Assessment of food toxicology by Alexander Gosslau

“…A decrease of rodent animal testing with its limitations of high costs, low throughput readouts, inconsistent responses, ethical issues and concerns of extrapolability to humans have led to an increased use of these but also alternative lower hierarchy surrogate animal models (e.g. Drosophila melanogaster; Caenorhabditis elegans or Danio rerio) and efforts to integrate organotypic systems and stem cell-based assays. …”
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Harnessing Insect Chemosensory and Mechanosensory Receptors Involved in Feeding for Precision Pest Management by Tingwei Mi, Chengwang Sheng, Cassidy Kylene Lee, Peter Nguyen, Yali V. Zhang

“…This review highlights recent advancements in research on feeding-related sensory receptors, covering a wide range of insect species, from the model organism <i>Drosophila melanogaster</i> to agricultural and human pests. …”
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qDATA - an R application implementing a practical framework for analyzing quantitative real-time PCR data by Adrian Ionascu, Alexandru Al. Ecovoiu, Mariana Carmen Chifiriuc, Attila Cristian Ratiu

“…The efficiency of our computing approach was tested using input Ct values corresponding to immune related gene expression evaluated in experimental infection of Drosophila melanogaster and Apis mellifera workers. The presented results reveal that our working strategy is reliable and highlight the efficacy and performance of qDATA application.…”
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Functional divergence caused by ancient positive selection of a Drosophila hybrid incompatibility locus. by Daniel A Barbash, Philip Awadalla, Aaron M Tarone

“…Experimentally tractable models are required to identify and test candidate hybrid incompatibility genes. Several Drosophila melanogaster genes involved in hybrid incompatibility have been identified but none has yet been shown to have functionally diverged in accordance with the Dobzhansky-Muller model. …”
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PIWI proteins and piRNAs: key regulators of stem cell biology by Fernando Claro-Linares, Patricia Rojas-Ríos

“…Initially identified in Drosophila melanogaster, the piRNA pathway regulate germline stem cell self-renewal and differentiation via cell-autonomous and non-cell-autonomous mechanisms. …”
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Enhancing Biocide Safety of Milk Using Biosensors Based on Cholinesterase Inhibition by Lynn Mouawad, Georges Istamboulie, Gaëlle Catanante, Thierry Noguer

“…Acetylcholinesterase from <i>Drosophila melanogaster</i> (DM AChE) and butyrylcholinesterase from horse serum (BChE) were immobilized by entrapment in a photocrosslinkable polymer on the surface of carbon screen-printed electrodes. …”
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Whole organism and tissue-specific analysis of pexophagy in Drosophila by Francesco G. Barone, Marco Marcello, Sylvie Urbé, Natalia Sanchez-Soriano, Michael J. Clague

“…We have generated transgenic Drosophila melanogaster models expressing fluorescent reporters for the selective autophagy of peroxisomes, a process known as pexophagy. …”
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Spherical harmonics texture extraction for versatile analysis of biological objects. by Oane Gros, Josiah B Passmore, Noa O Borst, Dominik Kutra, Wilco Nijenhuis, Timothy Fuqua, Lukas C Kapitein, Justin M Crocker, Anna Kreshuk, Simone Köhler

“…The Spherical Texture extraction characterizes biologically defined gene expression patterns in Drosophila melanogaster embryos, giving a quantitative read-out for pattern formation. …”
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Characterization of Nora Virus Structural Proteins via Western Blot Analysis by Brad L. Ericson, Darby J. Carlson, Kimberly A. Carlson

“…To determine the polypeptide composition of Nora virus virions, polypeptides from purified virus were compared to polypeptides detected in Nora virus infected Drosophila melanogaster. Nora virus was purified from infected flies and used to challenge mice for the production of antisera. …”
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Evaluation of Type III Adhesive Mortar (ACIII) and Gypsum as Precipitating Agents of Copper and Lead by Jefferson Luiz Alves Marinho, Henrique Douglas Melo Coutinho, Raimundo Nonato Pereira Teixeira, Jorge Marcell Coelho Menezes, Francisco José de Paula Filho, Francisco Assis Bezerra da Cunha

“…Therefore, the present study aimed to assess the potential of gypsum and adhesive mortar type III (ACIII) as precipitating agents for lead (Pb) and copper (Cu) ions, as well as to evaluate the toxicity of precipitation products on Drosophila melanogaster. Experiments using ACIII mortar waste as a precipitating agent for Cu ions were obtained using a glass filter composed of 04 chambers and 04 antechambers, while the potential of gypsum as a Pb ion precipitant was evaluated by adding gypsum powder to a beaker containing a Pb ions solution. …”
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DICER1: The Argonaute Endonuclease Family Member and Its Role in Pediatric and Youth Pathology by Consolato M. Sergi, Fabrizio Minervini

“…In 2001, two enzyme-encoding genes were recognized in the fruit fly <i>Drosophila melanogaster</i>. The genetic material, labeled <i>Dicer-1</i> and <i>Dicer-2</i>, encodes ribonuclease-type enzymes with slightly diverse target substrates. …”
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Mechanisms of transcriptional regulation of ecdysone response by M. Yu. Mazina, N. E. Vorobyeva

“…Initially, the activation of individual genes under the influence of ecdysone was studied on the model of polythene chromosomes from salivary glands of Drosophila melanogaster. These works helped to investigate the many aspects of the Drosophila development. …”
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The role of SAGA in the transcription and export of mRNA by E. N. Nabirochkina, M. M. Kurshakova, S. G. Georgieva, D. V. Kopytova

“…We studied the DUBm of SAGA in Drosophila melanogaster and identified Drosophila homologs of yeast DUBm components. …”
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Drosophila Mutant Model of Parkinson’s Disease Revealed an Unexpected Olfactory Performance: Morphofunctional Evidences by Francescaelena De Rose, Valentina Corda, Paolo Solari, Patrizia Sacchetti, Antonio Belcari, Simone Poddighe, Sanjay Kasture, Paolo Solla, Francesco Marrosu, Anna Liscia

“…We sought to use the fruit fly Drosophila melanogaster as a model organism to explore olfactory function in LRRK loss-of-function mutants, which was previously demonstrated to be a useful model for PD. …”
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Toward the Development of the Trojan Female Technique in Pest Insects: Male‐Specific Influence of Mitochondrial Haplotype on Reproductive Output in the Seed Beetle Acanthoscelides... by Lea Vlajnić, Uroš Savković, Jelena Jović, Sanja Budečević, Biljana Stojković, Mirko Đorđević

“…Although TFT has been theoretically substantiated, empirical work to date has focused only on Drosophila melanogaster populations, while the existence of male‐biased mutations and the TFT approach in economically important pest species remain unexplored. …”
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Human APP Gene Expression Alters Active Zone Distribution and Spontaneous Neurotransmitter Release at the Drosophila Larval Neuromuscular Junction by Ekaterina A. Saburova, Alexander N. Vasiliev, Violetta V. Kravtsova, Elena V. Ryabova, Andrey L. Zefirov, Olga I. Bolshakova, Svetlana V. Sarantseva, Igor I. Krivoi

“…Experiments were performed on larval neuromuscular junctions of transgenic Drosophila melanogaster lines with different levels of human amyloid precursor protein (APP) production. …”
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LIM-kinase 1 effects on memory abilities and male courtship song in Drosophila depend on the neuronal type by A. V. Zhuravlev, E. S. Zalomaeva, E. S. Egozova, A. D. Emelin, V. V. Sokurova, E. A. Nikitina, E. V. Savvateeva-Popova

“…The signal pathway of actin remodeling, including LIM-kinase 1 (LIMK1) and its substrate cofilin, regulates multiple processes in neurons of vertebrates and invertebrates. Drosophila melanogaster is widely used as a model object for studying mechanisms of memory formation, storage, retrieval and forgetting. …”
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Synaptic enrichment and dynamic regulation of the two opposing dopamine receptors within the same neurons by Shun Hiramatsu, Kokoro Saito, Shu Kondo, Hidetaka Katow, Nobuhiro Yamagata, Chun-Fang Wu, Hiromu Tanimoto

“…In the fruit fly Drosophila melanogaster, Dop1R1 and Dop2R encode the D1- and D2-like receptors, respectively, and are reported to oppositely regulate intracellular cAMP levels. …”
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Diversity and functions of fungal VOCs with special reference to the multiple bioactivities of the mushroom alcohol by Guohua Yin, Geromy G. Moore, Joan Wennstrom Bennett

“…It is also produced by certain plants and functions as a semiochemical for numerous arthropods. The use of Drosophila melanogaster (fruit flies) as a model for testing the toxicity of fungal VOCs showed that some VOCs delayed metamorphosis and/or caused fly death at certain concentrations. …”
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Potential of emodepside for vector-borne disease control by Pattarapon Khemrattrakool, Thitipong Hongsuwong, Theerawit Phanphoowong, Patchara Sriwichai, Kittiyod Poovorawan, Joel Tarning, Kevin C. Kobylinski

“…Emodepside also has activity against Drosophila melanogaster SLO-1 channels. Orthologous SLO-1 genes are present in Anopheles gambiae and Aedes aegypti, suggesting that emodepside may have activity against mosquitoes. …”
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