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2041
Understanding Citizens’ Response to Social Activities on Twitter in US Metropolises During the COVID-19 Recovery Phase Using a Fine-Tuned Large Language Model: Application of AI
Published 2025-02-01“…ResultsIn the evaluation of models, GPT-3.5 Turbo with fine-tuning outperformed GPT-3.5 Turbo without fine-tuning and Robustly Optimized Bidirectional Encoder Representations from Transformers Pretraining Approach (RoBERTa)–large with fine-tuning, demonstrating significant accuracy (0.80), recall (0.79), precision (0.79), and F1-score (0.79). …”
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2042
SCN10A gene polymorphism is associated with pain sensitivity and postoperative analgesic effects in patients undergoing gynecological laparoscopy
Published 2025-01-01“…Abstract Background Postoperative pain intensity is influenced by various factors, including genetic variations. The SCN10A gene encodes the Nav1.8 sodium channel protein, which is crucial for pain signal transmission in peripheral sensory neurons. …”
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2043
Biofilm-Producing Bacteria and Risk Factors (Gender and Duration of Catheterization) Characterized as Catheter-Associated Biofilm Formation
Published 2021-01-01“…The presence of PapC as a virulence gene encoding pili correlates with the biofilm formation. …”
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2044
Calcitonin Gene-Related Peptide (Cgrp), Adrenomedullin (Am), Amylin, And Calcitonin (Ct) Receptors And Overlapping Biological Actions
Published 2001-01-01“…Another CGRP receptor isotype remains to be discovered in the cerebellum with no detectable CRLR encoding mRNA. Overlapping biological actions include inhibition of bone resorption obtained predominantly with CT, but also at high concentrations with CGRP, AM, and amylin. …”
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2045
Genomic characteristics and molecular epidemiology of MRSA from medical centers in Mexico: Results from the Invifar network.
Published 2025-01-01“…Of the SCCmec IVa strains, most harbored the Panton-Valentine leukocidin encoding genes.<h4>Conclusion</h4>In this study, the most frequently detected CC was CC5, followed by CC8, and CC93, and the most frequently detected MRSA ST was ST1011, followed by ST5. …”
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2046
Diversity in Adaptive Evolution of Methicillin-Resistant Staphylococcus aureus Clinical Isolates Under Exposure to Continuous Linezolid Stress in vitro
Published 2025-02-01“…Polymerase chain reaction assays and sequencing techniques were performed to detect well-known molecular determinants related to linezolid resistance, including the expression of optrA and cfr, mutations of 23S rRNA gene and ribosomal protein (L3, L4, L22) encoding genes (rplC, rplD, rplV).Results: After induction with sequentially increasing concentrations of linezolid, all four MRSA strains (L914, L860, L1096, and L2875) evolved into linezolid-resistant strains over various induction times (480, 384, 288, and 240 h) and universally formed small colony variants. …”
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2047
Effect of amisulpride on the expression of serotonin receptors, neurotrophic factor BDNF and its receptors in mice with overexpression of the aggregation-prone [R406W] mutant tau p...
Published 2024-07-01“…In this study, we investigated the effects of amisulpride (5-HT7R inverse agonist) in C57BL/6J mice with experimentally induced expression of the gene encoding the aggregation-prone human Tau[R406W] protein in the prefrontal cortex. …”
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2048
Dynamic changes in the gastrointestinal microbial communities of Gangba sheep and analysis of their functions in plant biomass degradation at high altitude
Published 2025-01-01“…Additionally, the catalogue of microbial genomes and the encoded biomass-degrading enzymes identified here provide insights into the potential microbial functions of the gastrointestinal tract of Gangba sheep at high altitudes. …”
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2049
Molecular genetic detection and differentiation of <i>Xanthomonas oryzae</i> pv. <i>oryzicola</i>, bacterial leaf streak agents of rice
Published 2022-10-01“…The SeqX.o.all sequencing primers were selected for the hrp gene cluster sequence, namely for the nucleotide sequence encoding the Hpa1 protein, the sequencing of which allows for eff icient differentiation of X. oryzae species. …”
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2050
Comprehensive approach to predictive analysis and anomaly detection for road crash fatalities
Published 2025-01-01“…A Random Forest Regression model is trained to estimate the number of deaths arising from traffic crashes after data preprocessing, which includes feature selection and encoding. The accuracy and predictive power of the model are assessed through the utilization of the Mean Squared Error measure. …”
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2051
The Pattern of mRNA Expression Is Changed in Sinoatrial Node from Goto-Kakizaki Type 2 Diabetic Rat Heart
Published 2018-01-01“…The expression of genes encoding more than 70 proteins that are associated with the generation and conduction of electrical activity in the GK sinoatrial node (SAN) have been evaluated to further clarify the molecular basis of the low heart rate. …”
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2052
Clinical relevance of macromolecular complexes involving integrins, potassium and sodium ion channels and the sodium/proton antiporter in human breast cancer
Published 2025-01-01“…Methods We analyzed the expression and impact on outcome of the genes encoding the four proteins forming the NHE1/hERG1/β1/nNaV1.5 complex (SLC9A1, KCNH2, ITGB1 and SCN5A) in public datasets. …”
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2053
A recurrent YOLOv8-based framework for event-based object detection
Published 2025-01-01“…ReYOLOv8 incorporates a low-latency, memory-efficient method for encoding event data called Volume of Ternary Event Images (VTEI) and introduces a novel data augmentation technique based on Random Polarity Suppression (RPS) optimized for event-based sensors and tailored to leverage the unique attributes of event data. …”
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2054
Polymorphisms and dental age in non-syndromic cleft lip and palate: a cross-sectional study
Published 2025-01-01“…The purpose of this cross-sectional study was to compare the dental age (DA) between children with and without CL ± P, and whether single nucleotide polymorphisms (SNPs) in genes encoding growth factors are associated with DA variations. …”
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2055
RETRACTED: Melanin Produced by Bordetella parapertussis Confers a Survival Advantage to the Bacterium during Host Infection
Published 2021-10-01“…Here, by screening a transposon library, we demonstrate that the gene encoding 4-hydroxyphenylpyruvate dioxygenase (HppD) is responsible for production of this pigment. …”
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2056
Maternal health risk factors dataset: Clinical parameters and insights from rural BangladeshMendeley Data
Published 2025-04-01“…The study's preprocessing methods, which included data cleaning, normalization, and encoding, ensured high-quality data for statistical analysis. …”
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2057
Candidate SNP markers of social dominance, which may affect the affinity of the TATAbinding protein for human gene promoters
Published 2017-02-01“…The following heuristic hypothesis has been proposed: if an excess of a protein in several animal organs was experimentally identified as physiological marker of increased aggressiveness and if a polymorphism (SNP) can cause superexpression of the human gene homologous of the animal gene encoding this protein, then this polymorphism can be a candidate SNP marker of social dominance, whereas a deficient expression corresponds to subordinate and vice versa. …”
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2058
Prevalence of Hyper virulence and Multidrug resistance Klebsiella pneumoniae isolates from UTI patients
Published 2025-01-01“…Polymerase chain reaction was used to detect the adhesion gene fimH, results showed that (75%) of k. pneumoniae isolates had fimH, rmpA gene responsible for capsule formation and it was found in (66%) of K. pneumoniae, according to bla- TEM gene encoding ESBL, (71.2%) K. pneumoniae isolates had bla-TEM gene. …”
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2059
Marigold: a machine learning-based web app for zebrafish pose tracking
Published 2025-01-01“…First, we examined novel aspects of the touch-evoked escape response in techno trousers (tnt) mutant embryos, which contain a previously described loss-of-function mutation in the gene encoding Eaat2b, a glial glutamate transporter. We identified differences and interactions between touch location (head vs. tail) and genotype. …”
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2060
SHP2 promotes the epithelial-mesenchymal transition in triple negative breast cancer cells by regulating β-catenin
Published 2025-01-01“…Methods In this study, we conducted bioinformatics analysis of the Gene Expression Omnibus (GEO) and The Cancer Genome Atlas (TCGA) databases to examine PTPN11 (encoding SHP2) expression levels and perform survival analysis in TNBC. …”
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