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2361
Characterizing the regulatory effects of H2A.Z and SWR1-C on gene expression during hydroxyurea exposure in Saccharomyces cerevisiae.
Published 2025-01-01“…Chromatin structure and DNA accessibility are partly modulated by the incorporation of histone variants. H2A.Z, encoded by the non-essential HTZ1 gene in S. cerevisiae, is an evolutionarily conserved H2A histone variant that is predominantly incorporated at transcription start sites by the SWR1-complex (SWR1-C). …”
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2362
Efficient Anomaly Detection Algorithm for Heart Sound Signal
Published 2024-01-01“…Firstly, we enhance the ability to extract local texture features of heart sound signals by introducing a convolutional embedding module into the positional encoding layer of the backbone network. Second, we augmented the model’s capability to extract the frequency-domain features of heart-sound signals by incorporating a discrete convolutional mapping structure. …”
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2363
Rhipicephalus simus ticks: new hosts for phleboviruses
Published 2024-08-01“…Its RNA-dependent RNA polymerase (RdRp) encoding region carried conserved RdRp and endonuclease domains characteristic of phenuiviridae viruses. …”
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2364
An In silico Approach towards Finding the Cancer-Causing Mutations in Human MET Gene
Published 2023-01-01“…Mesenchymal–epithelial transition (MET) factor is a proto-oncogene encoding tyrosine kinase receptor with hepatocyte growth factor (HGF) or scatter factor (SF). …”
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2365
Heterologous Expression of Laccase1 from Cryphonectria parasitica in Saccharomyces cerevisiae
Published 2025-01-01“…To obtain high and stable expression of fungal laccases, we cloned the gene encoding an extracellular laccase (Laccase1) of C. parasitica into a yeast episomal vector, used the resulting vectors to transform S. cerevisiae, and optimized the culture conditions of the selected transformants for Laccase1 production. …”
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2366
Chromatin remodeling (SWI/SNF) complexes, cancer, and response to immunotherapy
Published 2022-09-01“…Significantly, ~20% of malignancies harbor alterations in >1 of these subunits, making the genes encoding SWI/SNF family members among the most vulnerable to genomic aberrations in cancer. …”
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2367
The IclR-family transcriptional regulator XyrR controls flotation, motility, antibiotic production and virulence in Serratia sp. ATCC 39006
Published 2025-01-01“…We also found that the proteins encoded by a putative yagEF-yjhF operon, involved in xylonate catabolism and transport, showed a 5- to 7-fold increase in expression. …”
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2368
AFN-Net: Adaptive Fusion Nucleus Segmentation Network Based on Multi-Level U-Net
Published 2025-01-01“…Firstly, we introduce a Weighted Feature Enhancement Unit (WFEU) in the encoder decoder fusion stage of U-Net. By assigning learnable weights to different feature maps, the network can adaptively enhance key features and suppress irrelevant or secondary features, thus maintaining high-precision segmentation performance in complex backgrounds. …”
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2369
Vehicle Detection Algorithm Based on Embedded Video Image Processing in the Background of Information Technology
Published 2022-01-01“…The primary problem in embedding digital video in applications is that the complexity of video encoding and decoding far exceeds that of simple image and audio compression and decompression. …”
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2370
First International Conference on Lysophospholipids and Related Bioactive Lipids in Biology and Disease Sponsored by the Federation of American Societies of Experimental Biology
Published 2001-01-01“…The receptor subfamilies formerly were designated endothelial differentiation gene-encoded receptors or Edg Rs for their original discovery in endothelial cells. …”
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2371
Operational Deflection Shape Extraction from Broadband Events of an Aircraft Component Using 3D-DIC in Magnified Images
Published 2019-01-01“…Moreover, phase-based motion magnification (PMM) is a methodology which, based on a sequence of images, magnifies a periodic motion encoded in phase time-domain signals of the complex steerable pyramid filters employed to decompose the images. …”
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2372
Speech Emotion Recognition Model Based on Joint Modeling of Discrete and Dimensional Emotion Representation
Published 2025-01-01“…The architecture employs parallel feature extraction through independent encoders, designed to capture unique features from multiple modalities, including Mel-frequency Cepstral Coefficients (MFCC), Short-term Features (STF), Mel-spectrograms, and raw audio signals. …”
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2373
Toxin and capsule production by Bacillus cereus biovar anthracis influence pathogenicity in macrophages and animal models.
Published 2024-12-01“…Genomic analyses revealed Bcbva as a member of the B. cereus species that carries two plasmids, pBCXO1 and pBCXO2, which have high sequence homology to the B. anthracis toxin and polyglutamate capsule encoding plasmids pXO1 and pXO2, respectively. To date, only a few studies have investigated the effect of variations in Bcbva sporulation, toxin, and capsule synthesis on animal and macrophage pathogenicity compared to B. anthracis, therefore more research is needed to gain a better understanding of the pathogenesis of this emerging infection. …”
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2374
Immunopathology of Airway Surface Liquid Dehydration Disease
Published 2019-01-01“…As an alternative, the Scnn1b transgenic (Scnn1b-Tg+) mouse model overexpressing a transgene encoding sodium channel nonvoltage-gated 1, beta subunit (Scnn1b) in airway club cells is available. …”
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2375
CSE-8, a filamentous fungus-specific Shr3-like chaperone, facilitates endoplasmic reticulum exit of chitin synthase CHS-3 (class I) in Neurospora crassa
Published 2025-01-01“…The Neurospora crassa genome encodes two orthologues of Chs7: chitin synthase export (CSE) proteins CSE-7 (NCU05720) and CSE-8 (NCU01814), both of which are highly conserved among filamentous fungi. …”
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2376
Primary Signet Ring Cell/Histiocytoid Carcinoma of the Eyelid: Clinicopathologic Analysis with Evaluation of the E-Cadherin/β-Catenin Complex and Associated Genetic Alterations
Published 2021-01-01“…The CDH1 gene, which encodes the E-cadherin protein, is the best known gene associated with these tumors. …”
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2377
Online resources on gene networks containing human and animal data
Published 2018-01-01“…Gene networks are molecular genetic systems that ensure the formation of phenotypic characteristics of organisms (molecular, biochemical, structural, morphological, behavioral, etc.) based on information encoded in their genomes. Reconstruction of gene networks provides a methodological basis for modern systems biology. …”
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2378
KAI2-dependent signaling controls vegetative reproduction in Marchantia polymorpha through activation of LOG-mediated cytokinin synthesis (14)
Published 2025-02-01“…We find that KAI2-dependent signaling positively controls the expression of MpLONELY GUY (MpLOG), encoding a cytokinin biosynthesis enzyme. Disruption of the MpLOG function decreases endogenous cytokinin levels and causes defects similar to KAI2-dependent signaling mutants. …”
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2379
Exploring the Credibility of Large Language Models for Mental Health Support: Protocol for a Scoping Review
Published 2025-01-01“… BackgroundThe rapid evolution of large language models (LLMs), such as Bidirectional Encoder Representations from Transformers (BERT; Google) and GPT (OpenAI), has introduced significant advancements in natural language processing. …”
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2380
Significant abundance of bacterial flagellin and expression of its surface localized receptor toll-like receptor 5 and cytokine interleukin-22 in South African infants with poor or...
Published 2025-01-01“…The abundance of flagellin and expression of flagellin-encoding fliC, TLR5 and NLRC4, IL-22 and IL-18 genes was determined by qPCR. …”
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