Gene Polymorphisms of the antioxidant enzymes NOX, GSTP, and GPX and diabetic nephropathy risk in Saudi patients with type 2 diabetes by Samar Sultan, Meshari Alharbi, Nuha Alrayes, Nehad Makki, Amani Alhozali, Reham Abdulnoor, Aloof Alsawat, Haitham Khalil, Noha Jawi, Ahmed Makeen

“…This case–control study comprised two groups with 100 participants (50 T2D and 50 DN patients) and aimed to examine the association between single-nucleotide polymorphisms (SNPs) in the genes encoding nicotinamide adenine dinucleotide phosphate oxidase (NOX), glutathione S-transferase P (GSTP1), and glutathione peroxidase 1(GPX1) and diabetic nephropathy (DN) risk in patients with T2D. …”
Get full text

Adenovirus Vectors Target Several Cell Subtypes of Mammalian Inner Ear In Vivo by Yilai Shu, Yong Tao, Wenyan Li, Jun Shen, Zhengmin Wang, Zheng-Yi Chen

“…To identify adenovirus vectors that target specific cell subtypes in the inner ear, we studied three adenovirus vectors, carrying a reporter gene encoding green fluorescent protein (GFP) from two vendors or with a genome editing gene Cre recombinase (Cre), by injection into postnatal days 0 (P0) and 4 (P4) mouse cochlea through scala media by cochleostomy in vivo. …”
Get full text

Urinary Catheter Colonization by Multidrug-Resistant Cedecea neteri in Patient with Benign Prostatic Hyperplasia by Peter S. Ginn, Serina B. Tart, Stephen M. Sharkady, Dorothea K. Thompson

“…Analysis of whole genome sequence information for a representative C. neteri strain indicated the presence of multiple open reading frames with sequence similarity to β-lactamases, including a chromosome-encoded AmpC β-lactamase and metallo-β-lactamases, consistent with the resistance phenotype of this bacterium. …”
Get full text

The Impact of Interferon Lambda 3 Gene Polymorphism on Natural Course and Treatment of Hepatitis C by F. Bellanti, G. Vendemiale, E. Altomare, G. Serviddio

“…Very recently, three landmark genome-wide association studies identified single nucleotide polymorphisms near the interleukin 28B (IL28B) region which were more frequent in responders to treatment. IL28B encodes interferon (IFN)λ3, a type III IFN involved in host antiviral immunity. …”
Get full text

An Overview of Pathogen Recognition Receptors for Innate Immunity in Dental Pulp by Ji-Hyun Jang, Hee Woong Shin, Jung Min Lee, Hyeon-Woo Lee, Eun-Cheol Kim, Sang Hyuk Park

“…Pathogen recognition receptors (PRRs) are a class of germ line-encoded receptors that recognize pathogen-associated molecular patterns (PAMPs). …”
Get full text

Evidence for the Involvement of Lipid Rafts and Plasma Membrane Sphingolipid Hydrolases in Pseudomonas aeruginosa Infection of Cystic Fibrosis Bronchial Epithelial Cells by Domitilla Schiumarini, Nicoletta Loberto, Giulia Mancini, Rosaria Bassi, Paola Giussani, Elena Chiricozzi, Maura Samarani, Silvia Munari, Anna Tamanini, Giulio Cabrini, Giuseppe Lippi, Maria Cristina Dechecchi, Sandro Sonnino, Massimo Aureli

“…Cystic fibrosis (CF) is the most common autosomal genetic recessive disease caused by mutations of gene encoding for the cystic fibrosis transmembrane conductance regulator. …”
Get full text

Differential Gene Expression Profile of Human Neutrophils Cultured with Plasmodium falciparum-Parasitized Erythrocytes by Mohamad Alaa Terkawi, Ryo Takano, Kentaro Kato

“…The transcriptional response was characterized by the upregulation of numerous genes encoding multiple surface receptors, proteins involved in signal transduction pathways, and defense response proteins. …”
Get full text

The OsEBF1-OsEIL5-OsPP91 module regulates rice heat tolerance via ubiquitination and transcriptional activation by Jianping Liu, Ke Wang, Guining Wang, Zhi Peng, Tao Wang, Yang Meng, Jinli Huang, Jiaohan Huo, Xin Li, Xiaoqi Zhu, Feiyun Xu, Qian Zhang, Zhengrui Wang, Hao Chen, Ya Wang, Weifeng Xu

“…OsEIL5 directly binds to the promoter of OsPP91 (encoding one type 2C protein phosphatase) and activates its expression. …”
Get full text

Amplifying and Reversing the Chiral Bias in Asymmetric Photo‐Polymerization Reaction by Dingdong Liu, Xiangxiang Xu, Zeyu Feng, Chutian Zhang, Jialei Li, Yifan Xie, Jingguo Li, Hongli Zhang, Gang Zou

“…There is a bifurcation point in the chiral bias for the orthogonal control of the polymer helicity during the asymmetric photo‐polymerization process, favoring for programmable chiroptical micropatterns and multi‐channel independent information encoding. This work not only highlights opportunities for selectively regulating the asymmetric photopolymerization but also is highly valuable for fundamental understanding of the symmetry breaking in photochemical reactions.…”
Get full text

Multiscale Region-Level VHR Image Change Detection via Sparse Change Descriptor and Robust Discriminative Dictionary Learning by Yuan Xu, Kun Ding, Chunlei Huo, Zisha Zhong, Haichang Li, Chunhong Pan

“…Sparse change descriptor combines the change degree component and the change pattern component, which are encoded by the sparse representation error and the morphological profile feature, respectively. …”
Get full text

Muscarinic ACh Receptors Contribute to Aversive Olfactory Learning in Drosophila by Bryon Silva, Claudia Molina-Fernández, María Beatriz Ugalde, Eduardo I. Tognarelli, Cristian Angel, Jorge M. Campusano

“…It has been shown that olfactory information is conveyed to the MB through cholinergic inputs that activate acetylcholine (ACh) receptors, while the US is encoded by biogenic amine (BA) systems. In recent years, we have advanced our understanding on the specific neural BA pathways and receptors involved in olfactory learning and memory. …”
Get full text

Correlating disordered activation domain ensembles with gene expression levels by Eduardo Flores, Aleah R. Camacho, Estefania Cuevas-Zepeda, Mary B. McCoy, Feng Yu, Max V. Staller, Shahar Sukenik

“…Disordered ensembles contain sequence-encoded structural preferences that are often linked to their function. …”
Get full text

LPS Counter Regulates RNA Expression of Extracellular Proteases and Their Inhibitors in Murine Macrophages by Andreas Hald, Birgitte Rønø, Leif R. Lund, Kristoffer L. Egerod

“…The opposite scenario was found for the genes encoding serine proteases, which were downregulated while their inhibitors were upregulated. …”
Get full text

Innate Immune Recognition of Mycobacterium tuberculosis by Johanneke Kleinnijenhuis, Marije Oosting, Leo A. B. Joosten, Mihai G. Netea, Reinout Van Crevel

“…Human epidemiological studies revealed that genetic variation in genes encoding for PRRs and downstream signaling products influence disease susceptibility, severity, and outcome. …”
Get full text

A new crustin-like gene from the redclaw crayfish Cherax quadricarinatus and its response to decapod iridescent virus 1 (DIV1) challenge by Xiaoying Hang, Jianbo Zheng, Fei Li

“…The full-length cDNA sequence was 488 bp, and the open reading frame encoded 101 amino acids with a signal peptide in the N-terminus and a conserved WAP domain in the C-terminus. …”
Get full text

A fast registration method for multi-view point clouds with low overlap in robotic measurement by Chuangchuang Li, Xubin Lin, Zhaoyang Liao, Hongmin Wu, Zhihao Xu, Xuefeng Zhou

“…First, feature extraction is performed using a bilinear encoder and multi-level feature interactions of both point-wise and global features. …”
Get full text

Antibiotic-associated changes in Akkermansia muciniphila alter its effects on host metabolic health by Yumin Han, Teh Min Teng, Juwon Han, Heenam Stanley Kim

“…These variants had mutations in the promoter of a TEM-type β-lactamase gene or pur genes encoding the de novo purine biosynthesis pathway, and they exhibited compromised abilities to mitigate host obesity in a murine model. …”
Get full text

LCMorph: Exploiting Frequency Cues and Morphological Perception for Low-Contrast Road Extraction in Remote Sensing Images by Xin Li, Shumin Yang, Fan Meng, Wenlong Li, Zongchi Yang, Ruoyu Wei

“…First, Frequency-Aware Modules (FAMs) are introduced in the encoder to extract frequency cues, effectively distinguishing low-contrast roads from the background. …”
Get full text

Using Large Language Models to Retrieve Critical Data from Clinical Processes and Business Rules by Yunguo Yu, Cesar A. Gomez-Cabello, Svetlana Makarova, Yogesh Parte, Sahar Borna, Syed Ali Haider, Ariana Genovese, Srinivasagam Prabha, Antonio J. Forte

“…We tested LLaMA 2′s performance in interpreting complex clinical process models, such as Mayo Clinic Care Pathway Models (CPMs), and providing accurate clinical recommendations. LLM was trained on encoded pathways versions using DOT language, embedding them with SentenceTransformer, and then presented with hypothetical patient cases. …”
Get full text

Enabling Cognitive Load-Aware AR with Rateless Coding on a Wearable Network by R. Razavi, M. Fleury, M. Ghanbari

“…Rateless coding is proposed to not only protect the fragile encoded video stream from wireless noise and interference but also to reduce coding overhead. …”
Get full text