Too many cooks in the kitchen: HPV driven carcinogenesis – The result of collaboration or competition? by Weimer Kathleen

“…At the core of Papillomavirus pathogenesis sits three virally encoded oncoproteins: E5, E6, and E7. In this review we will discuss the respective roles of these proteins and how they contribute to carcinogenesis, evaluating key distinguishing features that separate them from their low-risk counterparts. …”
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Poikiloderma with neutropenia: a case report by Jebran Chekr, Jan Andraws, Jubran Elias, Diana Alasmar

“…Mutations in the C16orf57 gene, which encodes the USB1 protein, are implicated as the underlying cause of poikiloderma with neutropenia. …”
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Advance Sharing Procedures for the Ramp Quantum Secret Sharing Schemes With the Highest Coding Rate by Ryutaroh Matsumoto

“…Then, it is proved that our new encoding procedures retain the correspondences between quantum secrets and quantum shares in the original schemes, which ensures that the highest coding rates of the original schemes are also retained.…”
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Premature Moustache As Presenting Symptom of Nonclassic Congenital Adrenal Hyperplasia due to 2 Uncommon Mutations of the CYP21A2 Gene by Guy Massa, Philippe Gillis, Marianne Schwartz

“…Genetic analysis revealed 2 rare mutations of the CYP21A2 gene, the gene encoding for the 21-hydroxylase enzyme: a recently reported R132C mutation in exon 3 and a R339H mutation in exon 8, both reported in the nonclassic CAH. …”
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Autoencoder-Based DIFAR Sonobuoy Signal Transmission and Reception Method Incorporating Residual Vector Quantization and Compensation Module: Validation Through Air Channel Modelin... by Yeonjin Park, Jungpyo Hong

“…Additionally, an unstructured pruning technique is applied to the encoder to minimize computational load and parameters, addressing the battery limitations of sonobuoys. …”
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Semi-random and semi-algebraic structural design for IRA-LDPC codes by Li PENG, Qi ZHANG, Bo WANG, Tao CHEN

“…A method of semi-random and semi-algebraic structure was presented for constructing the low-density parity-check matrix that corresponds to the information bits of the IRA codes.Compared with the existing structural LDPC codes,the distinct advantage of the presented compact structural array for information-bit-corresponding matrix is that the position coordinate of each 1 element in this matrix can be calculated by a determinate algebraic expression,which not only reduces the consumption of memory resource for the random parity-check matrix,but also provides the potential probability for designing low complexity hardware circuit of the LDPC encoder/decoder.In addition,compared with the existing practical LDPC codes in industrial standard,the presented IRA-LDPC code is also slight preponderance in the performance of simulation in bit error rate and signal noise ratio (BER-SNB).…”
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Two Novel Variants in the ATRX Gene Associated with Variable Phenotypes by D. Hettiarachchi, B. A. P. S. Pathirana, P. J. Kumarasiri, V. H. W. Dissanayake

“…The X-linked alpha-thalassemia mental retardation (ATR-X) syndrome is a rare genetic condition caused by mutations in the X‐encoded gene ATRX. Here we describe two unrelated patients of Sri Lankan origin with novel missense variants in the ATRX gene: c.839C>T|p.Cys280Tyr and c.5369C>T|p.Ala1790Val. …”
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High-dimensional outlier detection based on deep belief network and linear one-class SVM by Haoqi LI, Na YING, Chunsheng GUO, Jinhua WANG

“…Aiming at the difficulties in high-dimensional outlier detection at present,an algorithm of high-dimensional outlier detection based on deep belief network and linear one-class SVM was proposed.The algorithm firstly used the deep belief network which had a good performance in the feature extraction to realize the dimensionality reduction of high-dimensional data,and then the outlier detection was achieved based on a one-class SVM with the linear kernel function.High-dimensional data sets in UCI machine learning repository were selected to experiment,result shows that the algorithm has obvious advantages in detection accuracy and computational complexity.Compared with the PCA-SVDD algorithm,the detection accuracy is improved by 4.65%.Compared with the automatic encoder algorithm,its training time and testing time decrease significantly.…”
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The Rieske Iron-Sulfur Protein: Import and Assembly into the Cytochrome 𝑏𝑐1 Complex of Yeast Mitochondria by Laura Conte, Vincenzo Zara

“…The Rieske iron-sulfur protein is encoded by nuclear DNA and, after being synthesized in the cytosol, is imported into mitochondria with the help of a cleavable N-terminal presequence. …”
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Solutions to No-Wait Flow Shop Scheduling Problem Using the Flower Pollination Algorithm Based on the Hormone Modulation Mechanism by Chiwen Qu, Yanming Fu, Zhongjun Yi, Jun Tan

“…This algorithm minimizes the maximum accomplished time. Random keys are encoded based on an ascending sequence of components to make the flower pollination algorithm (FPA) suitable for the no-wait flow shop scheduling problem. …”
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Suppressing Polarization Mode Dispersion with the Quantum Zeno Effect by Ian Nodurft, Alejandro Rodriguez Perez, Naveed Naimipour, Harry C. Shaw

“…Polarization mode dispersion can introduce quantum decoherence in polarization encoded information, limiting the range of quantum communications protocols. …”
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Disruption of BCAA degradation is a critical characteristic of diabetic cardiomyopathy revealed by integrated transcriptome and metabolome analysis by Wu Yanxia, Jiang Wanxiang, Wang Junlong, Xie Guoqing, Sun Yan, Yang Jinliang

“…Furthermore, the study identified the transcription factor Gata3 as a predicted negative regulator of the gene encoding the key enzyme for BCAA degradation. These findings suggest that the disruption of BCAA degradation is a critical characteristic of diabetic myocardial damage and indicate a potential role for Gata3 in the dysregulation of BCAA metabolism in the context of DCM.…”
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Massive bigravity as a presymplectic BV-AKSZ sigma-model by Maxim Grigoriev, Vyacheslav Gritzaenko

“…Abstract We propose a presymplectic BV-AKSZ sigma model encoding the ghost-free massive bigravity theory action as well as its Batalin-Vilkovisky extension in terms of the finite-dimensional graded geometry of the target space. …”
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Treatment of hypotrichosis simplex of the scalp with the combination of botanic extracts and minoxidil: a case report by Mingyue Zhuang, Mingyue Zhuang, Yonglong Xu, Shiyi Zhong, Ziyuan Tian, Qingwu Liu, Dingquan Yang

“…Hypotrichosis simplex of the scalp (HSS) is a clinically rare monogenic autosomal dominant disorder associated with variants in the gene CDSN, which encodes the desmosome protein corneodesmosin. Although studies have reported that some medications can improve the symptoms of hair loss in HSS, there is still a lack of definitive and effective treatments for this disease. …”
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A novel ARCN1 splice-site variant in a Chinese girl with central precocious puberty, intrauterine growth restriction, microcephaly, and microretrognathia by Guoying Chang, Fan Yang, Lingwen Ying, Qianwen Zhang, Biyun Feng, Yao Chen, Yu Ding, Tingting Yu, Ruen Yao, Kana Lin, Juan Li, Xiumin Wang

“…Abstract The ARCN1 gene encodes the delta subunit of the coatomer protein complex I (COPI), which is essential for mediating protein transport from the Golgi complex to the endoplasmic reticulum. …”
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Cardiac Gene Therapy With Phosphodiesterase 2A Limits Remodeling and Arrhythmias in Mouse Models of Heart Failure by Rima Kamel, Aurélia Bourcier, Jean Piero Margaria, Valentin Jin, Audrey Varin, Agnès Hivonnait, Françoise Mercier‐Nomé, Delphine Mika, Alessandra Ghigo, Flavien Charpentier, Vincent Algalarrondo, Emilio Hirsch, Rodolphe Fischmeister, Grégoire Vandecasteele, Jérôme Leroy

“…Methods and Results C57BL/6 male mice were injected with serotype 9 adeno‐associated viruses encoding for PDE2A. This led to a ≈10‐fold rise of PDE2A protein levels that affected neither cardiac structure nor function in healthy mice. …”
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Synergistic interaction between wheat streak mosaic virus and Triticum mosaic virus modulates wheat transcriptome to favor disease severity by Haritha Nunna, Nathan A. Palmer, Gautam Sarath, Stephen N. Wegulo, Satyanarayana Tatineni, Satyanarayana Tatineni

“…Analyses of transcription factor families indicated that genes encoding MADS-Box and ARFs were strongly enriched in control plants, moderately repressed in TriMV-infected plants, and more strongly repressed in WSMV- and doubly-infected plants, whereas genes encoding WRKYs and NACs were more enriched in WSMV or doubly infected plants. …”
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Molecular cloning and expression dynamics of Atrogin-1 in muscle tissue of Russian sturgeon (Acipenser gueldenstaedtii) under high salt stress by Yong-Juan Mo, Yi-Li Gao, Shi-Jjian Xu, Bin Wang, Jingping Wu, Peng Yu, Ming Li, Xiangtao Kang, Zhi-Qiang Han

“…To elucidate the regulatory mechanism of Atrogin-1 in response to high salt stress in Russian sturgeon, we conducted cDNA cloning and expression analysis. The cDNA encoding the Russian sturgeon protein Atrogin-1 was successfully cloned, comprising 1472 bp and encoding 353 amino acid residues (with an open reading frame of 1062 bp). …”
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RBMDC-Net: Effective Jaw Cyst Segmentation Network Using Residual Bottleneck and Multiscale Dilated Convolution by Huixia Zheng, Xiaoliang Jiang, Xu Xu, Zhenfei Yuan

“…Next, we process each feature extracted from the encoder by passing it through a series of multiscale dilated convolution modules (MDCM), which capture more diverse and reliable features by increasing the acceptance field. …”
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Peningkatan Performa Komputasi Sistem Navigasi Transportasi Publik Pada Perangkat Bergerak Melalui Penerapan Teknik Kompresi Data dan Penyederhanaan Graf by Aryo Pinandito, Agi Putra Kharisma, Muhammad Aminul Akbar, Mochamad Chandra Saputra

“…Teknik kompresi yang digunakan pada penelitian ini adalah Zlib yang dikombinasikan dengan encoding Base64. Analisis juga dilakukan terhadap beban tambahan dan penggunaan memori akibat proses kompresi serta analisis waktu komputasi dan penggunaan memori akibat penyederhanaan struktur data graf melalui pendekatan visual dengan algoritme Douglas-Peucker. …”
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