Potential of a novel and thermostable recombinant phage endolysin of Escherichia phage KW1E_UTAR against Shigella spp. by Selvam Dharshini, Mohd Ismail Nor Ismaliza, Ng Michelle Y. T.

“…In this study, the Escherichia phage KW1E_UTAR gene encoding for endolysin was successfully cloned and expressed in Escherichia coli pET-28a. …”
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Leptin Antagonizes Peroxisome Proliferator-Activated Receptor-γ Signaling in Growth Plate Chondrocytes by Lai Wang, Yvonne Y. Shao, R. Tracy Ballock

“…Leptin is an obesity-associated cytokine-like hormone encoded by the ob gene. Recent studies reveal that leptin promotes proliferation and differentiation of chondrocytes, suggesting a peripheral role of leptin in regulating growth plate function. …”
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DNMT3a Downregulation Ttriggered Upregulation of GABAA Receptor in the mPFC Promotes Paclitaxel‐Induced Pain and Anxiety in Male Mice by Lixia Tian, Xu‐Hui Li, Yu‐Long Zhao, Hui‐Yuan Yi, Xue‐Ru Liu, Rongrong Yao, Xue‐Mei Hou, Xuan Zhu, Fu‐Quan Huo, Tao Chen, Lingli Liang

“…In this study, systemic administration of PTX leads to a decrease in the expression of the DNA methyltransferase DNMT3a, while concurrently upregulating the expression of Gabrb1 mRNA and its encoded GABAARβ1 protein in the medial PFC (mPFC) of male mice. …”
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Characterization of the Fungal Microbiome (Mycobiome) in Fecal Samples from Dogs by M. Lauren Foster, Scot E. Dowd, Christine Stephenson, Jörg M. Steiner, Jan S. Suchodolski

“…This study evaluated the fungal microbiome of 19 dogs (12 healthy dogs and 7 dogs with acute diarrhea) using fungal tag-encoded FLX-Titanium amplicon pyrosequencing. Five distinct fungal phyla were identified, with Ascomycota (medians: 97.9% of obtained sequences in healthy dogs and 98.2% in diseased dogs) and Basidiomycota (median 1.0% in healthy dogs and median 0.5% in diseased dogs) being the most abundant fungal phyla. …”
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Advancing the genetic engineering toolbox by combining AsCas12a knock-in mice with ultra-compact screening by Wei Jin, Yexuan Deng, John E. La Marca, Emily J. Lelliott, Sarah T. Diepstraten, Christina König, Lin Tai, Valentina Snetkova, Kristel M. Dorighi, Luke Hoberecht, Millicent G. Hedditch, Lauren Whelan, Geraldine Healey, Dan Fayle, Kieran Lau, Margaret A. Potts, Moore Z. Chen, Angus P. R. Johnston, Yang Liao, Wei Shi, Andrew J. Kueh, Benjamin Haley, Jean-Philippe Fortin, Marco J. Herold

“…We also present compact, genome-wide Cas12a knockout libraries, with four crRNAs per gene encoded across one (Scherzo) or two (Menuetto) vectors, and demonstrate the utility of these libraries across methodologies: in vitro enrichment and drop-out screening in lymphoma cells and immortalised fibroblasts, respectively, and in vivo screens to identify lymphoma-driving events. …”
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All‐Inorganic Perovskite Quantum‐Dot Optical Neuromorphic Synapses for Near‐Sensor Colored Image Recognition by Yung‐Chi Yao, Chia‐Jung Lee, Yong‐Jun Chen, Jun‐Zhi Feng, Hongseok Oh, Chin‐Shan Lue, Jinn‐Kong Sheu, Ya‐Ju Lee

“…Additionally, the seamless integration of electronics and photonics within a unified material system establishes a novel paradigm for optical retrieval, enabling real‐time perception of the encoded status of the ONS device. These findings represent substantial advancements in near‐sensor computing platforms and open a new horizon for all‐inorganic perovskite optoelectronic technologies.…”
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Cloning, expression pattern analysis, and vector construction of the BvNAC40 gene in sugar beet by FAN Ziqi, SUN Yaqing, LI Ningning, ZHANG Shaoying, LI Guolong

“…[Results] The CDS of BvNAC40 was 1 182 bp long, encoding 393 amino acids, which was classified within the NAC transcription factor family, with a transmembrane domain at the C-terminus. …”
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MacSyFinder v2: Improved modelling and search engine to identify molecular systems in genomes by Néron, Bertrand, Denise, Rémi, Coluzzi, Charles, Touchon, Marie, Rocha, Eduardo P.C., Abby, Sophie S.

“…Complex cellular functions are usually encoded by a set of genes in one or a few organized genetic loci in microbial genomes. …”
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IDENTIFICATION OF THE CTX-M GENE IN KLEBSIELLA PNEUMONIAE PRODUCING ESBLS IN UTI PATIENTS AT A PRIVATE HOSPITAL IN PURWOKERTO, BANYUMAS REGENCY, CENTRAL JAVA - CROSS SECTIONAL STUD... by Anang Kurniawan, Joko Setyono, Dwi Utami Anjarawati

“…Background: The CTX-M gene in ESBLs-producing Klebsiella pneumoniae is associated with virulence factors and encodes for antibiotic resistance. There are currently 128 different varieties of CTX-M, which gene can hydrolyze beta-lactam medicines like cefotaxime. …”
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Experimental Validation of Virtual Torque Sensing for Wind Turbine Gearboxes Based on Strain Measurements by Jelle Bosmans, Simone Gallas, Victor Smeets, Matteo Kirchner, Luk Geens, Jan Croes, Wim Desmet

“…Three groups of strain gauges on the gearbox as well an angular encoder are considered in this paper. Second is a physics‐based model, capable of predicting the response of aforementioned sensors. …”
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The gastric microbiome altered by A4GNT deficiency in mice by Dawei Gong, Dawei Gong, Yuqiang Gao, Rui Shi, Xiaona Xu, Mengchao Yu, Shumin Zhang, Lili Wang, Quanjiang Dong

“…BackgroundSelective antimicrobial effects have been found for α1,4-linked N-acetylglucosamine residues at the terminus of O-glycans attached to a core protein of gastric gland mucin. A4gnt encodes α1,4-N-acetylglucosaminyl transferase, which is responsible for the biosynthesis of α1,4-linked N-acetylglucosamine. …”
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N-3 Polyunsaturated Fatty Acids Stimulate Bile Acid Detoxification in Human Cell Models by Anna Cieślak, Jocelyn Trottier, Mélanie Verreault, Piotr Milkiewicz, Marie-Claude Vohl, Olivier Barbier

“…Gene expression analyses of HepG2 cells reveal that n-3 PUFAs reduce the expression of genes involved in BA synthesis (CYP7A1, CYP27A1) and uptake (NTCP), while activating genes encoding metabolic enzymes (SULT2A1) and excretion transporters (MRP2, MRP3). …”
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Effect of Selenate on Viability and Selenomethionine Accumulation of Chlorella sorokiniana Grown in Batch Culture by Živan Gojkovic, Carlos Vílchez, Rafael Torronteras, Javier Vigara, Veronica Gómez-Jacinto, Nora Janzer, José-Luis Gómez-Ariza, Ivana Márová, Ines Garbayo

“…Unlike control cultures, SDS PAGE electrophoresis of crude extracts from selenate-exposed cell cultures revealed appearance of a protein band identified as 53 kDa Rubisco large subunit of Chlorella sorokiniana, suggesting that selenate affects expression of the corresponding chloroplast gene as this subunit is encoded in the chloroplast DNA. Results revealed that the microalga was able to accumulate up to 140 mg·kg−1 of SeMet in 120 h of cultivation. …”
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Catching a CAPTCHA: the impact of variable input on the processing of emerging orthographic representations by Olga Solaja, María Fernández-López, Davide Crepaldi, Manuel Perea

“…The present study tests whether encoding letter strings from a novel alphabet becomes more resistant to distortion when trained with variable input. …”
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Apoptosis through Death Receptors in Temporal Lobe Epilepsy-Associated Hippocampal Sclerosis by Marcelo Ananias Teocchi, Lília D’Souza-Li

“…Amongst them are the encoding genes for ligands (FASLG, TNF, and TNFSF10) and death receptors (FAS, TNFRSF1A, TNFRSF10A, and TNFRSF10B). …”
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Targeting of retrovirus-derived Rtl8a/8b causes late-onset obesity, reduced social response and increased apathy-like behaviour by Yoshifumi Fujioka, Hirosuke Shiura, Masayuki Ishii, Ryuichi Ono, Tsutomu Endo, Hiroshi Kiyonari, Yoshikazu Hirate, Hikaru Ito, Masami Kanai-Azuma, Takashi Kohda, Tomoko Kaneko-Ishino, Fumitoshi Ishino

“…An RNAseq study in the cerebral cortex revealed reduced expression of several GABA type A receptor subunit genes in DKO, in particular Gabrb2, which encodes its β2 subunit. We confirmed the reduction of GABRB2 protein in the DKO cerebral cortex by western blotting. …”
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Dual-channel near-field holographic MIMO communications based on programmable digital coding metasurface and electromagnetic theory by Rui Wen Shao, Jun Wei Wu, Jiachen Li, Shengguo Meng, Yifan Xu, Zheng Xing Wang, Wankai Tang, Qiang Cheng, Shi Jin, Tie Jun Cui

“…Then the information to be transmitted is pre-encoded on PDCM following the principle of direct digital modulations. …”
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Identification and Removal of Light Pollution in Maritime Night-Time Images Based on Spatial Frequency Blocks by Hui Sun, Jingyang Wang, Mingyang Pan, Zongying Liu, Shaoxi Li, Ruolan Zhang, Yang Wei

“…The model includes ResNet-50, an encoder, a decoder, and a discriminator. To enable the model to better remove the influence of light pollution, this study designs a method of first detecting the light pollution area and then removing it. …”
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Transient Neonatal Zinc Deficiency Caused by a Heterozygous G87R Mutation in the Zinc Transporter ZnT-2 (SLC30A2) Gene in the Mother Highlighting the Importance of Zn2+ for Normal... by Maria Consolata Miletta, Andreas Bieri, Kristin Kernland, Martin H. Schöni, Vibor Petkovic, Christa E. Flück, Andrée Eblé, Primus E. Mullis

“…An exclusively breast-fed 6 months old infant suffering from Zn2+ deficiency caused by an autosomal dominant negative G87R mutation in the Slc30a2 gene (encoding for the zinc transporter 2 (ZnT-2)) in the mother is reported. …”
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Risk Factors in Normal-Tension Glaucoma and High-Tension Glaucoma in relation to Polymorphisms of Endothelin-1 Gene and Endothelin-1 Receptor Type A Gene by Dominika Wróbel-Dudzińska, Ewa Kosior-Jarecka, Urszula Łukasik, Janusz Kocki, Agnieszka Witczak, Jerzy Mosiewicz, Tomasz Żarnowski

“…DNA was isolated by standard methods and genotype distributions of four polymorphisms in genes encoding endothelin-1 (K198N) and endothelin-1 receptor type A polymorphisms (C1222T, C70G, and G231A) were determined. …”
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