full-length cDNA of MnHc-1 was 2,163 bp with a 2,028-bp open reading frame (ORF) encoding a polypeptide of 675 amino acids. The MnHc-1 mRNA was expressed in the hepatopancreas, gill, hemocytes, intestine, ovary, and stomach, with the highest level in the hepatopancreas. …”
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Three-dimensional diffractive acoustic tomography by Luca Menozzi, Tri Vu, Aidan J. Canning, Harshal Rawtani, Carlos Taboada, Marie Elise Abi Antoun, Chenshuo Ma, Jesse Delia, Van Tu Nguyen, Soon-Woo Cho, Jianing Chen, Theresa Charity, Yirui Xu, Phuong Tran, Jun Xia, Gregory M. Palmer, Tuan Vo-Dinh, Liping Feng, Junjie Yao

“…Using 3D-DAT on small animal models, we mapped the distribution of the biliverdin-binding serpin complex in glassfrogs, tracked gold nanoparticle accumulation in a mouse tumor model, imaged genetically-encoded photoswitchable tumors, and investigated polyfluoroalkyl substances exposure on developing embryos. …”
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A short ncRNA modulates gene expression and affects stress response and parasite differentiation in Leishmania braziliensis by José C. Quilles, Caroline R. Espada, Lissur A. Orsine, Tânia A. Defina, Letícia Almeida, Fabíola Holetz, Angela K. Cruz

“…Comparative transcriptomics of ncRNA97KO and parental cells revealed that transcripts encoding amastigote-specific proteins were affected. …”
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Tackling the Problem of Distributional Shifts: Correcting Misspecified, High-dimensional Data-driven Priors for Inverse Problems by Gabriel Missael Barco, Alexandre Adam, Connor Stone, Yashar Hezaveh, Laurence Perreault-Levasseur

“…With the advent of machine learning, the use of data-driven population-level distributions (encoded, e.g., in a trained deep neural network) as priors is emerging as an appealing alternative to simple parametric priors in a variety of inverse problems. …”
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Genetic Variations and mRNA Expression of NRF2 in Parkinson’s Disease by Caroline Ran, Karin Wirdefeldt, Lovisa Brodin, Mehrafarin Ramezani, Marie Westerlund, Fengqing Xiang, Anna Anvret, Thomas Willows, Olof Sydow, Anders Johansson, Dagmar Galter, Per Svenningsson, Andrea Carmine Belin

“…Nuclear factor erythroid 2-like 2 (NRF2) encodes a transcription factor regulating mechanisms of cellular protection and is activated by oxidative stress. …”
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Hailey-Hailey disease successfully treated with naloxone: 2 case reports and Review of the literature on efficacy of opioid receptor antagonist in Hailey-Hailey disease patients by Junyou Zheng, Zhimin Duan, Beilei Xu, Hao Song, Jianbing Wu, Fang Fang, Nan Sheng, Chengrang Li

“…Background Hailey–Hailey disease (HHD), a genetic blistering disease, is caused by a mutation in a calcium transporter protein in the Golgi apparatus encoded by the ATP2C1 gene. Clinically, HHD is characterized by flaccid vesicles, blisters, erosions, fissures, and maceration mainly in intertriginous regions. …”
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MA-VoxelMorph: Multi-scale attention-based VoxelMorph for nonrigid registration of thoracoabdominal CT images by Qing Huang, Lei Ren, Tingwei Quan, Minglei Yang, Hongmei Yuan, Kai Cao

“…To further improve the large deformation and fine structure registration results, a multi-scale context channel attention mechanism is employed utilizing content information via adjacent encoding layers. Our method was evaluated on four public lung datasets (DIR-Lab dataset, Creatis dataset, Learn2Reg dataset, OASIS dataset) and a local dataset. …”
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Analysis of Several PLA2 mRNA in Human Meningiomas by Yves Denizot, Rafael De Armas, Karine Durand, Sandrine Robert, Jean-Jacques Moreau, François Caire, Nicolas Weinbreck, François Labrousse

“…In conclusion numerous genes encoding multiples forms of PLA2 are expressed in meningiomas where they might act on the phospholipid remodeling and on the local eicosanoid and/or cytokine networks.…”
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Case report: JAK inhibitor treatment of immune dysregulation symptoms in a patient with PTPN2 deficiency by Anna Roppelt, Ulyana Markina, Irina Beloglazova, Irina Beloglazova, Vasily Parshin, Dmitry Kanner, Dmitry Pershin, Mariia Fadeeva, Elena Raykina, Maxim Aleksenko, Alexander Karaulov, Mariana Lysenko, Mariana Lysenko, Daria Fomina, Daria Fomina, Daria Fomina

“…A heterozygous mutation in the PTPN2 gene has recently been described in several patients exhibiting symptoms of immune dysregulation. The gene encodes a ubiquitous non-receptor T-cell protein tyrosine phosphatase that exerts a negative feedback on the JAK–STAT pathway. …”
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Seq2scFv: a toolkit for the comprehensive analysis of display libraries from long-read sequencing platforms by Marianne Bachmann Salvy, Luca Santuari, Emanuel Schmid-Siegert, Nikolaos Lykoskoufis, Ioannis Xenarios, Bulak Arpat

“…In addition to providing annotated scFvs, translated sequences and numbered chains, Seq2scFv enables linker inference and characterization, sequence encoding with unique identifiers and quantification of identical sequences across selection rounds, thereby simplifying enrichment identification. …”
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TTSNet: Transformer–Temporal Convolutional Network–Self-Attention with Feature Fusion for Prediction of Remaining Useful Life of Aircraft Engines by Zhaofei Li, Shilin Luo, Haiqing Liu, Chaobin Tang, Jianguo Miao

“…Then, it uses a parallel transformer encoder, temporal convolutional network (TCN), and multi-head attention three-branch network to capture both global and local features of the time series. …”
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