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2081
GenVFNet: Generating Visual Field From Optical Coherence Tomography Angiography by Conditional Generative Adversarial Networks
Published 2024-01-01“…The generator consisted of encoder and decoder blocks and the discriminator was the classification learner. …”
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2082
Clinical Usefulness of Bioavailable Vitamin D and Impact of GC Genotyping on the Determination of Bioavailable Vitamin D in a Korean Population
Published 2019-01-01“…The role of genotyping of GC, a gene encoding VDBP, in the determination of bioavailable 25(OH)D concentration in a Korean population was also evaluated. …”
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2083
Altered functional brain connectivity in Dyt1 knock-in mouse models
Published 2025-02-01“…It is the most common hereditary form of primary dystonia, caused by a trinucleotide GAG deletion in the DYT1 gene, which encodes the TorsinA protein. Recent studies conceptualized dystonia as a functional network disorder involving basal ganglia, thalamus, cortex and cerebellum. …”
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2084
Designing and modeling an intelligent system for managing the distribution and scheduling of farmed fish feed using the Arduino Uno microcontroller
Published 2023-09-01“…Materials and methods: The main components of the fish feed distribution and scheduling system consist of three essential elements: the Arduino Uno board, serving as a programmable platform; a servo motor with a single output shaft capable of positioning itself at a specific angle by receiving encoded signals; and a feeder, functioning as a storage and dispensing container for fish feed in the aquaculture system. …”
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2085
Impact of Low Inclusion Rate of Olive Cake in Dairy Cow Rations on Uterine Health and Fertility Indices During Early Lactation
Published 2025-01-01“…Uterine epithelial cells were assessed for polymorphonuclear neutrophil (PMN) counts, and the expression of nine genes encoding inflammatory cytokines and immune system activation was analyzed in uterine biopsy tissue. …”
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2086
Targets of influenza human T-cell response are mostly conserved in H5N1
Published 2025-02-01“…Based on these observations, and the overall similarity of the neuraminidase (NA) N1 subtype encoded in both HPAI and seasonal H1N1 influenza virus as well as cross-reactive group 1 HA stalk-reactive antibodies, we expect that a degree of pre-existing immunity is present in the general human population that could blunt the severity of human H5N1 infections.IMPORTANCEInfluenza A viruses (IAVs) cause pandemics that can result in millions of deaths. …”
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2087
Molecular identification of Leptospira spp. in urine samples from female water buffaloes. Preliminary results
Published 2023-11-01“…Additionally, Internal 1 and Internal 2 were derived from the sequence of the gene encoding the LipL32 protein and specific to identify pathogenic leptospira, described by Haake et al. (2000). …”
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2088
Recombinant α-Klotho Protein Alleviated Acute Cardiorenal Injury in a Mouse Model of Lipopolysaccharide-Induced Septic Cardiorenal Syndrome Type 5
Published 2019-01-01“…Klotho is an aging-suppressor gene mainly expressed in the renal tubules. The klotho gene encodes the α-klotho protein, which has many functions. …”
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2089
Molecular Patterns of MEFV Gene Mutations in Egyptian Patients with Familial Mediterranean Fever: A Retrospective Cohort Study
Published 2019-01-01“…It is characterized by recurrent episodes of fever, polyserositis, and rash. MEFV gene, encoding pyrin protein, is located on the short arm of chromosome 16. …”
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2090
Major facility superfamily sugar transporter protein SsMFSST1 regulates Sporisorium scitamineum mating, pathogenicity, and sugar transport/absorption
Published 2025-02-01“…This study was based on the transcriptome sequencing data of two isolates with different pathogenicities (Ss16 and Ss47) of the S. scitamineum and screened out a gene encoding the Major Facility Superfamily (MFS) sugar transporter protein and named it SsMFSST1. …”
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2091
Chickens productivity selection affects immune system genes
Published 2020-12-01“…Artificial breeding of chickens leads to degradation of the variability of genes encoding elements of the immune system, which can cause a decrease in resistance to various diseases. …”
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2092
A Case Study Identified a New Mutation in the TTN Gene for Inherited Hypertrophic Cardiomyopathy
Published 2025-01-01“…Although mutations in genes encoding sarcomere proteins have been reported to explain the genetic etiology of 40%-60% of HCM patients, the etiology of approximately 1/3 of HCM patients remains unknown. …”
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2093
Transcription factors MhyFIL1 and MhyFIL3 <i>(Monotropa hypopitys)</i> determine the asymmetric development of above-ground lateral organs in plants
Published 2019-07-01“…In this study, the structural and phylogenetic analysis of the pinesap vegetative genes MhyFIL1 and MhyFIL3 is performed, the main conserved domains and motifs of the encoded proteins are characterized, and it is confirmed that the genes belong to the vegetative clade YABBY3/FIL. …”
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2094
Search for and functional annotation of multi-domain PLA2 family proteins in flatworms
Published 2025-01-01“…The paper provides a search for and a comparative analysis of PLA2 sequences encoded in the genomes of flatworms. 44 species represented by two free-living and 42 parasitic organisms were studied. …”
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2095
Screening of West Siberian patients with primary congenital glaucoma for CYP1B1 gene mutations
Published 2020-12-01“…Mutations in the CYP1B1 gene, which encodes cytochrome P450 1B1, are the most common cause of autosomal recessive primary congenital glaucoma. …”
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2096
Acinetobacter baumannii infection in critically ill patients with COVID-19 from Tehran, Iran: the prevalence, antimicrobial resistance patterns and molecular characteristics of iso...
Published 2025-01-01“…The most prevalence carbapenem resistance encoding genes were bla-OXA-23 65.1% (29/43) and blaNDM 41.8% (18/43). …”
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2097
EPIGENETICS TODAY AND TOMORROW
Published 2015-01-01“…Epigenetics is a science of inheritable organism properties that are not associated with changes in the DNA nucleotide sequence but can be indirectly encoded in the genome. The most known epigenetic mechanisms (signals) are enzymatic DNA methylation, the histone code (various enzymatic histone modifications including acetylation, methylation, phosphorylation, ubiquitination and others), and gene silencing mediated by small RNAs (miRNA, siRNA). …”
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2098
mRNA-LNP vaccines combined with tPA signal sequence elicit strong protective immunity against Klebsiella pneumoniae
Published 2025-01-01“…In the present study, we aim to construct a new mRNA vaccine encoding YidR or combining with a tissue plasminogen activator signal sequence for preventing K. pneumoniae infection. …”
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2099
A novel compound heterozygous mutation in the DYNC2H1 gene in a Chinese family with Jeune syndrome
Published 2025-01-01“…Abstract Background The dynein cytoplasmic two heavy chain 1 (DYNC2H1) gene encodes a cytoplasmic dynein subunit. Cytoplasmic dyneins transport cargo towards the minus end of microtubules and are thus termed the “retrograde” cellular motor. …”
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2100
DNGR-1 limits Flt3L-mediated antitumor immunity by restraining tumor-infiltrating type I conventional dendritic cells
Published 2021-05-01“…To overexpress Flt3L systemically, we performed gene therapy through the hydrodynamic injection of an Flt3L-encoding plasmid. To characterize the immune response, we performed flow cytometry and RNA-Seq of tumor-infiltrating cDC1s.Results Here, we found that cross-presentation of tumor antigens in the steady state was DNGR-1-independent. …”
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