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    Crystal structure of N′,N′′′-((1E,1′E)-(propane-2,2-diylbis(1H-pyrrole-5,2diyl))bis(methaneylylidene))di(nicotinohydrazide) pentahydrate, C25H24N8O2·5H2O by Zhou Yi, Zhang Min, Xiong Ying

    Published 2021-09-01
    “…C25H34N8O7, triclinic, P1‾ $P‾{1}$ (no. 2), a = 7.507(2) Å, b = 8.0276(18) Å, c = 23.653(6) Å, α = 93.062(8)°, β = 97.015(9)°, γ = 99.478(8)°, V = 1391.4(6) Å3, Z = 2, R gt(F) = 0.0473, wR ref(F 2) = 0.1477, T = 273 K.…”
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    A Benzochalcone Derivative, (E)-1-(2-hydroxy-6-methoxyphenyl)-3-(naphthalen-2-yl)prop-2-en-1-one (DK-512), Inhibits Tumor Invasion through Inhibition of the TNFα-Induced NF-κB/MMP-9 Axis in MDA-MB-231 Breast Cancer Cells by Soon Young Shin, Chang Gun Kim, Seunghyun Ahn, You Jung Jung, Dongsoo Koh, Young Han Lee, Yoongho Lim

    Published 2016-01-01
    “…In this study, we synthesized a novel benzochalcone derivative, (E)-1-(2-hydroxy-6-methoxyphenyl)-3-(naphthalen-2-yl) prop-2-en-1-one (DK-512), and characterized its effects on tumor invasion and its mechanism of action. …”
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    In vitro study of size-dependent inhibition of human cytochrome P450 (P450) P450-1A2, P450-2A6, P450-2B6, P450-2C8, P450-2E1, P450-2J2, and P450-3A5 by zinc oxide nanoparticles (ZnONPs) by Lamia Chowdhury, Yuh Fen Pung, Swee Yong Pung, Chin Eng Ong, Cin Kong, Yan Pan

    Published 2025-02-01
    “…ZnOBP competitively inhibited the enzymatic activity of P450-2E1 with Ki value of 28.3 $\mu$g/mL. The inhibition potency observed for P450-2B6, P450-2J2, and P450-2E1 depended on the size of the ZnO particle. …”
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