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641
Temporal response patterns of Layer 4 rat barrel cortex neurons across various naturalistic whisker motions.
Published 2024-01-01“…Despite significant advancements in this area, the characterisation of information encoding through the precise timing of spikes in the somatosensory cortex is limited. …”
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642
Offline prompt reinforcement learning method based on feature extraction
Published 2025-01-01“…By sampling the specific information in the offline dataset as trajectory samples, the task information is encoded to help the pre-trained model quickly understand the task characteristics and the sequence generation paradigm to quickly adapt to the downstream tasks. …”
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643
Novel Chemokine-Based Immunotoxins for Potent and Selective Targeting of Cytomegalovirus Infected Cells
Published 2017-01-01“…One recent example targeted the virus-encoded G protein-coupled receptor US28 as a strategy for specific and efficient treatment of human cytomegalovirus (HCMV) infections. …”
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644
Quantum distance approximation for persistence diagrams
Published 2025-01-01“…Our implementation is a weighted version of the quantum approximate optimization Algorithm that relies on control clauses to encode the constraints of the optimization problem.…”
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645
Encapsulation and Melanization Are Not Correlated to Successful Immune Defense Against Parasitoid Wasps in <i>Drosophila melanogaster</i>
Published 2025-01-01“…Expression profiles of the <i>PPO2</i> and <i>PPO3</i> prophenoloxidase genes, which encode key enzymes in the melanization reaction, were detected by qRT-PCR. …”
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646
CryJ-LAMP DNA Vaccines for Japanese Red Cedar Allergy Induce Robust Th1-Type Immune Responses in Murine Model
Published 2016-01-01“…We utilized the lysosomal targeting property of lysosomal-associated membrane protein-1 (LAMP-1) to make DNA vaccines that encode LAMP-1 and the sequences of immunodominant allergen CryJ1 or CryJ2 from the JRC pollen. …”
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647
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648
PURE: a Prompt-based framework with dynamic Update mechanism for educational Relation Extraction
Published 2024-12-01“…This framework embraces a prompt-tuning strategy and employs a more appropriate MacBERT-large model to encode the instances wrapped by prompt templates. …”
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649
Prediction of influenza A virus-human protein-protein interactions using XGBoost with continuous and discontinuous amino acids information
Published 2025-01-01“…Then we used conjoint triad (CT) and Moran autocorrelation (Moran) to encode biologically relevant features. The joint consideration utilizing the complementary information between contiguous and discontinuous amino acids provides a more comprehensive description of PPI information. …”
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650
Sequence Analysis of Hypothetical Proteins from 26695 to Identify Potential Virulence Factors
Published 2016-09-01“…The genome of H. pylori 26695 strain contains 1,555 coding genes that encode 1,445 proteins. Out of these, 340 proteins are characterized as hypothetical proteins (HP). …”
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651
The design of experiments for the transcriptome studies by high-throughput sequencing methods
Published 2016-05-01“…The common questions in the design of the highthroughput sequencing experiments using RNA-Seq or Ribo-Seq methods are reviewed. The ENCODE guidelines (2011) as well as the recently published advances in the design of the studies of mammalian, animal and plant transcriptomes are also summarized in this review. …”
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652
A Constitutively Mannose-Sensitive Agglutinating Salmonella enterica subsp. enterica Serovar Typhimurium Strain, Carrying a Transposon in the Fimbrial Usher Gene stbC, Exhibits Mul...
Published 2012-01-01“…A transposon inserted in stbC, which would encode an usher for Stb fimbriae of a non-flagellar Salmonella enterica subsp. enterica serovar Typhimurium LB5010 strain, conferred it to agglutinate yeast cells on both cultures. …”
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653
Fungal genomes: suffering with functional annotation errors
Published 2021-11-01“…However, InterproScan analysis indicated that none of the protein sequences annotated as “calcium dependent protein kinase” were found to encode calcium binding EF-hands at the regulatory domain. …”
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654
Small open reading frames (sORFs): Driving big improvements in plant development and quality
Published 2025-03-01“…Small open reading frames (sORFs) are defined as short nucleotide sequences, typically no longer than 300 base pairs, which have the potential to encode small peptides. With the advent of sophisticated technologies such as bioinformatics, ribosome profiling, and mass spectrometry, the investigation of sORFs has experienced a transformative shift and significant expansion. …”
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655
Genome-Wide Identification and Expression Analysis of the <i>ALDH</i> Gene Family in <i>Sinonovacula constricta</i> Bivalve in Response to Acute Hypersaline Stress
Published 2024-12-01“…These genes are located on eight chromosomes, with tandem duplications observed on chromosome 10; they encode mostly acidic and hydrophilic proteins. Among them, <i>ScALDH18A1</i> contains a conserved P5CS domain that is implicated in proline synthesis and osmotic regulation. …”
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656
Spontaneously Diabetic Torii (SDT) Fatty Rat, a Novel Animal Model of Type 2 Diabetes Mellitus, Shows Blunted Circadian Rhythms and Melatonin Secretion
Published 2018-01-01“…To get an insight into the mechanism underlying the impaired melatonin secretion in SDT fatty rats, the expression of arylalkylamine N-acetyltransferase (Aanat) and acetylserotonin O-methyltransferase (Asmt) mRNA, which encode the rate-limiting enzymes for melatonin synthesis, was investigated in the pineal gland. …”
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657
Unexpected inheritance: multiple integrations of ancient bornavirus and ebolavirus/marburgvirus sequences in vertebrate genomes.
Published 2010-07-01“…The integrations represent genes that encode viral nucleocapsid, RNA-dependent-RNA-polymerase, matrix and, possibly, glycoproteins. …”
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658
Expanding the Diversity of <i>Actinobacterial Tectiviridae</i>: A Novel Genus from <i>Microbacterium</i>
Published 2025-01-01“…Like other <i>Tectiviridae</i>, the phage genomes are arranged into two segments and include three highly conserved family genes that encode a DNA polymerase, double jelly-roll major capsid protein, and packaging ATPase. …”
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659
Comparing Effects of BK Virus Agnoprotein and Herpes Simplex-1 ICP47 on MHC-I and MHC-II Expression
Published 2013-01-01“…Among human polyomaviruses, only BK virus (BKV) and JC virus (JCV) encode an agnoprotein upstream of VP1 on the viral late transcript. …”
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660
Impact of glycolysis inhibitor (2-DG) and oxidation and phosphorylation uncoupler (2,4-DNP) on brain metabolites
Published 2018-04-01“…A deficiency of available energy for brain cells under neurodegenerative diseases is either developed due to age-dependent underexpression of genes that encode glycolytic enzymes or induced due to the uncoupling of oxidation and phosphorylation that could be mediated by inflammatory cytokines. …”
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