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2901
Contrastive learning with transformer for adverse endpoint prediction in patients on DAPT post-coronary stent implantation
Published 2025-01-01“…Our approach first utilized an auto-encoder to compress patient features into a more manageable, condensed representation. …”
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2902
Emerging Resistance and Virulence Patterns in <i>Salmonella enterica</i>: Insights into Silver Nanoparticles as an Antimicrobial Strategy
Published 2025-01-01“…Resistance to trimethoprim-sulfamethoxazole was encoded by the <i>sul1</i> gene in 44.83% of the strains and to tetracyclines by the <i>tet(A)</i> gene (59.52%). …”
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2903
PGC-1α Promotes mitochondrial biosynthesis and energy metabolism of goose fatty liver
Published 2025-01-01“…The abundance of mitochondrial biosynthesis-related and energy metabolism-related genes, including mitochondrial transcription factor A (TFAM), mitochondrial transcription factor B1 (TFB1M), mitochondrial transcription factor B2 (TFB2M), nuclear respiratory factor 1 (NRF1), DNA topoisomerase I mitochondrial (TOP1MT), peroxisome proliferator-activated receptor gamma coactivator 1-beta (PGC-1β), sirtuin 3 (SIRT3), mitochondrially encoded cytochrome B (CYTB), and AMP-activated protein kinase alpha (AMPKα) were significantly increased in fatty liver. …”
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2904
Molecular mechanisms impact on fluoroquinolone resistance among E.coli from enteric carriage monitoring before prostate biopsy and earliest description of qnrB81
Published 2024-11-01“…Based on the MICs range of Qs (24–256 mg/L) and FQs (0.24–128 mg/L) breakpoint by EUCAST, we categorized these E. coli isolates into three resistance profiles (I, II, and III) associated with the patterns of chromosomal mutations in the quinolone resistance-determining regions (QRDRs) of gyrA and parC and the plasmid-mediated quinolone resistance encoding genes (PMQRs) detected by PCR-based assay and sequencing; MICs increase in an escalation step according to the co-occurrence of multiple molecular mechanisms. …”
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2905
Structure and Expression of Two Sex-Related dmrt Genes in Oxyeleotris lineolata
Published 2025-02-01“…The open reading frame (ORF) of Oxldmrt1 and Oxldmrt3 were 903 bp and 1 363 bp, encoding 300 and 453 amino acids, respectively. OxlDMRT1 belongs to basic proteins, whereas OxlDMRT3 belongs to acidic proteins. …”
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2906
Detection of cervical precancerous lesions and cancer by small-scale RT-qPCR analysis of oppositely deregulated mRNAs pairs in cytological smears
Published 2025-01-01“…Various molecular biomarkers are proposed in recent years to improve cervical cancer management, including a number of mRNAs encoded by human genes involved in carcinogenesis. …”
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2907
Exome sequencing reveals a rare damaging variant in GRIN2C in familial late-onset Alzheimer's disease
Published 2025-01-01“…(A1072V) variant in GRIN2C gene (NM 000835.6), encoding for the glutamate ionotropic receptor N-methyl-D-aspartate receptor (NMDA) type subunit 2C (GluN2C). …”
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2908
Biliary atresia susceptibility gene EFEMP1 regulates extrahepatic bile duct elastic fiber formation and mechanics
Published 2025-01-01“…Impact and implications:: The gene EFEMP1 was found via a genome-wide association study to be a susceptibility gene for the neonatal disease biliary atresia. EFEMP1 encodes the protein fibulin-3, which regulates elastic fiber organization in the extrahepatic bile duct (EHBD), the major site of disease in biliary atresia. …”
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2909
Generation of novel oncolytic vaccinia virus with improved intravenous efficacy through protection against complement-mediated lysis and evasion of neutralization by vaccinia virus...
Published 2023-01-01“…The viral thymidine kinase (J2R) gene was replaced by genes encoding the CD55 fusion proteins and GM-CSF.Results SJ-600 series viruses expressing human CD55 on the IMV membrane showed resistance to serum virus neutralization. …”
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2910
Genome-wide association mapping and genomic prediction analyses reveal the genetic architecture of grain yield and agronomic traits under drought and optimum conditions in maize
Published 2025-02-01“…Two major candidate genes, Zm00001eb041070 closely associated with grain yield near peak QTN, qGY_DS1.1 (S1_216149215) and Zm00001eb364110 closely related to anthesis-silking interval near peak QTN, qASI_DS8.2 (S8_167256316) were identified, encoding AP2-EREBP transcription factor 60 and TCP-transcription factor 20, respectively under drought stress. …”
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2911
Prevalence and Molecular Characterization of Carbapenemase-Producing Multidrug-Resistant Bacteria in Diabetic Foot Ulcer Infections
Published 2025-01-01“…A total of 200 clinical isolates from DFU patients were analyzed via phenotypic assays, including the modified Hodge test (MHT) and the Carba NP test, alongside molecular techniques to detect carbapenemase-encoding genes (<i>blaKPC</i>, <i>blaNDM</i>, <i>blaVIM</i>, <i>blaIMP</i>, and <i>blaOXA-48</i>). …”
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2912
Exploring the role of ESR1 mutations in metastatic hormone receptor-positive breast cancer T cell immune surveillance disruption
Published 2025-02-01“…In 40% of cases, a key mechanism of endocrine resistance to the standard first line is a mutation of the ligand-binding domain (LBD) of Estrogen Receptor 1 (ESR1) encoding estrogen receptor α (ER). Most common ESR1 mutations that occur at positions 537 and 538 have been associated with poor clinical outcomes. …”
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2913
A novel Alteromonas phage with tail fiber containing six potential iron-binding domains
Published 2025-01-01“…Two auxiliary metabolic genes, encoding Acyl carrier protein and AAA domain-containing protein, were predicted in R22Y, which may potentially assist in host fatty acid metabolism and VB12 biosynthesis, respectively. …”
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2914
Diversity and Complexity of CTXΦ and Pre-CTXΦ Families in <em>Vibrio cholerae</em> from Seventh Pandemic
Published 2024-09-01“…CTXΦ is a lysogenic filamentous phage that carries the genes encoding cholera toxin (<i>ctxAB</i>), the main virulence factor of <i>Vibrio cholerae</i>. …”
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2915
Mitochondrial targeting of Candida albicans SPFH proteins and requirement of stomatins for SDS-induced stress tolerance
Published 2025-01-01“…Mitochondria are essential for C. albicans commensalism and virulence, and mitochondrial proteins are targets for antifungal interventions. C. albicans encodes five SPFH proteins: two stomatin-like proteins and three prohibitins. …”
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2916
Keamanan Data Menggunakan Secure Hashing Algorithm (SHA)-256 dan Rivest Shamir Adleman (RSA) pada Digital Signature
Published 2023-12-01“…To prevent letter forgery, data integrity, and data validity, the contents of protected documents are encoded using the SHA-256 and RSA cryptographic algorithms. …”
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2917
Production and bioactivity test of recombinant protein common carp growth hormone
Published 2011-01-01“… This study aimed to produce recombinant growth hormone (rGH) protein of common carp (Cyprinus carpio) and evaluate its bioactivity. DNA fragment encoding mature GH protein of common carp (mCcGH) was amplified by polymerase chain reaction (PCR) method and PCR products were then ligated into pCold I to generate pCold I-mCcGH protein expression vector. …”
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2918
A KSHV RNA-binding protein promotes FOS to inhibit nuclease AEN and transactivate RGS2 for AKT phosphorylation
Published 2025-01-01“…ABSTRACT Kaposi’s sarcoma-associated herpesvirus (KSHV) encodes an RNA-binding protein ORF57 in lytic infection. …”
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2919
Intelligent task-oriented semantic communications:theory, technology and challenges
Published 2022-06-01“…Furthermore, from the perspective of neural network interpretability,an interpretability-based semantic encoding method is proposed.Finally, a semantic communication platform for intelligent tasks is built based on software and hardware such as USRP and LabView,and the performance of the proposed algorithm is verified. …”
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2920
Artemia sp. as a DNA vaccine vector for common carp Cyprinus carpio larvae
Published 2014-01-01“…This experiment was carried out by analysis DNA vaccine expression encoding of glycoprotein gene (GP-11) on C. carpio. …”
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