Nuclear-Targeting Delivery of CRISPRa System for Upregulation of β-Defensin against Virus Infection by Dexamethasone and Phenylalanine Dual-Modified Dendrimer by Mingxiang Zuo, Xiaoxia Li, Shuang Liu, Bin Chen, Du Cheng

“…The dual-modified dendrimer containing dexamethasone (DET) and phenylalanine (Phe) was prepared to deliver plasmid DNA encoding dCas9 and single-guide RNA (sgRNA) for specific upregulation of β-defensin. …”
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DYNAMICS OF IL12 CYTOKINE EXPRESSION IN HUMAN MACROPHAGES AFTER TREATMENT WITH DIOXIN by D. Y. Oshchepkov, E. V. Kashina, E. V. Antontseva, E. A. Oshchepkova, V. A. Mordvinov, D. P. Furman

“…Thus, the well-known dioxin influence on the immune system can be associated with the difference in the dioxin effect on the expression dynamics of the genes encoding IL-12 subunits.…”
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Capsular polysaccarides of probiotics and their immunomodulatory roles by Jing Li, Saisai Feng, Leilei Yu, Jianxin Zhao, Fengwei Tian, Wei Chen, Qixiao Zhai

“…The genes known to be associated with these two pathways are mainly those associated with priming glycosyltransferase (pGT); a variable number of genes encoding for different glycosyl transferases (GTs); Wzx/Wzy-encoding enzymes related to flippases and polymerases; and ABC-transporter genes. …”
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Tuning a SAM-Based Model With Multicognitive Visual Adapter to Remote Sensing Instance Segmentation by Linghao Zheng, Xinyang Pu, Su Zhang, Feng Xu

“…The SAM-multicognitive visual adapter (Mona) encoder utilizing the Mona is conducted to facilitate SAM's transfer learning in remote sensing applications. …”
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FFUNet: A novel feature fusion makes strong decoder for medical image segmentation by Junsong Xie, Renju Zhu, Zezhi Wu, Jinling Ouyang

“…On the other hand, the feature gap between an encoder and decoder is also challenging for a U‐shaped network, which adopts a plain skip connection. …”
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Molecular logic for cellular specializations that initiate the auditory parallel processing pathways by Junzhan Jing, Ming Hu, Tenzin Ngodup, Qianqian Ma, Shu-Ning Natalie Lau, M. Cecilia Ljungberg, Matthew J. McGinley, Laurence O. Trussell, Xiaolong Jiang

“…In particular, CN cell-type identity is encoded in a transcriptional architecture that orchestrates functionally congruent expression across a small set of gene families to customize projection patterns, input-output synaptic communication, and biophysical features required for encoding distinct aspects of acoustic signals. …”
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Complex-Valued CNN Nonlinear Equalization Enabled 36-Tbit/s (45×800-Gbit/s) WDM Transmission Over 3150 Km Using Silicon-Based IC-TROSA by Yuhan Gong, Xiaoshuo Jia, Ying Zhu, Kailai Liu, Ming Luo, Jin Tao, Zhixue He, Chao Li, Zichen Liu, Yan Li, Jian Wu, Chao Yang

“…This algorithm exhibits different equalization performances for 64QAM signals under various encoding schemes considering 20%-overhead, achieving up to 2dB maximum decrease in the required optical signal-to-noise ratio at the optical back-to-back case. …”
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Neural decoding reveals dynamic patterns of visual chunk memory processes by Chantat Leong, Fei Gao, Zhen Yuan

“…In the decision-making stage, chunk memory processes were encoded by four ERP components. Scene processing correlated with P1, followed by feature extraction facilitated by P2, encoding process (P4), and segmentation process (P6). …”
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Modelling Hysteresis in Shape Memory Alloys Using LSTM Recurrent Neural Network by Mohammad Reza Zakerzadeh, Seyedkeivan Naseri, Payam Naseri

“…In the online configuration where the model uses encoder data as angular inputs, the root mean square error (RMSE) of predictions for various input voltages is significantly low at about 0.1 degrees where the maximum rotational angle of pulley is 8 degrees. …”
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Discrimination of Radiologists' Experience Level Using Eye-Tracking Technology and Machine Learning: Case Study by Stanford Martinez, Carolina Ramirez-Tamayo, Syed Hasib Akhter Faruqui, Kal Clark, Adel Alaeddini, Nicholas Czarnek, Aarushi Aggarwal, Sahra Emamzadeh, Jeffrey R Mock, Edward J Golob

“…The encoded features of the eye-fixation data are used by machine learning classifiers to discriminate between faculty and trainee radiologists. …”
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Grammar-constrained decoding for structured information extraction with fine-tuned generative models applied to clinical trial abstracts by David M. Schmidt, Philipp Cimiano

“…These constraints, however, can typically not be guaranteed using standard (fine-tuned) encoder-decoder architectures. This has led to the development of constrained decoding approaches which allow, e.g., to specify constraints in form of context-free grammars. …”
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Bubbling insights: unveiling the true sophorolipid biosynthetic pathway by Starmerella bombicola by Sophie L. K. W. Roelants, Stijn Bovijn, Elvira Bytyqi, Nicolas de Fooz, Goedele Luyten, Martijn Castelein, Thibo Van de Craen, Zhoujian Diao, Karolien Maes, Tom Delmulle, Maarten De Mol, Sofie L. De Maeseneire, Bart Devreese, Wim K. Soetaert

“…Results Recently, Starmerella bombicola strains developed and evaluated in the past were reevaluated unveiling unexpected findings. The AT enzyme encoded in the sophorolipid biosynthetic gene cluster is the only described enzyme known to acetylate sophorolipids, while the SBLE enzyme encoded by the SBLE gene is described to catalyze the conversion of (acetylated) acidic sophorolipids into lactonic sophorolipids. …”
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First VIM-producing representative of Pseudomonas putida group from the largest Bulgarian hospital by Atanaska Petrova, Ivan N. Ivanov, Liubomir Paunov, Angel Uchikov, Ivan Stoikov, Todor Kantardjiev, Marianna Murdjeva

“…Multiplex PCR was performed to search for nine common carbapenemase encoding genes whereas the variable region of the integron was determined by DNA sequencing. …”
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Leveraging Segment Anything Model (SAM) for Weld Defect Detection in Industrial Ultrasonic B-Scan Images by Amir-M. Naddaf-Sh, Vinay S. Baburao, Hassan Zargarzadeh

“…As part of designing a practical AI-assistant tool, the experiments involve applying both vanilla and low-rank adaptation (LoRA) fine-tuning techniques to the image encoder and mask decoder of different variants of both models, while keeping the prompt encoder unchanged. …”
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Utilizing physiologies, transcriptomics, and metabolomics to unravel key genes and metabolites of Salvia miltiorrhiza Bge. seedlings in response to drought stress by Yu Zhang, Hong Zhang, Yuru Zhang, Di Wang, Xue Meng, Juan Chen

“…Transcriptome analyses revealed 383 genes encoding transcription factors and 80 genes encoding plant hormones as hypothetical regulators of drought resistance in S. miltiorrhiza plants. …”
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Quantum Computation via Multiport Discretized Quantum Fourier Optical Processors by Mohammad Rezai, Jawad A. Salehi

“…Due to various advantages of the proposed scheme, including the large information capacity of the photon wavefront, a quadratically reduced number of optical resources compared with other conventional path-encoding techniques, and dynamic programmability, the proposed scheme has the potential to be an essential contribution to linear optical quantum computing and optical quantum signal processing.…”
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Semantic-enhanced panoptic scene graph generation through hybrid and axial attentions by Xinhe Kuang, Yuxin Che, Huiyan Han, Yimin Liu

“…Specifically, a series of hybrid attention networks are stacked within both the object context encoding and relationship context encoding modules, enhancing the refinement and fusion of visual and semantic information. …”
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Physiological analysis of cognitive load variations during complex information processing by Allan Armougum, Alexandre Gaston-Bellegarde, Chantal Joie-La Marle, Pascale Piolino

“…With rise in expertise of the investigated train station, participants showed equal or higher cognitive load than participants with lower expertise level, from encoding to recognition phase of the experiment, suggesting an expertise reversal effect. …”
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Therapeutic Metaphors Enhance Memory Systems in Mental Health Contexts by Fei Yu, Zhijie Zhang, Wencai Zhang

“…Methods At first, 31 participants read a mental distress problem, followed by a metaphorical or a literal solution, while undergoing functional magnetic resonance imaging scanning during the encoding phase. One week later, a recognition memory test was performed outside the scanner. …”
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The Development of Microhistorical Databases in Norway. A Historiography by Gunnar Thorvaldsen, Lars Holden

“…Today, most census and ministerial records from 1801 until the mid-20th century have been scanned, transcriptions are being completed, much is encoded and made available via the websites of the Digital National Archives and UiT The Arctic University of Norway. …”
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