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1061
An Indian Case Study on Mitochondrial Neurogastrointestinal Encephalomyopathy
Published 2024-05-01“…Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) is a unique autosomal recessive disorder characterized by mitochondrial changes resulting from mutations in the TYMP gene, responsible for encoding thymidine phosphorylase. Despite its genetic origin, the study indicates that the manifestation of MNGIE does not strictly adhere to a hereditary pattern. …”
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1062
GENES DETERMINING COLORATION OF DIFFERENT ORGANS IN WHEAT
Published 2014-12-01“…The data on comparative mapping together with the results of recent studies dedicated to cloning and functions of genes determining coloration in wheat suggest that these genes belong to the Myb- and Myc-like families of genes, encoding transcriptional activators for structural genes involved in plant flavonoid pigments biosynthesis.…”
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1063
Designing an innovative closed-loop supply chain network considering economic and environmental aspects
Published 2023-09-01“…For this purpose, a priority-based encoding is presented, and the Pareto front resulting from solving different problems is compared. …”
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1064
Phénomènes d’accommodation inter-sujets : le cas des reformulations introduites par OR
Published 2018-06-01“…Communication, whether it is written or oral, cannot be considered as the decoding, by the addressee(s), of messages that have simply been encoded by the speaker. Several factors constitute obstacles and prevent us from adopting such a basic pattern, such as the fact that representations are rarely shared by the speakers, that the latter sometimes use different language registers, and that speech also frequently contains mistakes or lacks adequacy with what the speaker really wants to say. …”
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1065
CYP2A6 Polymorphisms May Strengthen Individualized Treatment for Nicotine Dependence
Published 2015-01-01“…The normal nicotine metabolizer CYP2A6*1A is associated with high scores of nicotine dependence (5–10) on the Fagerström Test for Nicotine Dependence (FTND) scale because it encodes for enzymes that catalyze nicotine 100%. Slow nicotine metabolizers (i.e., CYP2A6*1H, CYP2A6*4A, CYP2A6*9, and CYP2A6*12A) are associated with underrated nicotine metabolizing activity (50%–75%), linking them to low scores for nicotine dependence (0–4) on the FTND scale. …”
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1066
Symmetry protected topological phases under decoherence
Published 2025-01-01“…The type-II strange correlator encodes the full topological response of the decohered mixed state, reflecting the SPT state's pre-decoherence presence. …”
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1067
Learning predictive signatures of HLA type from T-cell repertoires.
Published 2025-01-01“…T cells recognize a wide range of pathogens using surface receptors that interact directly with peptides presented on major histocompatibility complexes (MHC) encoded by the HLA loci in humans. Understanding the association between T cell receptors (TCR) and HLA alleles is an important step towards predicting TCR-antigen specificity from sequences. …”
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1068
Illuminating understudied kinases: a generalizable biosensor development method applied to protein kinase N
Published 2025-01-01“…Abstract Protein kinases play crucial roles in regulating cellular processes, making real-time visualization of their activity essential for understanding signaling dynamics. While genetically encoded fluorescent biosensors have emerged as powerful tools for studying kinase activity, their development for many kinases remains challenging due to the lack of suitable substrate peptides. …”
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1069
When HSFs bring the heat—mapping the transcriptional circuitries of HSF-type regulators in Candida albicans
Published 2025-01-01“…The genome of the opportunistic yeast Candida albicans encodes four HSF members, namely, Sfl1, Sfl2, Skn7, and the essential regulator, Hsf1. …”
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1070
Pharmacological approaches in drug-resistant pediatric epilepsies caused by pathogenic variants in potassium channel genes
Published 2025-01-01“…Variants in genes encoding for voltage-gated K+ (Kv) channels are frequent cause of drug-resistant pediatric epilepsies. …”
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1071
Quantifying the spatial patterns of retinal ganglion cell loss and progression in optic neuropathy by applying a deep learning variational autoencoder approach to optical coherence...
Published 2025-02-01“…The encoder decomposes input ganglion cell layer (GCL) thickness maps into two display latent variables (dLVs) and eight booster latent variables (bLVs). …”
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1072
Pan-cancer analysis of the transcriptional expression of histone acetylation enzymes in solid tumors defines a new classification scheme for gliomas
Published 2025-01-01“…IntroductionThe altered expression of genes encoding histone acetyltransferases (HATs) and histone deacetylases (HDACs) has been implicated in the tumorigenesis and progression of various solid tumors. …”
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1073
Single Dose of Attenuated Vaccinia Viruses Expressing H5 Hemagglutinin Affords Rapid and Long-Term Protection Against Lethal Infection with Highly Pathogenic Avian Influenza A H5N1...
Published 2025-01-01“…Results: rLC16m8-mcl2.2 hemagglutinin (HA) and rLC16m8-mcl2.3.4 HA consisted of a recombinant LC16m8 vector encoding the HA protein from clade 2.2 or clade 2.3.4 viruses (respectively); rDIs-mcl2.2 HA consisted of a recombinant DIs vector encoding the HA protein from clade 2.2. …”
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1074
From structure prediction to function: defining the domain on the African swine fever virus CD2v protein required for binding to erythrocytes
Published 2025-02-01“…This large DNA virus encodes more than 150 open reading frames, many of which are uncharacterized. …”
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1075
Analisis Perbandingan Model Bert Dan Xlnet Untuk Klasifikasi Tweet Bully Pada Twitter
Published 2024-12-01“…Penelitian ini bertujuan untuk membandingkan performa dua model pemrosesan bahasa alami terbaru, yaitu BERT (Bidirectional Encoder Representations from Transformers) dan XLNet, dalam klasifikasi tweet yang mengandung bullying. …”
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1076
Feasibility of Muscle Synergy Outcomes in Clinics, Robotics, and Sports: A Systematic Review
Published 2018-01-01“…Even though the neural encoding of muscle synergies remains controversial, a large number of papers demonstrated that muscle synergies are robust across different tested conditions, which are within a day, between days, within a single subject, and between subjects that have similar demographic characteristics. …”
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1077
Growth on Alpha-Ketoglutarate Increases Oxidative Stress Resistance in the Yeast Saccharomyces cerevisiae
Published 2017-01-01“…The presence of genes encoding SODs or catalases is required for the expression of protective effects of AKG.…”
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1078
The evolutionarily diverged single-stranded DNA-binding proteins SSB1/SSB2 differentially affect the replication, recombination and mutation of organellar genomes in Arabidopsis th...
Published 2025-01-01“…In Arabidopsis thaliana, SSBs are encoded by a small family of two genes (SSB1 and SSB2). …”
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1079
SOST and DKK: Antagonists of LRP Family Signaling as Targets for Treating Bone Disease
Published 2010-01-01“…Point mutations were identified that encoded forms of LRP5 associated with very high bone mass (HBM). …”
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1080
PROJECT MANAGEMENT PRACTICES AND PROJECTS SUCCESS AMONG DEVELOPING ECONOMIES– AN EGYPTIAN COMPARATIVE STUDY
Published 2024-09-01“…Data on 537 engineers, project managers, and administrators was collected, encoded, and assessed. Nonparametric tests and descriptive have been utilised to characterise the sample, evaluate hypotheses, and address the enquiries. …”
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