Enhanced Heart Disease Classification Using Dual Attention Mechanisms and 3D-Echo Fusion Algorithm in Echocardiogram Videos by S Deepika, N. Jaisankar

“…Our method employs a CNN-based encoder to extract spatial features from individual video frames, which are then enhanced through a 3D-Echo Fusion technique to capture comprehensive volumetric information. …”
Get full text

Utility of Lymphoblastoid Cell Lines for Induced Pluripotent Stem Cell Generation by Satish Kumar, Joanne E. Curran, David C. Glahn, John Blangero

“…Here, we report a new optimized LCL-to-iPSC reprogramming protocol using episomal plasmids encoding pluripotency transcription factors and mouse p53DD (p53 carboxy-terminal dominant-negative fragment) and commercially available reprogramming media. …”
Get full text

A sensitive ERK fluorescent probe reveals the significance of minimal EGF-induced transcription by Zhang Weisheng, Jun Nakayama, Yukino Inomata, Shigeki Higashiyama, Toru Hiratsuka

“…Extracellular signal-regulated kinase (ERK) regulates multiple cellular functions through distinct activation patterns. Genetically encoded fluorescent probes are instrumental in dissecting the ERK activity dynamics in living cells. …”
Get full text

Detection of OqxAB Efflux Pumps, a Multidrug-Resistant Agent in Bacterial Infection in Patients Referring to Teaching Hospitals in Ahvaz, Southwest of Iran by Mojtaba Moosavian, Mahtab Khoshkholgh Sima, Nazanin Ahmad Khosravi, Effat Abbasi Montazeri

“…In this study, we investigated the prevalence of oqxA and oqxB genes as two encoding agents of efflux pumps and the determination of antibiotic resistance rate in clinical isolates of Enterobacteriaceae. …”
Get full text

Transcription factor TCF4: structure, function, and associated diseases by R. R. Savchenko, N. A. Skryabin

“…This review focuses on the TCF4 gene that encodes a transcription factor crucial for nervous system development and functioning. …”
Get full text

Rabex-5 E3 and Rab5 GEF domains differ in their regulation of Ras, Notch, and PI3K signaling in Drosophila wing development. by Theresa A Reimels, Mia Steinberg, Hua Yan, Sivan Shahar, Ashley Rosenberg, Kristina Kalafsky, Max Luf, Lindsay Kelly, Stacia Octaviani, Cathie M Pfleger

“…Here we report genetic interactions using Rabex-5 transgenes encoding domain-specific mutations that show that Rabex-5 requires an intact E3 domain to inhibit Notch signaling in the epithelial tissue of the developing wing. …”
Get full text

Tension Recordings from Primary Bronchi in Acta2-GCaMP8.1-mVermilion Transgenic Mice by Qais Khalaf, Srijit Ghosh, Keith Thornbury

“…Transgenic Acta2-GCaMP8.1-mVermilion (GCaMP) mice express a genetically encoded intracellular fluorescent Ca2+ indicator in smooth muscle cells, have been developed to facilitate the study of Ca2+. …”
Get full text

Identification and validation of reference genes for quantitative gene expression analysis under 409 and 415 nm antimicrobial blue light treatment by Beata Kruszewska-Naczk, Mariusz Grinholc, Aleksandra Rapacka-Zdonczyk

“…Therefore, the purpose of the present study was to determine the most stable reference gene under treatment with aBL under sublethal conditions and to evaluate differences in the expression of the selected gene after aBL treatment in comparison to the nontreated control.MethodsSelection of stable reference genes was performed using 4 programs: BestKeeper, geNorm, NormFinder and RefFinder under 409 and 415 nm aBL treatment.ResultsThe results revealed that the gene encoding the integration host factor β subunit (ihfB) in Escherichia coli was the most stably expressed gene after both 409 and 415 nm aBL treatment. …”
Get full text

An efficient and lightweight detection method for stranded elastic needle defects in complex industrial environments using VEE-YOLO by Qiaoqiao Xiong, Qipeng Chen, Saihong Tang, Yiting Li

“…Secondly, improvements were made to the model’s feature extraction quality by encoding inter-channel information using efficient multi-Scale attention to consider channel importance. …”
Get full text

DIONYSUS CULT AS A PROTOTYPE OF AUTONOMOUS GENDER by O. O. Poliakova, V. V. Asotskyi

“…Specific sensory and mental qualities encoded in the images of Dionysian madness, vakhtnag of violence and the eternal alien, the awareness of which is determined by the Dionysian thematizes in the cultural consciousness of post-modernism, the research literature presented in fragments. …”
Get full text

Soil-Borne Microbial Functional Structure across Different Land Uses by Eiko E. Kuramae, Jizhong Z. Zhou, George A. Kowalchuk, Johannes A. van Veen

“…Fields with low C : N ratio had an overrepresentation of genes for carbon degradation, carbon fixation, metal reductase, and organic remediation categories, while fields with high C : N ratio had an overrepresentation of genes encoding dissimilatory sulfate reductase, methane oxidation, nitrification, and nitrogen fixation. …”
Get full text

The prevalence of multidrug resistance in Staphylococcus hominis isolated from clinical materials by Magdalena Szemraj, Paulina Glajzner, Kamila Olszowiec, Monika Sienkiewicz

“…The presence of the vga gene encoding resistance to streptogramins A was detected in one strain. …”
Get full text

CD63 Promotes Hemocyte-Mediated Phagocytosis in the Clam, Paphia undulata by Mingjia Yu, Shanjun Yang, Hongxia Sun, Qiang Xia

“…The complete cDNA of Pu-CD63 is 1,738 bp in length with an open reading frame (ORF) of 849 bp, encoding a 282 amino acid protein with four putative hydrophobic transmembrane helixes. …”
Get full text

Robust Automated Harmonization of Heterogeneous Data Through Ensemble Machine Learning: Algorithm Development and Validation Study by Doris Yang, Doudou Zhou, Steven Cai, Ziming Gan, Michael Pencina, Paul Avillach, Tianxi Cai, Chuan Hong

“…However, given differences in variable encoding, accurate variable harmonization is difficult. …”
Get full text

HDN-DDI: a novel framework for predicting drug-drug interactions using hierarchical molecular graphs and enhanced dual-view representation learning by Jinchen Sun, Haoran Zheng

“…HDN-DDI integrates an explainable substructure extraction module to decompose drug molecules and represents them using innovative hierarchical molecular graphs, which effectively incorporates information from real chemical substructures and improves molecules encoding efficiency. Furthermore, the enhanced dual-view learning method inspired by the underlying mechanisms of DDIs enables HDN-DDI to comprehensively capture both hierarchical structure and interaction information. …”
Get full text

Emergence of SARS-CoV-2 subgenomic RNAs that enhance viral fitness and immune evasion. by Harriet V Mears, George R Young, Theo Sanderson, Ruth Harvey, Jamie Barrett-Rodger, Rebecca Penn, Vanessa Cowton, Wilhelm Furnon, Giuditta De Lorenzo, Margaret Crawford, Daniel M Snell, Ashley S Fowler, Anob M Chakrabarti, Saira Hussain, Ciarán Gilbride, Edward Emmott, Katja Finsterbusch, Jakub Luptak, Thomas P Peacock, Jérôme Nicod, Arvind H Patel, Massimo Palmarini, Emma Wall, Bryan Williams, Sonia Gandhi, Charles Swanton, David L V Bauer

“…Here, we demonstrate that this TRS leads to the expression of a novel subgenomic mRNA encoding a truncated C-terminal portion of Nucleocapsid, which is an antagonist of type I interferon production and contributes to viral fitness during infection. …”
Get full text

Molecular, Biochemical, and Clinical Characterization of Thirteen Patients with Glycogen Storage Disease 1a in Malaysia by Siti Aishah Abdul Wahab, Yusnita Yakob, Mohd Khairul Nizam Mohd Khalid, Noraishah Ali, Huey Yin Leong, Lock Hock Ngu

“…GSD1a is caused by a mutation in the G6PC gene encoding glucose-6-phosphatase (G6Pase); an enzyme that catalyses the hydrolysis of glucose-6-phosphate (G6P) to phosphate and glucose. …”
Get full text

Optimization of Conditions for Production of Soluble <i>E. coli</i> Poly(A)-Polymerase for Biotechnological Applications by Igor P. Oscorbin, Maria S. Kunova, Maxim L. Filipenko

“…Interestingly, PAP 1 accumulation correlated with an increase in the plasmid copy number encoding the enzyme, indicating its potential utility as a surrogate marker of PAP 1 activity. …”
Get full text

Right Amygdalar and Temporofrontal Activation During Autobiographic, But Not During Fictitious Memory Retrieval by Hans J. Markowitsch, Alexander Thiel, Mechthild Reinkemeier, Josef Kessler, Adem Koyuncu, Wolf-Dieter Heiss

“…Portions of the neural activation found during retrieval might, however, reflect re-encoding processes as well.…”
Get full text

Correlation between P-glycoprotein and CD34 Expressions in Leukemic Cells from De novo Acute Myeloid Leukemia by Yulia Nadar Indrasari, Yetti Hernaningsih, Aryati Aryati, Siprianus Ugroseno Yudho Bintoro, Atika Atika, Rosline Hassan

“…P-glycoprotein (Pgp) is the membrane transporter encoded by the multidrug resistance (MDR1) gene, which is responsible for the efflux of several chemotherapeutic drugs for the treatment of AML. …”
Get full text